Sodium sulfite (CAS 7757-83-7)

Sodium sulfite, the aqueous ion of sulfur dioxide, has been reported to contain pro-inflammatory properties in vitro and induce potent chemotactic factor IL-8 production. Mechanistic studies suggest that this compound could possibly act through signal transduction pathways NF-κ B, ERK, and p-38-dependent pathways. Sodium sulfite has also been shown to inhibit Candida albicans growth in RPMI1640 medium. Additional experiments note that this agent can induce cellular activation, resulting in degranulation in mast cells through a non-IgE-depent pathway.

SDS

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