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osteocalcin Anticuerpo(E-6): sc-376835

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(Basado en el análisis de datos)
  • osteocalcin Antibody (E-6) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 41-79 within an internal region of osteocalcin of mouse origin
  • recommended for detection of osteocalcin proteins OG1, OG2 and ORG of mouse origin by WB, IP, IF and ELISA
 

Ver tambiénosteocalcin Antibodies.

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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
osteocalcin Antibody (E-6) sc-376835 200 µg/ml $279
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Ratón Bglap-rs1 12095 3 F1 NM_031368 P54615
 No Disponible
Ratón Bglap1 12096 3 F1 NM_001037939, NM_007541 P04641
 No Disponible
Ratón Bglap2 12097 3 F1 NM_001032298 P04641
 No Disponible
 

Bone g-carboxyglutamic acid (Gla) protein, known as BGLAP, BGP or osteocalcin, is an abundant, non-collagenous protein component of bone that is produced by osteoblasts. In mice, osteocalcin is composed of a cluster of 3 genes known as OG1, OG2 and ORG, all of which can be found within a 23Kb span of genomic DNA. Human osteocalcin is a highly conserved, 46-50 amino acid, single chain protein that contains three vitamin K-dependent g-carboxyglutamic acid residues. Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner. In addition, osteocalcin is one of the most abundant, non-collagenous proteins found in mineralized adult bone. Genetic variation at the osteocalcin locus on chromosome 1q impacts postmenopause bone mineral density (BMD) levels and may predispose some women to osteoporosis.
osteocalcin Antibody (E-6) Data
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sc-376835
osteocalcin (E-6): sc-376835. Western blot analysis of mouse recombinant osteocalcin fusion protein.
sc-376835
osteocalcin (E-6): sc-376835. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoplasmic localization.
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