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GCIP Anticuerpos

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un sistema único para la rápida identificación de GCIP Anticuerpos. Desplace el puntero sobre los nombres de los productos de la tabla para ver los datos representativos de cada producto.

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NOMBRE DEL PRODUCTO NÚMERO DEL CATÁLOGO:ISOTIPOEPíTOPOAPLICACIONESESPECIESMENCIONESCLASIFICACIÓN
GCIP (D-16)sc-160359cabra IgGInternal (h)WB, IF, ELISAm, r, h
GCIP (E-19)sc-160360cabra IgGInternal (h)WB, IP, IF, ELISAm, h, c, b
GCIP (S-14)sc-160362cabra IgGInternal (m)WB, IP, IF, ELISAm, r
GCIP (T-14)sc-160363cabra IgGInternal (h)WB, IF, ELISAhumano

GCIP silenciadores génicos siARN, Plásmidos de shARN y Partículas Lentivirales shRNA incluyendo:

siRNAsPlásmidos shRNAshRNA partículas antiviralesMENCIONESCLASIFICACIÓN
GCIP siRNA (h): sc-90019GCIP shRNA Plasmid (h):
sc-90019-SH
GCIP shRNA (h)
Partículas Lentiviral  :sc-90019-V
GCIP siRNA (m): sc-145361GCIP shRNA Plasmid (m):
sc-145361-SH
GCIP shRNA (m)
Partículas Lentiviral  :sc-145361-V

GCIP (Grap2 (Gads) and cyclin D-interacting protein), also known as cyclin D-type binding-protein 1 (CCNDBP1), human homolog of maid (HHM) or DIP1, is a 360 amino acid cytoplasmic and nuclear protein belonging to the CCNDBP1 family. GCIP is interacts with cyclin D and Gads, a leukocyte-specific adaptor protein known to influence immune cell signaling. Suggested to regulate cell cycle progression, GCIP acts as a negative regulator of liver-specific gene expression and prevents Rb phosphorylation by inhibiting the Cdk4/cyclin D complex. GCIP expression is down-regulated in a number of tumors including those found in rectum, breast, prostate and colon, but up-regulated in hepatic cancers. GCIP is ubiquitously expressed and exists as at least four alternatively spliced isoforms whose expression likely increases during differentiation and can be induced by sodium butyrate.