IKKγ Antibody (B-10): sc-166700

IKKγ Antibody (B-10) is a mouse monoclonal IgG1 kappa kappa light chain antibody targeting IKKγ, also known as NEMO (NF-κB Essential Modulator). Located in the cytoplasm, IKKγ/NEMO is a crucial component of the IKK complex that regulates the activation of the NF-κB transcription factor, which is essential for immune and inflammatory responses. The cytoplasmic localization of IKKγ enables effective response to proinflammatory signals, ensuring proper cellular regulation and function. Understanding and detecting IKKγ is crucial for research into inflammatory diseases, cancer, and immune disorders, making anti-IKKγ antibody (B-10) an essential resource for elucidating NF-κB signaling pathways and their role in disease progression. IKKγ monoclonal antibody (B-10) recognizes the epitope spanning amino acids 395-412 at the C-terminus of mouse IKKγ, providing high specificity and affinity for reliable detection. IKKγ (B-10) antibody is reactive with mouse, rat, and human IKKγ, and also cross-reacts with additional species including canine and porcine, making IKKγ (B-10) monoclonal antibody versatile for various research applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-IKKγ antibody (B-10) facilitates the study of the NF-κB signaling pathway, which is pivotal in processes like inflammation, immune response, and cell survival.

The preferred IKKγ antibody is IKKγ Antibody (B-3): sc-8032.