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IRF-2BP1 Anticuerpo(A-10): sc-373899

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(Basado en el análisis de datos)

  • IRF-2BP1 Antibody (A-10) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 327-355 within an internal region of IRF-2BP1 of human origin
  • recommended for detection of IRF-2BP1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-373899 X, 200 µg/0.1 ml
 

Ver tambiénIRF-2BP AntibodiesincluyebdoIRF-2BP2, IRF-2BP1yIRF-2BP.

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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
IRF-2BP1 Antibody (A-10) sc-373899 200 µg/ml $279
IRF-2BP1 Antibody (A-10) sc-373899 X 200 µg/0.1 ml $279
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano IRF2BP1 26145 19q13.33 NM_015649 Q8IU81
 n/a
Ratón Irf2bp1 272359 7 A3 NM_178757 Q8R3Y8
 No Disponible
 

IRF-2 (interferon regulatory factor-2) has been identified as a novel DNA-binding factor that functions as a regulator of both type I interferon (interferon-å and ∫) and interferon-inducible genes. IRF-2 may act in a mutually antagonistic manner in regulating cell growth. IRF-2BP1 (interferon regulatory factor 2 binding protein 1) is a 584 amino acid nuclear protein belonging to the IRF-2BP family. IRF-2BP1 acts as a corepressor of IRF-2 that can inhibit both enhancer-activation and basal transcription in a manner that is not dependent upon histone deacetylation. IRF-2BP1 enhances the polyubiquitination of JDP2 (Jun-dimerization protein 2), a member of the c-Jun family of transcription factors. IRF-2BP1 contains a C-terminal RING-type zinc finger domain, which is necessary for interaction with BAP1 (BRCA1 associated protein 1). IRF-2BP1 is encoded by a gene located on human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.
IRF-2BP1 Antibody (A-10) Data
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sc-373899
IRF-2BP1 (A-10): sc-373899. Western blot analysis of IRF-2BP1 expression in non-transfected: sc-117752 (A) and human IRF-2BP1 transfected: sc-111584 (B) 293T whole cell lysates.
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