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HSV-2 ICP10 Anticuerpo(15206): sc-73440

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(Basado en el análisis de datos)
  • HSV-2 ICP10 Antibody (15206) is a mouse monoclonal IgG1 provided at 100 µg/ml
  • raised against HSV-1/2 infected cells
  • recommended for detection of ICP10 of HSV-2 origin by IF; non cross-reactive with HSV-1
 

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HSV-2 ICP10 Antibody (15206) sc-73440 100 µg/ml $279

The herpes simplex virus (HSV) (also known as cold sore, night fever or fever blister) is a virus that causes a contagious disease. The HSV-1 strain generally appears in the orafacial organs. All herpes viruses are morphologically identical: they have a large double stranded DNA genome, and the virion consists of an icosahedral nucleocapsid which is surrounded by a lipid bilayer envelope. Following primary infection, the virus establishes a latent infection in the host and may reactivate at any stage. Reactivation is frequently, but not always, associated with further disease. Infected cell protein 10 (ICP10) represents the large subunit of the HSV-2 ribonucleotide reductase (RR). ICP10 is made up of a serine/threonine protein kinase domain at the amino-terminus and an RR domain at the carboxy-terminus. ICP10 may increase ras activity, and its transmembrane segment plays an important role in transformation-related signaling pathways.