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AHCYL1/2 Anticuerpo(D-7): sc-271581

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(Basado en el análisis de datos)

  • AHCYL1/2 Antibody (D-7) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against amino acids 1-160 mapping at the N-terminus of AHCYL1 of human origin
  • recommended for detection of AHCYL1 and AHCYL2 of m and h origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, bovine and porcine
 
Secuencia completa de la proteína para AHCYL1/2 con inmunógeno inidcado:
MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTALIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY

Ver tambiénAHCYL AntibodiesincluyebdoAHCYL, AHCYL1yAHCYL2.

Información sobre pedidosInformación del gen
Productos Complementarios Recomendados:
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WB   IP   IF   IHC(P)  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
AHCYL1/2 Antibody (D-7) sc-271581 200 µg/ml $279
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano AHCYL1 10768 1p13.3 NM_006621 O43865
 607826
Humano AHCYL2 23382 7q32.1 NM_001130720, NM_001130722, NM_001130723, NM_015328 NP_056143
 n/a
Ratón Ahcyl2 74340 6 A3.3 NM_001171000, NM_001171001, NM_021414 Q68FL4
 No Disponible
Ratón Ahcyl1 229709 3 F2.3 NM_145542 Q80SW1
 No Disponible
 

AHCYL1 (S-adenosylhomocysteine hydrolase-like 1), also known as DCAL, IRBIT or PRO0233, and AHCYL2 (S-adenosylhomocysteine hydrolase-like 2) are endoplasmic reticulum (ER) proteins involved in amino acid biosynthesis. Expressed in dentritic blood cells (DCs), AHCYL1 and AHCYL2 function to catalyze the H(2)O-dependent conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine, a reaction that uses NAD as a cofactor. Additionally, AHCYL1 contains a PDZ-binding domain and a PEST region through which it can interact with IP3R-I (inositol 1,4,5-trisphosphate (IP3) receptor-I), a protein involved in various signaling pathways. This interaction lowers the affinity of IP3R-1 for its substrate, IP3, thereby decreasing the rate of IP3-IP3R-I binding.

AHCYL1/2 Antibody (D-7) Data
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sc-271581
AHCYL1/2 (D-7): sc-271581. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
sc-271581
AHCYL1/2 (D-7): sc-271581. Western blot analysis of AHCYL1/2 expression in HeLa whole cell lysate.
sc-271581
AHCYL1/2 (D-7): sc-271581. Western blot analysis of AHCYL1/2 expression in ME-180 (A), HEK293 (B), Ramos (C), L-428 (D) and Hep G2 (E) whole cell lysates.
sc-271581
AHCYL1/2 (D-7): sc-271581. Western blot analysis of AHCYL1 expression in non-transfected: sc-117752 (A) and human AHCYL1 transfected: sc-127950 (B) 293T whole cell lysates.
sc-271581
AHCYL1/2 (D-7): sc-271581. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic and membrane staining of glandular cells.
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