¡Bienvenido a Santa Cruz Biotechnology!
SCBT Home
Página Principal » Químicos » Antibiotics » Puromycin Aminonucleoside: sc-200112

Puromycin Aminonucleoside (CAS 58-60-6)

(Basado en popularidad)

Solicitud:The aminonucleoside portion of the antibiotic puromycin
Número CAS:58-60-6
Pureza:98%
Peso Molecular:294.3
Fórmula Molecular:C12H18N6O3
Indique que divisas

 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
Puromycin Aminonucleoside sc-200112 50 mg $194
Puromycin Aminonucleoside sc-200112A 250 mg $750
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
Descripción
Puromycin Aminonucleoside (3'-Amino-3'-deoxy-N6,N6-dimethyladenosine) is the aminonucleoside portion of the antibiotic puromycin. It is a puromycin analog which does not inhibit protein synthesis or induce apoptosis. Used in the study of focal and segmental glomerulosclerosis and in the induction of nephrosis in rats. The excretion of sodium and NOx metabolites in rats with puromycin aminonucleoside-induced nephrotic syndrome has been studied. Used to probe endothelial glycosaminoglycan synthesis in cultured glomerular endothelial cells and their relation to cell permeability.
Uso
• This product is not for selection and maintenance of cell lines expressing a transfected pac gene. For the selection of stably transfected cells following transfection with Santa Cruz Biotechnology shRNA or Lentiviral particles, we recommend the following: Puromycin dihydrochloride (sc-108071)
Información Técnica
Apariencia:White
Estado Físico:Solid
Solubilidad:Soluble in water (10 mg/ml)
Almacenamiento:Store at -20° C
Punto de Fusión:215-216 °C (lit.)
Punto de Ebullición:595.61 °C at 760 mmHg
Densidad:1.71 g/cm3
Índice de Refracción:n20D 1.78
Seguridad e Información de Referencia
Transporte:UN 3462, Class 6.1, Packing group III
WGK Alemania:3
RTECS:AU7337000
ID en PubChem:6020
Número MDL:MFCD00063462
Número EC:200-388-3
Registro Beilstein:93902
SMILES:[C@H]1([C@H](O[C@H]([C@@H]1O[H])N2CNC3=C2N=CN=C3N(C)C)CO[H])N([H])[H]
Para Uso Exclusivo en Investigación. No está diseñado para uso en diagnosis o terapia.
References
1. Gwinner, W., et al. 1997. J. Am. Soc. Nephrol. 8: 1722-1731. PMID: 9355075
2. Shirato, I., et al. 2000. J. Am. Soc. Nephrol. 11: 2381-2386. PMID: 11095662
3. Sörensson, J., et al. 2003. Am. J. Physiol. Renal Physiol. 284: F373-F380. PMID: 12388398
4. Ni, Z. and Vaziri, N.D. 2003. Biochim. Biophys. Acta. 1638: 129-137. PMID: 12853118
5. McDonough, A.A., et al. 2003. Curr. Opin. Nephrol. Hypertens. 12: 533-541. PMID: 12920402
6. Mattoo, T.K. and Kovacevic, L. 2003. Pediatr. Nephrol. 18: 872-877. PMID: 12836089
7. Fogo, A.B. 2003. Semin. Nephrol. 23: 161-171. PMID: 12704576
8. Bae, E.H., et al. 2009. Korean J. Physiol. Pharmacol. 13: 1-7. PMID: 19885019
SDS
Categorías de Productos Relacionados