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NRAGE (H-300) Anticuerpo: sc-28243

 |  Panfleto informativo:
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to amino acids 1-300 mapping at the N-terminus of NRAGE of human origin
  • recommended for detection of NRAGE of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
 
Adicional NRAGE Isotipos del anticuerpo ...
 
Información sobre pedidos
Productos Recomendados para Ayudar:
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WB   IP   IF   IHC(P)   ARNic  
 
Especie Nombre del Gen Identificacion del Gen Ubicacion del cromosoma Numero de Accesion de Isoforma (ARNm) Numero de Accesion de la Proteina Número de pedido:
Humano MAGED1 9500 Xp11.22 NM_001005332, NM_001005333, NM_006986 Q9Y5V3
300224
Ratón Maged1 94275 X C3 Q9QYH6
No Aplicable
 
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 Información sobre pedidos
Descripción del productoNúmero de catálogoUnidadPrecioCantidadSumarFavorites
NRAGE (H-300) sc-28243 200 µg/ml $279
 Silenciadores de Genes siRNA (click product name for more information)
Descripción del productoNúmero de catálogoUnidadPrecioCantidadSumarFavorites
NRAGE siRNA (h) sc-37320 10 µM $258
NRAGE siRNA (m) sc-45975 10 µM $258
NRAGE (h)-PR sc-37320-PR 10 µM $23
NRAGE (m)-PR sc-45975-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Descripción del productoNúmero de catálogoUnidadPrecioCantidadSumarFavorites
NRAGE shRNA Plasmid (h) sc-37320-SH 20 µg $520
NRAGE shRNA Plasmid (m) sc-45975-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Descripción del productoNúmero de catálogoUnidadPrecioCantidadSumarFavorites
NRAGE shRNA (h) Lentiviral Particles sc-37320-V 200 µl $625
NRAGE shRNA (m) Lentiviral Particles sc-45975-V 200 µl $625
 WB Control Positivo de Lysates Células (click product name for more information)
Descripción del productoNúmero de catálogoUnidadPrecioCantidadSumarFavorites
NRAGE (h): 293T Lysate sc-114826 100µg/200µl $205
mouse brain extract sc-2253 500 µg/200 µl $104
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104

NRAGE Background Information
The neurotrophin family of growth factors (NGF) function to regulate neuronal differentiation, synaptic activity and neuronal survival, as well as axonal and dendritic growth. The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. Neurotrophin receptor-interacting MAGE homolog (NRAGE) binds the p75 neurotrophin re-ceptor and associates with the plasma membrane when NGF binds p75NTR. The critical factors for NRAGE association lie within the juxtamembrane domain of p75NTR. Overexpression of NRAGE stimulates cell cycle arrest and allows NGF-dependent apoptosis within sympathetic neuron precursors cells. NRAGE is expressed in the medulla oblongata during development and motor-neurons. Structural similarities suggest NRAGE, and the MAGE protein necdin, (Ndn), mediate cell cycle effects through a shared mechanism.

NRAGE (H-300)
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NRAGE (H-300): sc-28243. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
NRAGE (H-300): sc-28243. Western blot analysis of NRAGE expression in non-transfected: sc-117752 (A) and human NRAGE transfected: sc-114826 (B) 293T whole cell lysates.
NRAGE (H-300): sc-28243. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skin tissue showing cytoplasmic staining of adnexal and epidermal cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
NRAGE (H-300): sc-28243. Western blot analysis of NRAGE expression in mouse brain tissue extract.
NRAGE (H-300): sc-28243. Western blot analysis of NRAGE expression in mouse brain tissue extract.
NRAGE (H-300): sc-28243. Western blot analysis of NRAGE expression in non-transfected 293T: sc-117752 (A), mouse NRAGE transfected 293T: sc-122121 (B), Jurkat (C) and ALL-S1L (D) whole cell lysates.
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