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SSEA-4 Anticuerpo(MC813): sc-59368

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(Basado en el análisis de datos)
  • SSEA-4 Antibody (MC813) is a mouse monoclonal IgG3 provided at 200 µg/ml
  • raised against embryonal carcinoma cell line 2102Ep of human origin
  • recommended for detection of SSEA-4 expressed upon the surface of human teratocarcinoma stem cells (EC), human embryonic germ cells (EG) and human embryonic stem cells (ES) of mouse and human origin by IF and FCM; non cross-reactive with undifferentiated murine EC, ES and EG cells
  • See 1 citations for SSEA-4 Anticuerpo (MC813)
 

Ver tambiénSSEA AntibodiesincluyebdoSSEA, SSEA-1, SSEA-3ySSEA-4.

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SSEA-4 Antibody (MC813) sc-59368 200 µg/ml $279

Embryonic stem cells have the ability to remain undifferentiated and proliferate indefinitely in vitro, while maintaining the potential to differentiate into derivatives of all three embryonic germ layers (1). Undifferentiated human embryonal carcinoma (EC) cells are the stem cells of teratocarcinomas (2) and are characterized by the expression of Stage Specific Embryonic Antigens SSEA-1 and SSEA-3, TRA-2-39, TRA-2-54 and the high molecular weight glycoproteins TRA-1-60 and TRA-1-81 (3). In addition, SSEA-1, SSEA-3 and SSEA-4 are markers that characterize embryonic stem (ES) and embryonic germ (EG) cells (4). Specifically, undifferentiated cells from the human ES cell line H7 express SSEA-3, SSEA-4, TRA-1-60 and TRA-1-81, but not SSEA-1 (5). Interferon induces expression of SSEA-3 and SSEA-4 in EC cells without inhibiting their growth or inducing their differentiation (2).

SSEA-4 Antibody (MC813) Menciones del Producto
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