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NPAS4 Anticuerpo(N-12): sc-168790

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(Basado en el análisis de datos)

  • NPAS4 Antibody (N-12) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of NPAS4 of human origin
  • recommended for detection of NPAS4 of mouse, rat and human origin by WB, IF and ELISA; non cross-reactive with other NPAS family members ; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-168790 P
 

Ver tambiénNPAS AntibodiesincluyebdoNPAS, NPAS1, NPAS2, NPAS3yNPAS4.

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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
NPAS4 Antibody (N-12) sc-168790 200 µg/ml $279
NPAS4 (N-12) P sc-168790 P
(peptide)
 100 µg/0.5 ml $61
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano NPAS4 266743 11q13.2 NM_178864 Q8IUM7
 608554
Ratón Npas4 225872 19 A NM_153553 Q8BGD7
 No Disponible
 

The Per-Arnt-Sim (PAS) domain is a 270 amino acid motif that mediates associations among various PAS family transcription factors. The PAS family contains neuronal specific transcription factors known as NPAS1, NPAS2, NPAS3 and NPAS4, which are involved in the development and maintenance of learning and memory pathways. NPAS1 regulates erythropoietin expression in developing brain. NPAS2, also designated PAS 4/MOP4, associates with MOP3 to activate transcription. NPAS3, which localizes to the nucleus and is ubiquitously expressed in the adult brain, may be involved in neurogenesis and has been implied to control regulatory pathways relevant to psychotic illness and schizophrenia. NPAS4 (neuronal PAS domain protein 4), also known as NXF, Le-PAS, PASD10 or bHLHe79, is a 802 amino acid nuclear protein that is exclusively expressed in the brain. NPAS4 acts as a transcriptional activator in the presence of Arnt 1, and activates the CME (CNS midline enhancer) element and expression of the Drebrin gene.