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8-iso Misoprostol (CAS 1256643-55-6)

Sinónimo:methyl7-[3-hydroxy-2-[(E)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl] heptanoate
Número CAS:1256643-55-6
Peso Molecular:382.5
Fórmula Molecular:C22H38O5
Refer to Certificate of Analysis for lot specific data (including water content).
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Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadirFavoritos
8-iso Misoprostol sc-223751 1 mg $89
8-iso Misoprostol sc-223751A 5 mg $403
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
Descripción
Misoprostol is a widely sold analog of prostaglandin E1 (PGE1) that has potent but relatively non-selective agonist activity with respect to the prostanoid EP receptor subgroup. Misoprostol has been used therapeutically for many years in humans for treatment of gastric ulcer disease under the Searle tradename Cytotec. 8-iso Misoprostol is one of several impurities which are possible in the production of bulk commercial preparations of misoprostol. It is also somewhat difficult to distinguish from other impurities such as 11β-misoprostol. The pharmacology and EP receptor binding affinity for 8-iso misoprostol has not been published.
Información Técnica
Formulación:A solution in ethanol
Estado Físico:Liquid
Almacenamiento:Store at -20° C
Seguridad e Información de Referencia
Transporte:UN 1170, Class 3, Packing group II
ID en PubChem:6030697
SMILES:CCCCC(C)(C/C=C/C1C(CC(=O)C1CCCCCCC(=O)OC)O)O
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.
References
1 Abramovitz, M., Adam, M., Boie, Y., et al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta 1483 285-293 (2000). 2 Collins, P.W. Misoprostol: Discovery, development, and clinical applications. Medicinal Research Reviews 10 149-172 (1990). 3 Iyer, R.R. Personal Communication. (2002).
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