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POR1 Anticuerpo(E-3): sc-271478

 |  Ficha Técnica

(Basado en el análisis de datos)

  • POR1 Antibody (E-3) is a mouse monoclonal IgG2a provided at 200 µg/ml
  • raised against amino acids 1-100 mapping at the N-terminus of POR1 of human origin
  • recommended for detection of POR1 of human origin by WB, IP, IF, IHC(P) and ELISA
 
Secuencia completa de la proteína para POR1 con inmunógeno inidcado:
MTDGILGKAATMEIPIHGNGEARQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGSGRHPSHSTTPSGPGDEVARGIAGEKFDIVKKWINTYKCTKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ

Ver tambiénPOR1 Antibodies.

Información sobre pedidosInformación del gen
Productos Complementarios Recomendados:
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WB   IP   IF   IHC(P)  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
POR1 Antibody (E-3) sc-271478 200 µg/ml $279
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano ARFIP2 23647 11p15.4 NM_012402 NP_036534
601638
Ratón Arfip2 76932 7 E3 NM_029802 Q8K221
No Disponible
 


POR1 (also designated arfaptin 2) was first isolated as a Rac 1 binding protein necessary for Rac-mediated Actin polymerization and the subsequent formation of membrane ruffles and lamellipodia. POR1 has also been shown to interact with the ADP ribosylation factor ARF6, a GTPase that associates with the plasma membrane and intracellular endosome vesicles, in a GTP dependent manner. The association of POR1 with ARF6 stimulates induction of Actin polymerization. POR1 appears to play a regulatory role through mul-tiple signaling pathways in the reorganization of the cytoskeletal structure.

POR1 Antibody (E-3) Data
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POR1 (E-3): sc-271478. Western blot analysis of POR1 expression in HeLa whole cell lysate.
POR1 (E-3): sc-271478. Immunoperoxidase staining of formalin fixed, paraffin-embedded human rectum tissue showing cytoplasmic staining of glandular cells.
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