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p-ERK Anticuerpo(E-4): sc-7383

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  • p-ERK Antibody (E-4) is a mouse monoclonal IgG2a provided at 200 µg/ml
  • epitope corresponding to a short amino acid sequence containing phosphorylated Tyr 204 of ERK 1 of human origin (identical to corresponding ERK2 sequence)
  • recommended for detection of ERK 1 phosphorylated at Tyr 204 and correspondingly phosphorylated ERK 2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-7383 P
  • agarose conjugate for IP studies, sc-7383 AC, 500 µg/0.25 ml agarose
  • fluorescein (sc-7383 FITC) and rhodamine (sc-7383 TRITC) conjugates for immunofluorescence, 200 µg/ml
  • for phosphorylation positive (sc-2221) and non-activated control (sc-2200) cell extracts
  • phycoerythrin (sc-7383 PE), PerCP (sc-7383 PerCP) and PerCP-Cy5.5 (sc-7383 PCPC5) conjugates for FCM, 100 tests
  • Alexa Fluor® 405 (sc-7383 AF405), Alexa Fluor® 488 (sc-7383 AF488) and Alexa Fluor® 647 (sc-7383 AF647) conjugates for immunofluorescence; 100 µg/2 ml
  • See 766 citations for p-ERK Anticuerpo (E-4)
 

Ver tambiénERK AntibodiesincluyebdoERK, ERK 1, ERK 2, ERK 3, ERK 4yERK 5.

También verERK Inhibitors, ERK ActivatorsoERK Substrates for functional analysis of cellular responses to ERK.


Información sobre pedidosMenciones del ProductoInformación del gen
Productos Complementarios Recomendados:
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WB   IP   IF   IHC(P)  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
p-ERK Antibody (E-4) sc-7383 200 µg/ml $279
p-ERK Antibody (E-4) AC sc-7383 AC 500 µg/ml, 25% ag $366
p-ERK Antibody (E-4) Alexa Fluor® 405 sc-7383 AF405 100 µg/2 ml $314
p-ERK Antibody (E-4) Alexa Fluor® 488 sc-7383 AF488 100 µg/2 ml $314
p-ERK Antibody (E-4) Alexa Fluor® 647 sc-7383 AF647 100 µg/2 ml $314
p-ERK Antibody (E-4) FITC sc-7383 FITC 200 µg/ml $282
p-ERK (E-4) P sc-7383 P
(peptide)
 100 µg/0.5 ml $61
p-ERK Antibody (E-4) PCPC5 sc-7383 PCPC5 100 tests in 2 ml $310
p-ERK Antibody (E-4) PE sc-7383 PE 100 tests in 2 ml $303
p-ERK Antibody (E-4) PerCP sc-7383 PerCP 100 tests in 2 ml $310
p-ERK Antibody (E-4) TRITC sc-7383 TRITC 200 µg/ml $282
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 Lisado de células para control positivo de WB (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
NIH/3T3 + PDGF Cell Lysate sc-3803 500 µg/200 µl $104
Jurkat + PMA Cell Lysate sc-24718 500 µg/200 µl $104
ERK 1 (m): 293T Lysate sc-126806 100 µg/200 µl $205
HeLa + UV Cell Lysate sc-2221 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano MAPK3 5595 16p11.2 NM_001040056, NM_002746 P27361
 601795
Ratón Mapk3 26417 7 F3 Q63844
 No Disponible
 

The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, designated extracellular-signal related kinase 1 (ERK 1) and ERK 2, respectively. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. Phosphorylation at both the Thr and Tyr residues is required for full enzymatic activation. In response to activation, MAP kinases phosphorylate downstream components on serine and threonine. Upstream MAP kinase regulators include MAP kinase kinase (MEK), MEK kinase and Raf-1. The ERK family has three additional members: ERK 3, ERK 5 and ERK 6.

p-ERK Antibody (E-4) Menciones del Producto
Vea como otros han usado anticuerpos %catalog_number% y/o anticuerpos conjugados p-ERK (E-4).


765 menciones totales
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p-ERK Antibody (E-4) Data
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sc-7383
Western blot analysis of ERK activation in untreated (A,C) and UV-irradiated (B,D) HeLa cells. Antibodies tested include a control antibody, ERK 1 (K-23): sc-94 (A,B) and a phospho-ERK-specific antibody, p-ERK (E-4): sc-7383 (C,D).
sc-7383
p-ERK (E-4): sc-7383. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing nuclear localization of activated ERK.
sc-7383
p-ERK (E-4): sc-7383. Western blot analysis of ERK 1 phosphorylation in non-transfected 293T: sc-117752 (A), mouse ERK 1 transfected 293T: sc-126806 (B) and A-431 (C) whole cell lysates.
sc-7383
p-ERK (E-4): sc-7383. Western blot analysis of ERK phosphorylation in untreated (A), PDGF treated (B) and PDGF and lambda protein phosphatase treated (C) NIH-3T3 whole cell lysates.
sc-7383
Western blot analysis of ERK phosphorylation in untreated (A, C), and lambda protein phosphatase treated (B, D) NIH/3T3 whole cell lysates. Antibodies tested include p-ERK (E-4): sc-7383 (A, B) and ERK 2 (K-23): sc-153 (C, D).
sc-7383
p-ERK (E-4): sc-7383. Western blot analysis of ERK phosphorylation in untreated (A) and Raf Kinase Inhibitor V (sc-222241) treated (B) SK-MEL-28 whole cell lysates. Note inhibition of ERK phosphorylated in lane B.
sc-7383
Western blot analysis of ERK phosphorylation in untreated (A,C) and Sorafenib (sc-220125) treated (B,D) SK-MEL-28 whole cell lysates. Antibodies tested include p-ERK (E-4): sc-7383 (A,B) and ERK 2 (K-23): sc-153 (C,D). Note inhibition of ERK phosphorylation by Sorafenib in lane B.
sc-7383
Western blot analysis of ERK phosphorylation in untreated (A,C) and Sorafenib (sc-220125) treated (B,D) SW480 whole cell lysates. Antibodies tested include p-ERK (E-4): sc-7383 (A,B) and ERK 2 (K-23): sc-153 (C,D). Note inhibition of ERK phosphorylation by Sorafenib in lane B.
sc-7383
Western blot analysis of ERK phosphorylation in untreated (A) and L-779,450 (sc-204046) treated (B) SK-MEL-28 whole cell lysates. Antibody tested is p-ERK (E-4): sc-7383 (A,B). Note inhibition of ERK phosphorylation by L-779,450 in lane B.
sc-7383
Western blot analysis of ERK phosphorylation in untreated (A) and L-779,450 (sc-204046) treated (B) SW480 whole cell lysates. Antibody tested is p-ERK (E-4): sc-7383 (A,B). Note inhibition of ERK phosphorylation by L-779,450 in lane B.
sc-7383
Western blot analysis of ERK phosphorylation in untreated (A) and PD 0325901 (sc-205427) treated (B) SK-MEL-28 whole cell lysates. Antibody tested is p-ERK (E-4): sc-7383 (A,B). Note inhibition of ERK phosphorylation by PD 0325901 in lane B.
sc-7383
Western blot analysis of ERK phosphorylation in untreated (A) and PD 0325901 (sc-205427) treated (B) SW480 whole cell lysates. Antibody tested is p-ERK (E-4): sc-7383 (A,B). Note inhibition of ERK phosphorylation by PD 0325901 in lane B.
sc-7383
p-ERK (E-4): sc-7383. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing nuclear localization of activated ERK.
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