VEGF-C Antibody (F-10): sc-74585

VEGF-C Antibody (F-10) is a mouse monoclonal IgG2a antibody that detects VEGF-C in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). VEGF-C is a crucial member of the vascular endothelial growth factor family, primarily known for its role in lymphangiogenesis, the formation of lymphatic vessels, which is essential for maintaining fluid homeostasis and immune responses. VEGF-C is predominantly expressed in lymphatic endothelial cells and plays a significant role in promoting the growth and permeability of lymphatic vessels, which can be particularly important in the context of cancer metastasis, as VEGF-C facilitates the spread of tumor cells through the lymphatic system. Additionally, VEGF-C interacts with specific receptors, such as Flt-4 and Flk-1, which are vital for mediating biological effects. VEGF-C′s ability to induce lymphatic endothelial cell proliferation and migration underscores VEGF-C′s importance in both normal physiological processes and pathological conditions, making anti-VEGF-C antibody (F-10) an invaluable tool for researchers studying angiogenesis and lymphangiogenesis in various disease models.

The preferred VEGF-C antibody is VEGF-C Antibody (E-6): sc-374628.