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p-SMC1 Anticuerpo(4H374): sc-71790

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(Basado en el análisis de datos)
  • p-SMC1 Antibody (4H374) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against a synthetic phosphopeptide corresponding to amino acids 951-962 of human p-SMC1
  • recommended for detection of Ser 957 phosphorylated SMC1 of human origin by WB and IF; may minimally cross-react with the nonphosphorylated epitope
 

Ver tambiénSMC AntibodiesincluyebdoSMC, SMC1, SMC1 alpha, SMC1 beta, SMC2, SMC3, SMC4, SMC5, SMC6ySMC7.

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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
p-SMC1 Antibody (4H374) sc-71790 200 µg/ml $279
 Lisado de células para control positivo de Western Blot (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
HeLa nuclear extract sc-2120 250 µg/0.05 ml $143
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano SMC1B 27127 22q13.31 NM_148674 Q8NDV3
 608685
 

The SMC (structural maintenance of chromosomes) family of proteins form heterodimeric complexes that modulate sister chromatid cohesion and chromosome condensation for mitosis. The two distinct classes of SMC protein complexes are comprised of SMC1 (also designated SB1.8) along with SMC3 (also designated HCAP for human chromosome-associated protein or Bama-can), and SMC2 (also designated hCAP-E) along with SMC4 (also designated hCAP-C). The SMC1/SMC3 complex is required for metaphase progression in mitotic cells and functions independently of the SMC2/SMC4 complex during the cell cycle. SMC1 is ubiqitiously expressed in various human tissues, including thymus, testis and colon. SMC3 is expressed as a nuclear protein in the colon, but can also occur as a secreted proteoglycan (called Bamacan) which is expressed in testis and brain. Bamacan contains several glycosylation sites and is thought to play a role in basement membrane physiology.