Date published: 2026-7-17

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Diethyl 2-phenylethyl phosphonate (CAS 54553-21-8)

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Application:
Diethyl 2-phenylethyl phosphonate is a Wadsworth-Emmons reagent
CAS Number:
54553-21-8
Molecular Weight:
242.25
Molecular Formula:
C6H5(CH2)2PO(OC2H5)2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Diethyl 2-phenylethyl phosphonate is a reactant for the preparation of 1,3-diketones, beta-keto esters, and beta-keto phosphonates via 1,2-addition of carbanionic nucleophiles to cyclic vinylogous acyl triflates, followed by ring-opening fragmentation, claisen condensation and carbon-carbon bond cleavage. It is used as a reagent in the synthesis of phospholipids, which are essential components of cell membranes. Diethyl 2-phenylethyl phosphonate can interact with enzymes and other proteins that contain nucleophilic groups, leading to the formation of covalent bonds. This property makes it useful in the study of enzyme kinetics and protein structure.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Diethyl 2-phenylethyl phosphonate, 10 g

sc-234644
10 g
$105.00