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p-Stat3 Anticuerpo(B-7): sc-8059

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(Basado en el análisis de datos)

  • p-Stat3 Antibody (B-7) is a mouse monoclonal IgG2b provided at 200 µg/ml
  • recommended for detection of Stat3 of mouse, rat and human origin phosphorylated at Tyr 705 by WB, IP, IF. IHC(P), FCM and ELISA
  • blocking peptide, sc-8059 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-8059 X, 200 µg/0.1 ml
  • phycoerythrin (sc-8059 PE), PerCP (sc-8059 PerCP) and PerCP-Cy5.5 (sc-8059 PCPC5) conjugates for intracellular FCM, 100 tests
  • agarose conjugate for IP studies, sc-8059 AC, 500 µg/0.25 ml agarose
  • for phosphorylation positive (sc-2222) and non-activated control (sc-2200) cell extracts
  • See 100 citations for p-Stat3 Anticuerpo (B-7)
 

Ver tambiénStat AntibodiesincluyebdoStat, Stat1, Stat5A/B, Stat2, Stat3, Stat4, Stat5yStat6.

También verStat3 Inhibitors for functional analysis of cellular responses to Stat3.


Información sobre pedidosMenciones del ProductoInformación del gen
Productos Complementarios Recomendados:
(Haga click en el botón de la aplicación que desee)
WB   IP   IF   IHC(P)   FCM   Gel Shift   ChIP   siRNA  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
p-Stat3 Antibody (B-7) sc-8059 200 µg/ml $279
p-Stat3 Antibody (B-7) AC sc-8059 AC 500 µg/ml, 25% ag $366
p-Stat3 (B-7) P sc-8059 P
(peptide)
 100 µg/0.5 ml $61
p-Stat3 Antibody (B-7) PCPC5 sc-8059 PCPC5 100 tests in 2 ml $310
p-Stat3 Antibody (B-7) PE sc-8059 PE 100 tests in 2 ml $303
p-Stat3 Antibody (B-7) PerCP sc-8059 PerCP 100 tests in 2 ml $310
p-Stat3 Antibody (B-7) X sc-8059 X 200 µg/0.1 ml $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 Silenciadores de Genes siRNA (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
Stat3 siRNA (h) sc-29493 10 µM $258
Stat3 siRNA (m) sc-29494 10 µM $258
Stat3 (h)-PR sc-29493-PR 10 µM, 20 µl $23
Stat3 (m)-PR sc-29494-PR 10 µM, 20 µl $23
 Plásmidos shRNA (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
Stat3 shRNA Plasmid (h) sc-29493-SH 20 µg $520
Stat3 shRNA Plasmid (m) sc-29494-SH 20 µg $520
 shRNA partículas antivirales (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
Stat3 shRNA (h) Lentiviral Particles sc-29493-V 200 µl $625
Stat3 shRNA (m) Lentiviral Particles sc-29494-V 200 µl $625
 Lisado de células para control positivo de WB (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
HeLa + IFN-γ Cell Lysate sc-2222 500 µg/200 µl $104
SK-MEL-28 + IFN-γ Cell Lysate sc-2291 500 µg/200 µl $104
Stat3 (m): 293T Lysate sc-126053 100 µg/200 µl $205
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
Stat3 (m2): 293T Lysate sc-126054 100 µg/200 µl $205
SK-MEL-28 + IFN-α Cell Lysate sc-2290 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
A-431 + EGF Whole Cell Lysate sc-2202 500 µg/200 µl $104
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano STAT3 6774 17q21.2 NM_003150, NM_139276, NM_213662 P40763
 102582
Ratón Stat3 20848 11 D P42227
 No Disponible
 

Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-a and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3∫ appears to be activated by both while Stat3å is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.

p-Stat3 Antibody (B-7) Menciones del Producto
Vea como otros han usado anticuerpos %catalog_number% y/o anticuerpos conjugados p-Stat3 (B-7).


100 menciones totales
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p-Stat3 Antibody (B-7) Data
Haga click en la imágen para agrandarla
sc-8059
Western blot analysis of Stat3 activation in untreated (A,C) and γ-interferon-induced (B,D) HeLa cells. Antibodies tested include a phospho-specific Stat3 monoclonal, p-Stat3 (B-7): sc-8059 (A,B) and a control antibody, Stat3 (F-2): sc-8019 (C,D).
sc-8059
p-Stat3 (B-7) PE: sc-8059 PE. Intracellular FCM analysis of fixed and permeabilized control (green line histogram) and IFN-γ-induced (solid orange histogram) U-937 cells. Dotted pink histogram represents the isotype control, normal mouse IgG2b: sc-2868.
sc-8059
p-Stat3 (B-7): sc-8059. Western blot analysis of Stat3 phosphorylation in non-transfected: sc-117752 (A) and mouse Stat3 transfected: sc-126053 (B) 293T whole cell lysates.
sc-8059
p-Stat3 (B-7): sc-8059. Western blot analysis of Stat3 phosphorylation in non-transfected: sc-117752 (A) and mouse Stat3 transfected: sc-126054 (B) 293T whole cell lysates.
sc-8059
p-Stat3 (B-7): sc-8059. Western blot analysis of Stat3 phosphorylation in untreated (A), IFNγ-treated (B) and IFNγ and lambda protein phosphatase treated (C) SK-MEL-28 whole cell lysates.
sc-8059
Western blot analysis of Stat3 phosphorylation in untreated (A,D), mouse LIF (sc-4989) treated (B,E) and LIF and lambda protein phosphatase (sc-200312A) treated (C,F) 3T3-L1 whole cell lysates. Antibodies tested include p-Stat3 (B-7): sc-8059 (A,B,C) and Stat3 (F-2): sc-8019 (D,E,F).
sc-8059
Western blot analysis of Stat3 phosphorylation in untreated (A,D), human LIF (sc-4988) treated (B,E) and LIF and lambda protein phosphatase (sc-200312A) treated (C,F) TT whole cell lysates. Antibodies tested include p-Stat3 (B-7): sc-8059 (A,B,C) and Stat3 (F-2): sc-8019 (D,E,F).
sc-8059
Western blot analysis of Stat3 phosphorylation in untreated (A,C) and IFNα treated (B,D) SK-MEL-28 whole cell lysates. Antibodies tested include p-Stat3 (B-7): sc-8059 (A,B) and Stat3 (F-2): sc-8019 (C,D).
sc-8059
Western blot analysis of Stat3 phosphorylation in untreated (A,D), mouse LIF (sc-4989) treated (B,E) and LIF and lambda protein phosphatase (sc-200312A) treated (C,F) 3T3-L1 whole cell lysates. Antibodies tested include p-Stat3 (B-7): sc-8059 (A,B,C) and Stat3 (F-2): sc-8019 (D,E,F).
sc-8059
Western blot analysis of Stat3 phosphorylation in untreated (A,D), human LIF (sc-4988) treated (B,E) and LIF and lambda protein phosphatase (sc-200312A) treated (C,F) TT whole cell lysates. Antibodies tested include p-Stat3 (B-7): sc-8059 (A,B,C) and Stat3 (F-2): sc-8019 (D,E,F).
sc-8059
p-Stat3 (B-7): sc-8059. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lung tissue showing nuclear staining of subset of pneumocytes.
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