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CRMP-5 Anticuerpo(H-85): sc-292382

 |  Ficha Técnica

(Basado en el análisis de datos)

  • CRMP-5 Antibody (H-85) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 451-535 mapping near the C-terminus of CRMP-5 of human origin
  • recommended for detection of CRMP-5 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
 
Secuencia completa de la proteína para CRMP-5 con inmunógeno inidcado:
MLANSASVRILIKGGKVVNDDCTHEADVYIENGIIQQVGRELMIPGGAKVIDATGKLVIPGGIDTSTHFHQTFMNATCVDDFYHGTKAALVGGTTMIIGHVLPDKETSLVDAYEKCRGLADPKVCCDYALHVGITWWAPKVKAEMETLVREKGVNSFQMFMTYKDLYMLRDSELYQVLHACKDIGAIARVHAENGELVAEGAKEALDLGITGPEGIEISRPEELEAEATHRVITIANRTHCPIYLVNVSSISAGDVIAAAKMQGKVVLAETTTAHATLTGLHYYHQDWSHAAAYVTVPPLRLDTNTSTYLMSLLANDTLNIVASDHRPFTTKQKAMGKEDFTKIPHGVSGVQDRMSVIWERGVVGGKMDENRFVAVTSSNAAKLLNLYPRKGRIIPGADADVVVWDPEATKTISASTQVQGGDFNLYENMRCHGVPLVTISRGRVVYENGVFMCAEGTGKFCPLRSFPDTVYKKLVQREKTLKVRGVDRTPYLGDVAVVVHPGKKEMGTPLADTPTRPVTRHGGMRDLHESSFSLSGSQIDDHVPKRASARILAPPGGRSSGIW

Ver tambiénCRMP AntibodiesincluyebdoCRMP-5, CRMP-4, CRMP-3, CRMP-2, CRMP-1yCRMP.

Información sobre pedidosInformación del gen
Productos Complementarios Recomendados:
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WB   IP   IF  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
CRMP-5 Antibody (H-85) sc-292382 200 µg/ml $279
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano DPYSL5 56896 2p23.3 NM_020134 Q9BPU6
608383
Ratón Dpysl5 65254 5 B1 NM_023047 Q9EQF6
No Disponible
 


Collapsin response mediator proteins (CRMPs), including CRMP-1 (DRP-1), CRMP-2 (DRP-2 or TOAD64), CRMP-3 (DRP-4), CRMP-4 (DRP-3) and CRMP-5 (DRP-5), mediate signal transduction after exposure of neural cells to the axon guidance molecule Semaphorin 3A (SEMA3A)/collapsin. CRMPs are present in the developing cerebral cortex and neocortical neurons and are responsive to SEMA3A. In the adult brain, the expression of CRMPs is dramatically downregulated. However, they remain expressed in structures that retain their capacity for differentiation and plasticity. CRMP-5, which is phylogenetically divergent from the other four CRMPs, is expressed in the filopodia of growth cones as well as in adult central and peripheral neurons, including synapses. The paraneoplastic CRMP-5 autoantibody (CRMP-5-IgG) is also associated with small-cell lung carcinoma or thymoma.

CRMP-5 Antibody (H-85) Data
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CRMP-5 (H-85): sc-292382. Western blot analysis of CRMP-5 expression in non-transfected: sc-117752 (A) and human CRMP-5 transfected: sc-176143 (B) 293T whole cell lysates.
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