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p21 Anticuerpo(F-5): sc-6246

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(Basado en el análisis de datos)

  • p21 Antibody (F-5) is a mouse monoclonal IgG2b provided at 200 µg/ml
  • raised against amino acids 1-159 representing full length p21 of mouse origin
  • recommended for detection of p21 of mouse, rat and human origin by WB, IP, IF, IHC(P), FCM and ELISA
  • agarose conjugate for IP studies, sc-6246 AC, 500 µg/0.25 ml agarose
  • phycoerythrin conjugate for intracellular FCM, sc-6246 PE, 100 tests
  • fluorescein (sc-6246 FITC) and rhodamine (sc-6246 TRITC) conjugates for immunofluorescence, 200 µg/1 ml
  • Alexa Fluor® 405 (sc-6246 AF405), Alexa Fluor® 488 (sc-6246 AF488) and Alexa Fluor® 647 (sc-6246 AF647) conjugates for immunofluorescence; 100 µg/2 ml
  • See 336 citations for p21 Anticuerpo (F-5)
 

Ver tambiénp21 Antibodies.

También verp21 Activators for functional analysis of cellular responses to p21.


Información sobre pedidosMenciones del ProductoInformación del gen
Productos Complementarios Recomendados:
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WB   IP   IF   IHC(P)   FCM   siRNA  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
p21 Antibody (F-5) sc-6246 200 µg/ml $279
p21 Antibody (F-5) AC sc-6246 AC 500 µg/ml, 25% ag $366
p21 Antibody (F-5) Alexa Fluor® 405 sc-6246 AF405 100 µg/2 ml $314
p21 Antibody (F-5) Alexa Fluor® 488 sc-6246 AF488 100 µg/2 ml $314
p21 Antibody (F-5) Alexa Fluor® 647 sc-6246 AF647 100 µg/2 ml $314
p21 Antibody (F-5) FITC sc-6246 FITC 200 µg/ml $282
p21 Antibody (F-5) PE sc-6246 PE 100 tests in 2 ml $303
p21 Antibody (F-5) TRITC sc-6246 TRITC 200 µg/ml $282
 Silenciadores de Genes siRNA (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
p21 siRNA (h) sc-29427 10 µM $258
p21 siRNA (m) sc-29428 10 µM $258
p21 siRNA (r) sc-108036 10 µM $258
p21 siRNA (m2) sc-44271 10 µM $258
p21 (h)-PR sc-29427-PR 10 µM, 20 µl $23
p21 (m)-PR sc-29428-PR 10 µM, 20 µl $23
p21 (r)-PR sc-108036-PR 10 µM, 20 µl $23
p21 (m2)-PR sc-44271-PR 10 µM, 20 µl $23
 Plásmidos shRNA (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
p21 shRNA Plasmid (h) sc-29427-SH 20 µg $520
p21 shRNA Plasmid (m) sc-29428-SH 20 µg $520
p21 shRNA Plasmid (r) sc-108036-SH 20 µg $520
p21 shRNA Plasmid (m2) sc-44271-SH 20 µg $520
 shRNA partículas antivirales (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
p21 shRNA (h) Lentiviral Particles sc-29427-V 200 µl $625
p21 shRNA (m) Lentiviral Particles sc-29428-V 200 µl $625
p21 shRNA (r) Lentiviral Particles sc-108036-V 200 µl $625
p21 shRNA (m2) Lentiviral Particles sc-44271-V 200 µl $625
 Lisado de células para control positivo de WB (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
KNRK nuclear extract sc-2141 250 µg/0.05 ml $143
C32 nuclear extract sc-2136 250 µg/0.05 ml $143
C32 + PMA nuclear extract sc-2137 250 µg/0.05 ml $143
C32 Whole Cell Lysate sc-2205 500 µg/200 µl $104
p21 (m): 293T Lysate sc-122305 100 µg/200 µl $205
HeLa nuclear extract sc-2120 250 µg/0.05 ml $143
MDA-MB-231 Cell Lysate sc-2232 500 µg/200 µl $104
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano CDKN1A 1026 6p21.31 NM_000389, NM_078467 P38936
 116899
Ratón Cdkn1a 12575 17 A3.3 P39689
 No Disponible
 

It is now well established that cyclins play a positive role in promoting cell cycle transitions via their ability to associate with and activate their cognate cyclin-dependent kinases (Cdks). Cdk2 associates with cyclins A, D and E, and has been implicated in the control of the G1 to S phase transition in mammals. A novel Cdk-interacting protein, designated p21, Cip1 or WAF1, has been identified in cyclin A, cyclin D1, cyclin E and Cdk2 immunoprecipitates. p21 is a potent, tight-binding inhibitor of Cdks and can inhibit the phosphorylation of Rb by cyclin A-Cdk 2, cyclin E-Cdk2, cyclin D1-Cdk4 and cyclin D2-Cdk4 complexes. Expression of p21 is inducible by wildtype, but not mutant, p53. The mouse homolog of p21 is designated CAP20.

p21 Antibody (F-5) Menciones del Producto
Vea como otros han usado anticuerpos %catalog_number% y/o anticuerpos conjugados p21 (F-5).


336 menciones totales
Cargando las citaciones
 
p21 Antibody (F-5) Data
Haga click en la imágen para agrandarla
sc-6246
p21 (F-5): sc-6246. Western blot analysis of p21 expression in KNRK (A) and C32 (B) nuclear extracts.
sc-6246
p21 (F-5): sc-6246. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing nuclear staining of select cells (A). Immunofluorescence staining of methanol-fixed knrk cells showing nuclear localization (B).
sc-6246
p21 (F-5): sc-6246. Western blot analysis of p21 expression in HeLa nuclear extract.
sc-6246
p21 (F-5): sc-6246. Western blot analysis of p21 expression in non-transfected 293T: sc-117752 (A), mouse p21 transfected 293T: sc-122305 (B) and C32 (C) whole cell lysates.
sc-6246
p21 (F-5) PE: sc-6246 PE. Intracellular FCM analysis of fixed and permeabilized C32 cells. Black line histogram represents the isotype control, normal mouse IgG2b: sc-2868.
sc-6246
p21 (F-5): sc-6246. Western blot analysis of p21 expression in untreated (A) and Doxorubicin HCl (Adriamycin) (sc-200923) treated (B) HCT 116 whole cell lysates. Note upregulation of p21 expression in lane B.
sc-6246
p21 (F-5): sc-6246. Western blot analysis of p21 expression in untreated (A) and Tenovin-1 (sc-222342) treated (B) MCF7 whole cell lysates. Note upregulation of p21 expression in lane B.
sc-6246
p21 (F-5): sc-6246. Western blot analysis of p21 expression in untreated (A) and Cyclopamine (sc-200929) treated (B) SW480 whole cell lysates. Note upregulation of p21 expression in lane B.
sc-6246
p21 (F-5): sc-6246. Western blot analysis of p21 expression in untreated (A) and SN 38 (sc-203697) treated (B) HCT 116 whole cell lysates. Note upregulation of p21 expression in lane B.
sc-6246
p21 (F-5): sc-6246. Western blot analysis of p21 expression in untreated (A) and Sodium Phenylbutyrate (sc-200652) treated (B) Hep G2 whole cell lysates. Note upregulation of p21 expression in lane B.
sc-6246
p21 (F-5): sc-6246. Western blot analysis of p21 expression in untreated (A) and Novobiocin Sodium (U-6591) (sc-358734) treated (B) T-47D whole cell lysates. Note down regulation of p21 expression in lane B.
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