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p-PDGFR-β Anticuerpo(Tyr 1021)-R: sc-12909-R

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(Basado en el análisis de datos)

  • p-PDGFR-β (Tyr 1021)-R Antibody is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to a short amino acid sequence containing phosphorylated Tyr 1021 of PDGFR-β of human origin
  • recommended for detection of Tyr 1021 phosphorylated PDGFR-β of mouse, rat and human origin by WB, IP and IF; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-12909 P
  • See 14 citations for p-PDGFR-β Anticuerpo (Tyr 1021)-R
 

Ver tambiénPDGFR AntibodiesincluyebdoPDGFR, PDGFR-alpha, PDGFR-betayPDGFRL.

También verPDGFR-beta Inhibitors for functional analysis of cellular responses to PDGFR-beta.


Información sobre pedidosMenciones del ProductoInformación del gen
Productos Complementarios Recomendados:
(Haga click en el botón de la aplicación que desee)
WB   IP   IF   siRNA  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
p-PDGFR-β (Tyr 1021) P sc-12909 P
(peptide)
 100 µg/0.5 ml $61
p-PDGFR-β (Tyr 1021)-R Antibody sc-12909-R 200 µg/ml $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 Silenciadores de Genes siRNA (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
PDGFR-β siRNA (h) sc-29442 10 µM $258
PDGFR-β siRNA (m) sc-36200 10 µM $258
PDGFR-β (h)-PR sc-29442-PR 10 µM, 20 µl $23
PDGFR-β (m)-PR sc-36200-PR 10 µM, 20 µl $23
 Plásmidos shRNA (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
PDGFR-β shRNA Plasmid (h) sc-29442-SH 20 µg $520
PDGFR-β shRNA Plasmid (m) sc-36200-SH 20 µg $520
 shRNA partículas antivirales (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
PDGFR-β shRNA (h) Lentiviral Particles sc-29442-V 200 µl $625
PDGFR-β shRNA (m) Lentiviral Particles sc-36200-V 200 µl $625
 Lisado de células para control positivo de WB (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
CCD-1064Sk + PDGF Cell Lysate sc-2264 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
PDGFR-β (h2): 293T Lysate sc-159386 100 µg/200 µl $205
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano PDGFRB 5159 5q33.1 NM_002609 P09619
 173410
Ratón Pdgfrb 18596 18 E1 P05622
 No Disponible
 

Platelet Derived Growth Factor (PDGF) is a mitogen for mesenchyme- and glia-derived cells. PDGF consists of two chains, A and B, which dimerize to form functionally distinct isoforms, PDGF-AA, PDGF-AB, and PDGF-BB. These three isoforms bind with different affinities to two receptor types, a and b, which are endowed with protein tyrosine kinase domains and undergo either homo- or heterodimerization as a consequence of ligand binding. Ligand stimulation of PDGFR-b leads to autophosphorylation at Tyr-857, which is the major autophosphorylation site, and Tyr-751, which is the major in vitro phosphorylation site. Autophosphorylation of Tyr-751, which lies in the kinase insert region, is required for binding of phosphatidylinositol-3 kinase to the receptor. These auto-phosphorylation events largely contribute to signal transduction through the PDGF receptor.

p-PDGFR-β Antibody (Tyr 1021)-R Menciones del Producto
Vea como otros han usado anticuerpos %catalog_number% y/o anticuerpos conjugados p-PDGFR-β (Tyr 1021)-R.


14 menciones totales
Cargando las citaciones
 
p-PDGFR-β Antibody (Tyr 1021)-R Data
Haga click en la imágen para agrandarla
sc-12909
Western blot detection of PDGFR-β phosphorylation in CCD-1064Sk cells (A,C) and CCD-1064Sk cells + PDGF (B,D). Blots were probed with p-PDGFR-β (Tyr 857)-R: sc-12907-R (A,B) and p-PDGFR-β (Tyr 1021)-R: sc-12909-R (C,D).
sc-12909
p-PDGFR-β (Tyr 1021)-R: sc-12909-R. Western blot analysis of PDGFR-β phosphorylation in untreated (A) and lambda protein phosphatase treated (B) NIH/3T3 whole cell lysates.
sc-12909
Western blot analysis of PDGFR-β phosphorylation in untreated (A,D), PDGF treated (B,E) and PDGF and lambda protein phosphatase treated (C,F) NIH/3T3 whole cell lysates. Antibodies tested include p-PDGFR-β (Tyr 1021)-R: sc-12909-R (A,B,C) and PDGFR-β (11H4): sc-80991 (D,E,F).
sc-12909
p-PDGFR-β (Tyr 1021)-R: sc-12909-R. Western blot analysis of PDGFR-β phosphorylation in NIH/3T3 whole cell lysate.
sc-12909
p-PDGFR-β (Tyr 1021): sc-12909. Western blot analysis of PDGFR-β phosphorylation in non-transfected: sc-117752 (A) and human PDGFR-β transfected: sc-159386 (B) 293T whole cell lysates.
sc-12909
Western blot analysis of PDGFR-β phosphorylation in non-transfected: sc-117752 (A,D), untreated human PDGFR-β transfected: sc-159386 (B,E) and lambda protein phosphatase treated human PDGFR-β transfected: sc-159386 (C,F) 293T whole cell lysates. Antibodies tested include p-PDGFR-β (Tyr 1021): sc-12909-R (A,B,C) and PDGFR-β (11H4): sc-80991 (D,E,F).
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