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TGFα Anticuerpo(D-6): sc-374433

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(Basado en el análisis de datos)

  • TGFα Antibody (D-6) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 63-89 at the C-terminus of TGFå of human origin
  • recommended for detection of presursor and mature TGFα and BTC of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
 

Ver tambiénTGF AntibodiesincluyebdoTGF, TGF alpha, TGF beta, TGF beta 1, TGF beta 2yTGF beta 3.

También verTGF Inhibitors for functional analysis of cellular responses to TGF.


Información sobre pedidosInformación del gen
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WB   IP   IF   IHC(P)  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
TGFα Antibody (D-6) sc-374433 200 µg/ml $279
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano BTC 685 4q13.3 NM_001729 P35070
 600345
Humano TGFA 7039 2p13.3 NM_001099691, NM_003236 P01135
 190170
Ratón Btc 12223 5 E2 NM_007568 Q05928
 No Disponible
Ratón Tgfa 21802 6 D1 NM_031199 P48030
 No Disponible
 

Transforming growth factor-å (TGFå) is an acid- and heat-stable 50 amino acid protein originally found in rodents and humans. TGFå is 33% homologous at the amino acid level to epidermal growth factor (EGF). TGFå binds to the EGF receptor, mediates tyrosine phosphorylation of the receptor and promotes anchorage-independent growth of normal rat fibroblasts in soft agar in the presence of transforming growth factor-∫. TGFa is secreted by a variety of transformed cells and tumors, embryonic cells and some normal adult cells. TGFå bioactivity has been found in the urine of cancer patients. It has been suggested that it may act as an autocrine growth factor for the induction or maintenance of malignancy.
TGFα Antibody (D-6) Data
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sc-374433
TGFα (D-6): sc-374433. Western blot analysis of TGFα expression in non-transfected (A) and human TGFα transfected (B) 293T whole cell lysates.
sc-374433
TGFα (D-6): sc-374433. Western blot analysis of human recombinant TGFα fusion protein.
sc-374433
TGFα (D-6): sc-374433. Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart muscle tissue showing cytoplasmic staining of myocytes.
sc-374433
TGFα (D-6): sc-374433. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.
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