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p-TH Anticuerpo(Ser 19): sc-135713

 |  Ficha Técnica

(Basado en el análisis de datos)

  • p-TH Antibody (Ser 19) is a rabbit polyclonal IgG provided at 100µl
  • recommended for detection of Ser 19 phosphorylated TH of rat origin by WB, IP and IF
 

Ver tambiénTH Antibodies.

Información sobre pedidos
Productos Complementarios Recomendados:
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WB   IP   IF  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
p-TH Antibody (Ser 19) sc-135713 100 µl $279
 Lisado de células para control positivo de Western Blot (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
PC-12 Cell Lysate sc-2250 500 µg/200 µl $104


The enzyme tyrosine hydroxylase (TH), also designated tyrosine 3-monooxygenase (TY3H), catalyzes the conversion of tyrosine to L-DOPA. This is the rate limiting step in the biosynthesis of catecholamines such as dopamine, adrenalin and noradrenalin.Protein Kinase A (PKA) mediated phosphosphorylation at Serine 40 causes increased TH catalytic activity. Expressed mainly in the brain and adrenal glands, TH may play a role in the pathogenesis of Parkinson’s disease and the associated reduction in dopamine levels. The human tyrosine hydroxylase gene maps to 11p15. The phosphorylation of rat TH on Ser 19 by CaMKII leads to an increase in TH catalytic activity.

p-TH Antibody (Ser 19) Data
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p-TH (Ser 19): sc-135713. Western blot analysis of TH phosphorylation in purified non-phosphorylated rat recombinant TH fusion protein (A) and untreated PC-12 (B) and KCl-stimulated PC-12 (C) whole cell lysates.
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