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CapZ-α Anticuerpo(H-9): sc-374302

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(Basado en el análisis de datos)

  • CapZ-α Antibody (H-9) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against amino acids 157-286 mapping at the C-terminus of CapZα1 of human origin
  • recommended for detection of CapZ-α1 and CapZ-α2 of human origin by WB, IP, IF, IHC(P) and ELISA
 
Secuencia completa de la proteína para CapZ-α con inmunógeno inidcado:
MADFDDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEADGGLKSWRESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSLTVSNEAQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA

Ver tambiénCapZ AntibodiesincluyebdoCapZ, CapZ-α2, CapZ-alpha, CapZ-alpha 1, CapZ-betayCapZ-alpha 3.

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WB   IP   IF   IHC(P)  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
CapZ-α Antibody (H-9) sc-374302 200 µg/ml $279
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano CAPZA1 829 1p13.2 NM_006135 P52907
 601580
Humano CAPZA2 830 7q31.2 NM_006136 P47755
 601571
Ratón Capza1 12340 3 F2.2 NM_009797 P47753
 No Disponible
Ratón Capza2 12343 6 A2 NM_007604 P47754
 No Disponible
 

The F-Actin family of capping proteins includes CapZ-å1, CapZ-å2, CapZ-å3 and CapZ-∫3, all of which function in a calcium-dependent manner and bind to the fast growing barbed end of Actin filaments, thereby blocking protein exchange at these ends. The F-Actin capping protein complex is a heterodimer consisting of å and ∫ subunits that caps the barbed ends of Actin filaments and nucleates the polymerization of Actin monomers, yet does not sever Actin filaments. CapZ-å1, also known as F-Actin-capping protein subunit alpha-1, is a 286 amino acid subunit of the heterodimer that forms the F-Actin capping protein complex. CapZ-å1 also has been shown to bind S-100 ∫ chain, a signaling molecule involved in the calcium-sensitive assembly of intermediate filaments that has been linked to Alzheimer’s disease.

CapZ-α Antibody (H-9) Data
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sc-374302
CapZ-α (H-9): sc-374302. Western blot analysis of CapZ-α expression in HeLa (A) and Jurkat (B) whole cell lysates.
sc-374302
CapZ-α (H-9): sc-374302. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
sc-374302
CapZ-α (H-9): sc-374302. Immunoperoxidase staining of formalin fixed, paraffin-embedded human spleen tissue showing cytoplasmic staining of cells in white and red pulps.
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