Date published: 2026-7-8

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TLE Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of TLE Antibodies for investigating Transducin-Like Enhancers of Split in various biological processes. TLE Antibodies are validated for multiple applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Transducin-Like Enhancers of Split function as transcriptional co-repressors involved in numerous cellular processes, including development, differentiation, and cell signaling. The role of Transducin-Like Enhancers of Split in modulating gene expression makes them significant targets in cancer research and neurodegenerative disease studies. Researchers can explore molecular mechanisms and signaling pathways through precise detection and analysis of Transducin-Like Enhancers of Split. Understanding the function and regulation of Transducin-Like Enhancers of Split can reveal new therapeutic targets and potential interventions. Investigating protein-protein interactions and expression patterns of Transducin-Like Enhancers of Split advances knowledge in developmental biology and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to make meaningful contributions to scientific understanding of cellular regulation and disease processes.

SEE ALSO...

TLE Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

TLE1 Antibody (F-4)

sc-137098mouse IgG1 κ200-350 (m)WB, IP, IF, ELISAm, r, h
1
(8)

TLE1 Antibody (C-7)

sc-137097mouse IgG1 κ200-350 (m)WB, IP, IF, ELISAm, r, h
2
(3)

TLE2 Antibody (D-10)

sc-374226mouse IgG1 κ230-420 (h)WB, IP, IF, ELISAm, r, h

new

(3)

TLE3 Antibody (D-10)

sc-514798mouse IgG1 κ200-400 (m)WB, IP, IF, IHC(P), ELISAm, r, h
2
(1)

TLE4 Antibody (E-10)

sc-365406mouse IgG1 κ273-473 (m)WB, IP, IF, IHC(P), ELISAm, r, h
30
(8)

TLE5 Antibody (C-7)

sc-515756mouse IgG2b κ127-197 (h)WB, IP, IF, ELISAm, r, h

new

(1)

TLE6 Antibody (D-4)

sc-515065mouse IgG1 λ58-77 (m)WB, IP, IF, ELISAm, r, h
1
(1)

TLE siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TLE1 siRNA (h)

sc-38558hGene SilencingN/A0
(0)

TLE1 shRNA Plasmid (h)

sc-38558-SHhGene SilencingPuromycin0
(0)

TLE1 shRNA (h) Lentiviral Particles

sc-38558-VhGene SilencingPuromycin0
(0)

TLE1 siRNA (m)

sc-38559mGene SilencingN/A0
(0)

TLE1 shRNA Plasmid (m)

sc-38559-SHmGene SilencingPuromycin0
(0)

TLE1 shRNA (m) Lentiviral Particles

sc-38559-VmGene SilencingPuromycin0
(0)

TLE2 siRNA (h)

sc-38560hGene SilencingN/A0
(0)

TLE2 shRNA Plasmid (h)

sc-38560-SHhGene SilencingPuromycin0
(0)

TLE2 shRNA (h) Lentiviral Particles

sc-38560-VhGene SilencingPuromycin0
(0)

TLE2 siRNA (m)

sc-38561mGene SilencingN/A0
(0)

TLE2 shRNA Plasmid (m)

sc-38561-SHmGene SilencingPuromycin0
(0)

TLE2 shRNA (m) Lentiviral Particles

sc-38561-VmGene SilencingPuromycin0
(0)

TLE3 siRNA (h)

sc-36683hGene SilencingN/A0
(0)

TLE3 shRNA Plasmid (h)

sc-36683-SHhGene SilencingPuromycin0
(0)

TLE3 shRNA (h) Lentiviral Particles

sc-36683-VhGene SilencingPuromycin0
(0)

TLE3 siRNA (m)

sc-36684mGene SilencingN/A
2
(0)

TLE3 shRNA Plasmid (m)

sc-36684-SHmGene SilencingPuromycin
2
(0)

TLE3 shRNA (m) Lentiviral Particles

sc-36684-VmGene SilencingPuromycin
2
(0)

TLE4 siRNA (h)

sc-38562hGene SilencingN/A0
(0)

TLE4 shRNA Plasmid (h)

sc-38562-SHhGene SilencingPuromycin0
(0)

TLE4 shRNA (h) Lentiviral Particles

sc-38562-VhGene SilencingPuromycin0
(0)

TLE4 siRNA (m)

sc-38563mGene SilencingN/A0
(0)

TLE4 shRNA Plasmid (m)

sc-38563-SHmGene SilencingPuromycin0
(0)

TLE4 shRNA (m) Lentiviral Particles

sc-38563-VmGene SilencingPuromycin0
(0)

TLE5 siRNA (h)

sc-63133hGene SilencingN/A0
(0)

TLE5 shRNA Plasmid (h)

sc-63133-SHhGene SilencingPuromycin0
(0)

TLE5 shRNA (h) Lentiviral Particles

sc-63133-VhGene SilencingPuromycin0
(0)

TLE5 siRNA (m)

sc-63134mGene SilencingN/A0
(0)

TLE5 shRNA Plasmid (m)

sc-63134-SHmGene SilencingPuromycin0
(0)

TLE5 shRNA (m) Lentiviral Particles

sc-63134-VmGene SilencingPuromycin0
(0)

TLE6 siRNA (h)

sc-97764hGene SilencingN/A0
(0)

TLE6 shRNA Plasmid (h)

sc-97764-SHhGene SilencingPuromycin0
(0)

TLE6 shRNA (h) Lentiviral Particles

sc-97764-VhGene SilencingPuromycin0
(0)

TLE CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TLE1 CRISPR/Cas9 KO Plasmid (h)

sc-400343Gene Knockouth0
(0)

TLE1 HDR Plasmid (h)

sc-400343-HDRHomology Directed Repairh0
(0)

TLE1 CRISPR/Cas9 KO Plasmid (m)

sc-423412Gene Knockoutm0
(0)

TLE2 CRISPR/Cas9 KO Plasmid (h)

sc-402718Gene Knockouth0
(0)

TLE2 HDR Plasmid (h)

sc-402718-HDRHomology Directed Repairh0
(0)

TLE2 CRISPR/Cas9 KO Plasmid (m)

sc-423413Gene Knockoutm0
(0)

TLE3 CRISPR/Cas9 KO Plasmid (h)

sc-400386Gene Knockouth0
(0)

TLE3 CRISPR/Cas9 KO Plasmid (m)

sc-423414Gene Knockoutm0
(0)

TLE4 CRISPR/Cas9 KO Plasmid (h)

sc-401215Gene Knockouth0
(0)

TLE4 HDR Plasmid (h)

sc-401215-HDRHomology Directed Repairh0
(0)

TLE4 CRISPR/Cas9 KO Plasmid (m)

sc-423415Gene Knockoutm0
(0)

TLE4 HDR Plasmid (m)

sc-423415-HDRHomology Directed Repairm0
(0)

TLE CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TLE1 CRISPR Activation Plasmid (h)

sc-400343-ACTGene Activationh0
(0)

TLE4 CRISPR Activation Plasmid (h)

sc-401215-ACTGene Activationh0
(0)