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p-Met Anticuerpo(Tyr 1313): sc-34085

 |  Ficha Técnica

(Basado en el análisis de datos)
  • p-Met Antibody (Tyr 1313) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to phosphorylated Tyr 1313 of Met of human origin
  • recommended for detection of Tyr 1313 phosphorylated Met of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-34085 P
  • See 2 citations for p-Met Anticuerpo (Tyr 1313)
 

Ver tambiénMet Antibodies.

También verMet Inhibitors for functional analysis of cellular responses to Met.


Información sobre pedidosMenciones del ProductoInformación del gen
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
p-Met Antibody (Tyr 1313) sc-34085 200 µg/ml $279
p-Met (Tyr 1313) P sc-34085 P
(peptide)
 100 µg/0.5 ml $61
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano MET 4233 7q31.2 NM_000245 P08581
 611015
Ratón Met 17295 6 A2 P16056
 No Disponible
 

The c-Met oncogene was originally isolated from a chemical carcinogen-treated human osteogenic sarcoma cell line by transfection analysis in NIH/3T3 cells. The Met proto-oncogene product was identified as a transmembrane receptor-like protein with tyrosine kinase activity that is expressed in many tissues. A high proportion of spontaneous NIH/3T3 transformants overexpress c-Met and by transfection analysis the c-Met proto-oncogene has been shown to exhibit transforming activity.Tyrosine phosphorylation of apparently normal Met protein has also been observed in certain human gastric carcinoma cell lines. Tyrosine phosphorylation enhances the receptor kinase activity, while serine phosphorylation of Met on residue 985 has an inhibitory effect. The c-Met gene product has been identified as the cell surface receptor for hepatocyte growth factor, a plasminogen-like protein thought to be a humoral mediator of liver regeneration.

p-Met Antibody (Tyr 1313) Menciones del Producto
Vea como otros han usado anticuerpos %catalog_number% y/o anticuerpos conjugados p-Met (Tyr 1313).


2 menciones totales
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