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eIF4E Anticuerpo(A-10): sc-271480

 |  Ficha Técnica

(Basado en el análisis de datos)

  • eIF4E Antibody (A-10) is a mouse monoclonal IgG2b provided at 200 µg/ml
  • raised against amino acids 1-217 representing full length eIF4E of human origin
  • recommended for detection of eIF4E of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
 
Secuencia completa de la proteína para eIF4E con inmunógeno inidcado:
MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFV

Ver tambiéneIF AntibodiesincluyebdoeIF, eIF1, eIF1/1B, eIF1AD, eIF1AX, eIF1AY, eIF2 alpha, eIF2 beta, eIF2B alpha, eIF2B beta, eIF2B delta, eIF2B epsilon, eIF2B gamma, eIF2C, eIF2D, eIF3 alpha, eIF3 beta, eIF3 delta, eIF3 epsilon, eIF3 eta, eIF3 gamma, eIF3 theta, eIF3 zeta, eIF3e, eIF3K, eIF3M, eIF4A, eIF4AI, eIF4AII, eIF4AIII, eIF4B, eIF4E, eIF4G, eIF4GII, eIF4H, eIF5, eIF5A, eIF5B, eIF6, eIF2C1, eIF2C2, eIF2C3, eIF2S3, eIF2C4, eIF2C5, EIF3S6IP, eIF4E2, eIF4E3yeIF3 p110.

También vereIF4E Inhibitors for functional analysis of cellular responses to eIF4E.


Información sobre pedidosInformación del gen
Productos Complementarios Recomendados:
(Haga click en el botón de la aplicación que desee)
WB   IP   IF   IHC(P)  
Indique que divisas

 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
eIF4E Antibody (A-10) sc-271480 200 µg/ml $279
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano EIF4E 1977 4q23 NM_001130678, NM_001130679, NM_001968 NP_001959
133440
Ratón Eif4e 13684 3 G3 NM_007917, XM_001004193 P63073
No Disponible
 


The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4G, eIF4E, and eIF4A. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures (1,2). eIF4E binds to the mRNA “cap” during an early step in the initiation of protein synthesis (3,4). eIF4A acts as an ATP-dependent RNA helicase (5,6). eIF4G acts as a bridge between eIF4E, eIF4A, and the eIF3 complex (7,8).

eIF4E Antibody (A-10) Data
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eIF4E (A-10): sc-271480. Western blot analysis of eIF4E expression in KNRK (A) and SRC-3T3 (B) whole cell lysates.
eIF4E (A-10): sc-271480. Immunoperoxidase staining of formalin fixed, paraffin-embedded human brain tissue showing cytoplasmic staining of neuronal and glial cells.
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