ELOVL5 Anticuerpo(B-3): sc-374138

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Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 5 (ELOVL5), also known as HELO1 (human elongase 1), is predominantly expressed in adrenal gland and testis, but is also found in lung, brain and prostate tissue. ELOVL5 participates in the elongation of monounsaturated and polyunsaturated fatty acids of 18 to 20 carbons and thereby regulates the activity of PPARå. In addition, ELOVL5 localizes to the sebaceous glands of the pheromone-producing region of skin and may be associated with pheromone production and regulation.