Molecular structure of Cinalukast, CAS Number: 128312-51-6
Cinalukast (CAS 128312-51-6)
Alternate Names:
Ro 24-5913
Application:
Cinalukast is a selective antagonist of the CysLT1 Receptor (leukotriene D4 receptor)
CAS Number:
128312-51-6
Molecular Weight:
412.55
Molecular Formula:
C23H28N2O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Cinalukast is a potent, selective leukotriene D4 receptor antagonist.
Cinalukast (CAS 128312-51-6) References
- Ro 24-5913: a potent, specific, orally active LTD4 antagonist. | O'Donnell, M. 1991. Ann N Y Acad Sci. 629: 413-5. PMID: 1659286
- Complexation study of cinalukast and montelukast with cyclodextrines. | Durán Merás, I., et al. 2007. J Pharm Biomed Anal. 43: 1025-32. PMID: 17118608
- Participation of leukotriene C(4) in the regulation of suicidal erythrocyte death. | Foller, M., et al. 2009. J Physiol Pharmacol. 60: 135-43. PMID: 19826192
- A review on leukotrienes and their receptors with reference to asthma. | Singh, RK., et al. 2013. J Asthma. 50: 922-31. PMID: 23859232
- Computer-Assisted Selective Optimization of Side-Activities-from Cinalukast to a PPARα Modulator. | Pollinger, J., et al. 2019. ChemMedChem. 14: 1343-1348. PMID: 31141287
- MK-571, a Cysteinyl Leukotriene Receptor 1 Antagonist, Inhibits Hepatitis C Virus Replication. | Ruiz, I., et al. 2020. Antimicrob Agents Chemother. 64: PMID: 32179525
- In-silico discovery of inhibitors against human papillomavirus E1 protein. | Gunasinghe, J., et al. 2023. J Biomol Struct Dyn. 41: 5583-5596. PMID: 35751129
- Azologs of the fatty acid mimetic drug cinalukast enable light-induced PPARα activation. | Sai, M., et al. 2024. ChemMedChem. e202400327. PMID: 38895744
- Studies of the combination of Ro 24-5913, a peptidoleukotriene antagonist, and Ro 24-4736, a PAF antagonist, in guinea pig and rat models of lung inflammation. | Welton, AF., et al. 1994. Ann N Y Acad Sci. 744: 274-88. PMID: 7825850
- Prolonged protection against exercise-induced bronchoconstriction by the leukotriene D4-receptor antagonist cinalukast. | Adelroth, E., et al. 1997. J Allergy Clin Immunol. 99: 210-5. PMID: 9042047
Inhibitor of:
CysLT1 Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cinalukast, 10 mg | sc-203893 | 10 mg | $224.00 | |||
Cinalukast, 50 mg | sc-203893A | 50 mg | $902.00 |