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Página Principal » Químicos » Project-Id-Version: Report-Msgid-Bugs-To: POT-Creation-Date: 2013-05-13 21:34-0800 PO-Revision-Date: Last-Translator: M Language-Team: Language: es_US MIME-Version: 1.0 Content-Type: text/plain; charset=UTF-8 Content-Transfer-Encoding: 8bit X-Poedit-Basepath: /Library/WebServer/Documents/ X-Poedit-SourceCharset: UTF-8 X-Poedit-Bookmarks: -1,-1,719,-1,-1,-1,-1,-1,-1,-1 X-Generator: Poedit 1.5.3 X-Poedit-SearchPath-0: www.scbt.com Gramicidin A: sc-203061

Gramicidin A (CAS 11029-61-1)

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Solicitud:An effective antibiotic against Gram positive organisms
Número CAS:11029-61-1
Pureza:90%
Peso Molecular:1882.3
Fórmula Molecular:C99H140N20O17
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Gramicidin A sc-203061 1 mg $30
Gramicidin A sc-203061A 5 mg $79
Descripción
Gramicidin A is an antibiotic that is a naturally occurring ion channel-forming pentadecapeptide. Bacillus brevis produces Gramicidin and is an effective antibiotic against gram-positive organisms. Gramicidin can be used to study membrane channels because of its cation-selective, single-filing pore and has been used as a model to study ion channel proteins, and acylation of membrane proteins. The Gramicidin A channel has demonstrated to be permeable to small monovalent cations, protons, and water but impermeable to divalent cations and anions.
Información Técnica
Apariencia:White to off-white powder.
Estado Físico:Solid
Derivado de:Isolated from Bacillus brevis.
Secuencia:HCO-Val-Gly-Ala-D-Leu-Ala-D-Val-Val-D-Val-Trp-D-Leu-Trp-D-Leu-Trp-D-Leu-Trp-NHCH2CH2OH
Solubilidad:Soluble in DMSO, lower alcohols or acetic acid.
Almacenamiento:Store at -20° C
Seguridad e Información de Referencia
RTECS:MD8230000
ID en PubChem:16132269
Índice Merck:14: 4532
SMILES:OCCNC(=O)[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[ C@@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H]( NC(=O)[C@H](C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC=O)C(C )C)C(C)C)C(C)C)C(C)C)Cc1c[nH]c2ccccc12)Cc1c[nH]c2ccccc12)Cc1c[nH]c2ccccc12)C c1c[nH]c2ccccc12
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.
References
1. Dubos, R.J. and Hotchkiss, R.D. 1941. J. Exp. Med. 73: 629-640. PMID: 19871101
2. Stankovic, C.J., et al. 1990. Anal. Biochem. 184: 100-103. PMID: 1690956
3. Seoh, S.A. and Busath, D. 1993. Biophys. J. 64: 1017-1028. PMID: 7684267
4. Koeppe, R.E., et al. 1995. Biochemistry. 34: 9299-9306. PMID: 7542918
5. Prabhananda, B.S., et al. 1996. Biophys. J. 71: 3091-3097. PMID: 8968580
Gramicidin A (CAS 11029-61-1) Menciones del Producto
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