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C12orf53 Anticuerpo(S-20): sc-242025

 |  Ficha Técnica

(Basado en el análisis de datos)
  • C12orf53 Antibody (S-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within a cytoplasmic domain of C12orf53 of human origin
  • recommended for detection of C12orf53 of human origin, C530028O21Rik of mouse origin and the corresponding rat homolog by WB, IF and ELISA; also reactive with additional species, including equine, bovine and porcine
  • blocking peptide, sc-242025 P
 

Ver tambiénC12orf53 Antibodies.

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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
C12orf53 Antibody (S-20) sc-242025 200 µg/ml $279
C12orf53 (S-20) P sc-242025 P
(peptide)
 100 µg/0.5 ml $61
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano C12orf53 196500 12p13.31 NM_153685 Q8IYJ0
 n/a
Ratón C530028O21Rik 319352 6 F2 NM_001145926, NM_001145927, NM_175696 Q6P1B3
 No Disponible
 

Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf53 gene product has been provisionally designated C12orf53 pending further characterization.