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Página Principal » Químicos » Project-Id-Version: Report-Msgid-Bugs-To: POT-Creation-Date: 2013-05-13 21:34-0800 PO-Revision-Date: Last-Translator: M Language-Team: Language: es_US MIME-Version: 1.0 Content-Type: text/plain; charset=UTF-8 Content-Transfer-Encoding: 8bit X-Poedit-Basepath: /Library/WebServer/Documents/ X-Poedit-SourceCharset: UTF-8 X-Poedit-Bookmarks: -1,-1,719,-1,-1,-1,-1,-1,-1,-1 X-Generator: Poedit 1.5.3 X-Poedit-SearchPath-0: www.scbt.com W140 trifluoroacetate salt: sc-296699

W140 trifluoroacetate salt

Peso Molecular:456.4
Fórmula Molecular:C16H27N2O4P•C2F3HO2
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
W140 trifluoroacetate salt sc-296699 500 µg $82
W140 trifluoroacetate salt sc-296699A 1 mg $157
Descripción
Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. W140 (trifluoroacetate salt) is an inactive enantiomer of W146, a selective S1P1 antagonist (Ki = 77 nM), that binds to the S1P1 receptor with a Ki of 4.6 µM (2a = W146; 2b = W140 in supplemental material). It exhibits no biological activity in vivo and can therefore serve as an effective control compound for experiments involving W146.
Información Técnica
Apariencia:A crystalline solid
Almacenamiento:Store at -20° C
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.
SDS
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