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NC2α Anticuerpo(H-3): sc-374336

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(Basado en el análisis de datos)

  • NC2α Antibody (H-3) is a mouse monoclonal IgM provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 47-82 within an internal region of NC2α of human origin
  • recommended for detection of NC2α of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-374336 X, 200 µg/0.1 ml
 

Ver tambiénNC2 alpha Antibodies.

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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
NC2α Antibody (H-3) sc-374336 200 µg/ml $279
NC2α Antibody (H-3) X sc-374336 X 200 µg/0.1 ml $279
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano DRAP1 10589 11q13.1 NM_006442 Q14919
 602289
 

NC2 (negative cofactor 2) is a dimeric histone-fold complex that represses RNA polymerase II transcription through binding to TBP and inhibiting the transcription factors TFIIA and TFIIB. NC2 consists of two subunits, termed NC2å and NC2∫, and these subunits dimerize and bind to TBP-promoter complexes via histone fold domains of the H2A-H2B type. NC2 associates with promoters in a manner that correlates with transcriptional activity and with occupancy by basal transcription factors. NC2 binds directly to DNA, and the binding of NC2 to TBP-promoter complexes affects the conformation of DNA, and results in the inhibition of TFIIB.
NC2α Antibody (H-3) Data
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sc-374336
NC2α (H-3): sc-374336. Western blot analysis of NC2α expression in MIA PaCa-2 whole cell lysate.
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