BAT4 Background Information BAT4, also known as ANKRD59, G5 or GPATCH10, is a 356 amino acid protein that contains one G-patch domain and two ANK repeats and is thought to play a role in immunity-related events throughout the body. The BAT4 gene maps within a cluster of BAT genes on human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
