NYD-SP15 Antibody (3C8): sc-81998

NYD-SP15 Antibody (3C8) is a mouse monoclonal IgG1 kappa light chain antibody that detects NYD-SP15 in mouse, rat, and human samples by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). NYD-SP15 (3C8) antibody is available as the non-conjugated format. NYD-SP15, also known as CDADC1 (cytidine and dCMP deaminase domain containing 1), plays a crucial role in testis development and is predominantly expressed in testis, liver, spleen, kidney, thymus, and placenta. With a length of 514 amino acids, NYD-SP15 belongs to the cytidine and deoxycytidylate deaminase family and is developmentally regulated, showing higher expression levels in adult testis compared to fetal testis. This regulation suggests NYD-SP15 involvement in spermatogenesis and testicular development, making NYD-SP15 a potential factor in male infertility. Alternative splicing of NYD-SP15 results in four distinct transcript variants, which may contribute to functional diversity and regulatory mechanisms in reproductive biology.

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NYD-SP15 Antibody (3C8) References:

1. [Search for transcribed segments in the region of q14.3 of human chromosome 13 in silico].  |  Tiazhelova, TV., et al. 2004. Genetika. 40: 422-6. PMID: 15125259
2. Alteration of gene expression in response to bone morphogenetic protein-2 in androgen-dependent human prostate cancer LNCaP cells.  |  Kumagai, T., et al. 2006. Int J Mol Med. 17: 285-91. PMID: 16391828
3. NYD-SP15: a novel gene potentially involved in regulating testicular development and spermatogenesis.  |  Liu, Q., et al. 2006. Biochem Genet. 44: 409-23. PMID: 16955368
4. Molecular features linked to the growth-inhibitory effects of gemcitabine on human pancreatic cancer cells.  |  Toshimitsu, H., et al. 2006. Oncol Rep. 16: 1285-91. PMID: 17089051

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-NYD-SP15 Antibody (3C8) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-NYD-SP15 Antibody (3C8) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

NYD-SP15 Antibody (3C8) Specifications

Alternate Product Name: NYD-SP15

Product Clone Name: 3C8

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 423-515

Epitope Target: NYD-SP15

Epitope Species: human

Product Reactivity/Detection: NYD-SP15

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for NYD-SP15 Antibody (3C8): N/A