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HSV-1 gC Envelope Protein Anticuerpo(1.B.36): sc-57844

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  • HSV-1 gC Envelope Protein Antibody (1.B.36) is a mouse monoclonal IgG2 provided at 100 µg/ml
  • raised against Herpes Virus
  • recommended for detection of glycoprotein C envelope protein of Herpes Simplex Virus 1 origin by WB and IF
 

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HSV-1 gC Envelope Protein Antibody (1.B.36) sc-57844 100 µg/ml $279


Herpes simplex virus 1 (HSV-1) is a member of the Herpesviridae family of DNA viruses that have relatively large double-stranded, linear genomes within an icosahedral capsid which is wrapped in a lipid bilayer envelope. HSV-1 causes painful, watery blisters in the skin and/or mucous membranes of infected individuals. The disease is contagious, particularly during an outbreak, and is transmitted by direct contact. When not symptomatic, HSV-1 lies dormant in the bodies of the nerve cells, replicating within the axons towards the skin. HSV-1 glycoprotein C (HSV-1 gC) is an immune evasion molecule that binds to and inhibits the complement component C3b, thereby protecting the virus from complement-mediated neutralization. HSV-1 gC also enhances coagulation Factor VIIa activity on the virus, which activates Factor X.