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TIP60 Anticuerpo(N-17): sc-5725

 |  Ficha Técnica

(Basado en el análisis de datos)

  • TIP60 Antibody (N-17) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the N-terminus of TIP60 of human origin
  • recommended for detection of TIP60 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
  • blocking peptide, sc-5725 P
  • TransCruz reagent for ChIP application, sc-5725 X, 200 µg/0.1 ml
  • See 14 citations for TIP60 Anticuerpo (N-17)
 

Ver tambiénTIP60 Antibodies.

Información sobre pedidosMenciones del ProductoInformación del gen
Productos Complementarios Recomendados:
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WB   IP   IF   ChIP   siRNA  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
TIP60 Antibody (N-17) sc-5725 200 µg/ml $279
TIP60 (N-17) P sc-5725 P
(peptide)
100 µg/0.5 ml $61
TIP60 Antibody (N-17) X sc-5725 X 200 µg/0.1 ml $279
 Silenciadores de Genes siRNA (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
TIP60 siRNA (h) sc-37966 10 µM $258
TIP60 siRNA (m) sc-37967 10 µM $258
TIP60 (h)-PR sc-37966-PR 10 µM, 20 µl $23
TIP60 (m)-PR sc-37967-PR 10 µM, 20 µl $23
 Plásmidos shRNA (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
TIP60 shRNA Plasmid (h) sc-37966-SH 20 µg $520
TIP60 shRNA Plasmid (m) sc-37967-SH 20 µg $520
 shRNA partículas antivirales (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
TIP60 shRNA (h) Lentiviral Particles sc-37966-V 200 µl $625
TIP60 shRNA (m) Lentiviral Particles sc-37967-V 200 µl $625
 Lisado de células para control positivo de WB (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
SK-BR-3 nuclear extract sc-2134 250 µg/0.05 ml $143
KNRK nuclear extract sc-2141 250 µg/0.05 ml $143
IMR-32 nuclear extract sc-2148 250 µg/0.05 ml $143
TIP60 (m): 293T Lysate sc-124076 100 µg/200 µl $205
Jurkat nuclear extract sc-2132 250 µg/0.05 ml $143
CCRF-CEM nuclear extract sc-2146 250 µg/0.05 ml $143
TIP60 (h): 293T Lysate sc-110591 100 µg/200 µl $205
TIP60 (h2): 293T Lysate sc-117021 100 µg/200 µl $205
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano HTATIP 10524 11q13.1 NM_006388, NM_182709, NM_182710 Q92993
601409
Ratón Htatip 81601 19 A Q8CHK4
No Disponible
 


MOZ (monocytic leukemia zinc finger protein) is a chromatin-associated histone acetyltransferase (HAT) that regulates chromatin remodeling and transcription. The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional coactivator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ related proteins, including MORF (MOZ related factor) and TIP60 (TAT interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. MORF also contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at the C terminus, suggesting that MORF has both HAT activity and contributes to the regulation of transcriptional activation. TIP60 was originally identified as a coactivator for the HIV TAT protein and also functions as a nuclear hormone receptor coactivator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors.

TIP60 Antibody (N-17) Menciones del Producto
Vea como otros han usado anticuerpos %catalog_number% y/o anticuerpos conjugados TIP60 (N-17).


14 menciones totales
Cargando las citaciones
 
TIP60 Antibody (N-17) Data
Haga click en la imágen para agrandarla
TIP60 (N-17): sc-5725. Western blot analysis of TIP60 expression in SK-BR-3 (A), KNRK (B) and IMR-32 (C) nuclear extracts.
ChIP analysis of coactivator recruitment on Cyclin D2 promoter in C2C12 cells treated with LiCl and serum. Antibodies tested include β-catenin (H-102): sc-7199, β-catenin (C-18): sc-1496, β-catenin (E-5): sc-7963, Tip60 (N-17): sc-5725, TRRAP (T-17): sc-5405, TRRAP (Y-18): sc-12375, TRRAP (F-20): sc-12376, TRRAP (H-300): sc-11411, CBP (A-22): sc-369, CBP (C-20): sc-583, CBP (451): sc-1211, CPB (C-1): sc-7300, p300 (H-272): sc-8981, p300 (N-15): sc-584 and p300 (C-20): sc-585. Data kindly provided by M.G. Rosenfeld and reproduced with permission from Kioussi et al., Cell 2002, 111: 673-685.
ChIP analysis of in vivo binding of RORα and its recruitment of coactivators to RORα-responsive promoters in freshly dissected cerebella derived from wild type (+/+) and staggerer (Sg) mice. Control Input (A). Antibodies used included RORα (C-16): sc-6062 (B), TIP60 (N-17): sc-5725 (C), CBP (A-22): sc-369 and CBP (C-20): sc-583 (D). Data kindly provided by M.G. Rosenfeld and reproduced wtih permission from Gold et al., Neuron 2003, 40: 1119-1131.
ChIP analysis of in vivo binding of RORα and its recruitment of coactivators to RORα-responsive promoters in freshly dissected cerebella derived from wild type (+/+) and staggerer (Sg) mice. Control Input (A). Antibodies used included RORα (C-16): sc-6062 (B), TIP60 (N-17): sc-5725 (C), CBP (A-22): sc-369 and CBP (C-20): sc-583 (D). Data kindly provided by M.G. Rosenfeld and reproduced wtih permission from Gold et al., Neuron 2003, 40: 1119-1131.
ChIP analysis of in vivo binding of RORα and its recruitment of coactivators to RORα-responsive promoters in freshly dissected cerebella derived from wild type (+/+) and staggerer (Sg) mice. Control Input (A). Antibodies used included RORα (C-16): sc-6062 (B), TIP60 (N-17): sc-5725 (C), CBP (A-22): sc-369 and CBP (C-20): sc-583 (D). Data kindly provided by M.G. Rosenfeld and reproduced wtih permission from Gold et al., Neuron 2003, 40: 1119-1131.
TIP60 (N-17): sc-5725. Western blot analysis of TIP60 expression in non-transfected: sc-117752 (A) and mouse TIP60 transfected: sc-124076 (B) 293T whole cell lysates.
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