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CTH Anticuerpo(H-167): sc-135203

 |  Ficha Técnica

(Basado en el análisis de datos)

  • CTH Antibody (H-167) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 61-227 mapping within an internal region of CTH of human origin
  • recommended for detection of CTH isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
 
Secuencia completa de la proteína para CTH con inmunógeno inidcado:
MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS

Ver tambiénCTH Antibodies.

También verchemical CTH Inhibitorsochemical CTH Substrates for functional analysis of cellular responses to CTH.


Información sobre pedidos
Productos Complementarios Recomendados:
(Haga click en el botón de la aplicación que desee)
WB   IP   IF   IHC(P)   siRNA  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadirFavoritos
CTH Antibody (H-167) sc-135203 200 µg/ml $279
 Plásmido CRISPR/Cas9 y Plásmido HDR (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadirFavoritos
CTH CRISPR/Cas9 KO Plasmid (h) sc-401134 20 µg $345
CTH HDR Plasmid (h) sc-401134-HDR 20 µg $385
CTH CRISPR/Cas9 KO Plasmid (m) sc-430767 20 µg $345
CTH HDR Plasmid (m) sc-430767-HDR 20 µg $385
 Silenciadores de Genes siRNA (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadirFavoritos
CTH siRNA (h) sc-78973 10 µM $258
CTH siRNA (m) sc-142618 10 µM $258
CTH siRNA (r) sc-270000 10 µM $258
CTH (h)-PR sc-78973-PR 10 µM, 20 µl $23
CTH (m)-PR sc-142618-PR 10 µM, 20 µl $23
 Plásmidos shRNA (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadirFavoritos
CTH shRNA Plasmid (h) sc-78973-SH 20 µg $520
CTH shRNA Plasmid (m) sc-142618-SH 20 µg $520
 shRNA partículas antivirales (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadirFavoritos
CTH shRNA (h) Lentiviral Particles sc-78973-V 200 µl $625
CTH shRNA (m) Lentiviral Particles sc-142618-V 200 µl $625


CTH (cystathionine ©-lyase), also known as CSE or ©-cystathionase, is a member of the trans-sulfuration enzyme family and participates in the trans-sulfuration pathway. CTH is a cytoplasmic enzyme produced in the cytosol and is responsible for catalyzing the pyridoxal phosphate-dependent ∫-disulfide elimination reaction resulting in ammonium, pyruvate and thiocysteine. The thiocysteine that is produced may then react with other thiols (or cysteine) and form hydrogen sulfide (H2S). Thus, CTH is the major H2S-producing enzyme in kidney, liver, vascular smooth muscle cells and enterocytes. The endogenous production of H2S plays a significant role in the regulation of cellular functions, including cell growth, hyperpolarization of cell membranes, modulation of neuronal excitability and relaxation of smooth muscle cells. Mutations in the gene encoding CTH can result in the autosomal recessive disease cystathioninuria; a disorder characterized by the unusual accumulation of plasma cystathionine causing increased urinary excretion.

CTH Antibody (H-167) Data
Haga click en la imágen para agrandarla
CTH (H-167): sc-135203. Western blot analysis of CTH expression in non-transfected: sc-117752 (A) and mouse CTH transfected: sc-119499 (B) 293T whole cell lysates.
CTH (H-167): sc-135203. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic staining of hepatocytes.
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