HA-Tag Antibody (153): sc-53516

HA-Tag Antibody (153) is a rat monoclonal IgG2a antibody raised against the HA peptide, derived from the influenza hemagglutinin protein. The HA-tag, an 11 amino acid sequence, is commonly fused to proteins of interest for purification, detection, and localization studies in various systems, including bacterial, insect, and mammalian cells. Cellular localization of HA-tagged proteins is crucial for understanding biological functions, as location often determines interactions, roles in signaling pathways, and participation in cellular processes. HA-Tag (153) antibody enables detection of these proteins, whether localized in the cytoplasm, nucleus, or membranes, helping researchers explore dynamic cellular events. Hemagglutinin itself plays a role in viral entry by binding to host cell membranes, and its structure ensures accessibility of the HA-tag′s specific epitope. This specificity allows visualization and tracking of tagged proteins in applications like immunohistochemistry with paraffin-embedded sections (IHCP) and immunofluorescence (IF), which depend on identifying exact cellular compartments where proteins reside. Such studies are essential for elucidating protein function and mechanisms regulating cellular processes. HA-Tag (153) monoclonal antibody is available in both non-conjugated and conjugated forms, providing flexibility for diverse experimental designs in protein research.

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The preferred HA-Tag antibody is HA-Tag Antibody (F-7): sc-7392.