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MAGE-D4/MAGE-D4B (H-188) Anticuerpo: sc-68851

 |  Panfleto informativo:
  • rabbit polyclonal IgG, 200µg/ml
  • epitope corresponding to amino acids 23-310 mapping near the N-terminus of MAGE-D4 of human origin
  • recommended for detection of MAGE-D4 and MAGE-D4B of human origin by WB, IP, IF and ELISA
 
Adicional MAGE Isotipos del anticuerpo ...
 
Información sobre pedidos
Productos Recomendados para Ayudar:
(Haga clic en el botón para el applicación de su selección)
WB   IP   IF   ARNic  
 
Especie Nombre del Gen Identificacion del Gen Ubicacion del cromosoma Numero de Accesion de Isoforma (ARNm) Numero de Accesion de la Proteina Número de pedido:
Humano MAGED4 728239 Xp11.22 XM_001127104, XM_001127128, XM_001127143, XM_001127150 NP_001092270
 
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 Información sobre pedidos
Descripción del productoNúmero de catálogoUnidadPrecioCantidadSumarFavorites
MAGE-D4/MAGE-D4B (H-188) sc-68851 200 µg/ml $279
 Silenciadores de Genes siRNA (click product name for more information)
Descripción del productoNúmero de catálogoUnidadPrecioCantidadSumarFavorites
MAGE-D4 siRNA (h) sc-106191 10 µM $258
MAGE-D4 (h)-PR sc-106191-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Descripción del productoNúmero de catálogoUnidadPrecioCantidadSumarFavorites
MAGE-D4 shRNA Plasmid (h) sc-106191-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Descripción del productoNúmero de catálogoUnidadPrecioCantidadSumarFavorites
MAGE-D4 shRNA (h) Lentiviral Particles sc-106191-V 200 µl $625

MAGE-D4/MAGE-D4B Background Information
MAGE-D4 (Melanoma-associated antigen D4, MAGE-E1 antigen) and MAGE-D4B (Melanoma-associated antigen D4B) are 741 amino acid proteins encoded by the human gene MAGED4 and MAGED4B, respectively. Genes of the MAGE family direct the expression of tumor antigens that are recognized on human melanomas by autologous cytolytic T lymphocytes. MAGE-D4/MAGE-D4B are believed to be glioma-specific members of MAGE family. Among cancer cells, only in glioma cells are both isoforms of MAGE-D4/MAGE-D4B specifically expressed. Among normal tissues, MAGE-D4/MAGE-D4B are expressed only in brain and ovary. Although MAGE-D4/MAGE-D4B are expressed at high levels in malignant tumors as compared to normal tissue, MAGE-D4/MAGE-D4B protein expression is not considered to be of prognostic significance.