¡Bienvenido a Santa Cruz Biotechnology!
SCBT Home
Página Principal » Factores de crecimiento y Hormonas » Neurophysin Anticuerpos » Neurophysin II Antibody (A-20): sc-27094

Neurophysin II Anticuerpo(A-20): sc-27094

 |  Ficha Técnica

(Basado en el análisis de datos)
  • Neurophysin II Antibody (A-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of Neurophysin II of human origin
  • recommended for detection of Neurophysin II of human origin by WB, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
  • blocking peptide, sc-27094 P
 

Ver tambiénNeurophysin AntibodiesincluyebdoNeurophysin, Neurophysin IyNeurophysin II.

Información sobre pedidosInformación del gen
Productos Complementarios Recomendados:
(Haga click en el botón de la aplicación que desee)
WB   IF  
Indique que divisas

 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
Neurophysin II Antibody (A-20) sc-27094 200 µg/ml $279
Neurophysin II (A-20) P sc-27094 P
(peptide)
 100 µg/0.5 ml $61
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano AVP 551 20p13 NM_000490 P01185
 192340
 

The nonapeptide hormones arginine vasopressin (AVP) and oxytocin are synthesized in the supraoptic and paraventricular nuclei of the hypothalamus together with their respective ‘carrier’ proteins, the neurophysins (1). Vasopressin and oxytocin are produced by separate populations of magnocellular neurons in both nuclei. Neurophysin I (NPI) and neurophysin II (NPII) function as carrier proteins for oxytocin and vasopressin, respectively (2,3). Oxytocin is a pituitary hormone which induces uterine contractions during childbirth and the ejection of milk from the mammary glands during nursing (4). Vasopressin is involved in the metabolism of water and electrolytes and has been identified as a vasoconstrictor (5). Both neurophysin genes exist as three exons, with each exon encoding a functional protein domain (4). Studies show that the identically conserved middle region (exon B) is involved in NP-NP homodimer formation as well as being the site for the glycine 17 to valine point mutation responsible for familial diabetes insipidus (6,7). The genes encoding neurophysin I and II map to human chromosome 20p13 (8).