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p-PKC δ Anticuerpo(Thr 507): sc-11770

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(Basado en el análisis de datos)

  • p-PKC δ Antibody (Thr 507) is a goat polyclonal IgG provided at 200 µg/ml; also available as rabbit IgG provided at 200 µg/ml, sc-11770-R
  • recommended for detection of PKC δ of mouse, rat and human origin phosphorylated at Thr 507 by WB, IP, IF and ELISA
  • blocking peptide, sc-11770 P
  • See 9 citations for p-PKC δ Anticuerpo (Thr 507)
 

Ver tambiénPKC AntibodiesincluyebdoPKC, PKC alpha, PKC beta, PKC delta, PKC epsilon, PKC eta, PKC gamma, PKC iota, PKC lambda, PKC mu, PKC nu, PKC theta, PKC zetayPkc1.

También verPKC delta InhibitorsoPKC delta Substrates for functional analysis of cellular responses to PKC delta.


Información sobre pedidosMenciones del ProductoInformación del gen
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WB   IP   IF  
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 Información sobre pedidos
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
p-PKC δ Antibody (Thr 507) sc-11770 200 µg/ml $279
p-PKC δ (Thr 507) P sc-11770 P
(peptide)
100 µg/0.5 ml $61
p-PKC δ Antibody (Thr 507)-R sc-11770-R 200 µg/ml $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 Lisado de células para control positivo de WB (Haga click en el nombre del producto para obtener más información)
Nombre del productoNúmero de catálogoUnidadPrecioCantidadAñadir 
HeLa + PMA Cell Lysate sc-2258 500 µg/200 µl $104
RAW 264.7 + LPS/PMA Cell Lysate sc-2212 500 µg/200 µl $104
RAW 264.7 Whole Cell Lysate sc-2211 500 µg/200 µl $104
 
Especies Nombre del Gen Gene ID Ubicación en el cromosoma Numero de Acceso de Isoforma (ARNm) Número de Acceso de la Proteína Número OMIM™:
Humano PRKCD 5580 3p21.1 NM_006254, NM_212539 Q05655
176977
Ratón Prkcd 18753 14 B P28867
No Disponible
 


Protein kinase C (PKC) family members influence a variety of cellular functions, including cell growth, cell differentiation, hormone secretion and membrane function. PKC isoforms are calcium and phospholipid-dependent serine/threonine protein kinases. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKC ∂ phosphorylation on Thr-507 mediates inhibition of Jak2 and Stat3 function. PKC ∂ phosphorylates and associates with Stat3 on Ser-727 following induction by IL-6 to negatively regulate the DNA binding and transcriptional activity of Stat3. The Tyr-525, 523 and 565 residues in the catalytic domain are crucial for activation of PKC ∂. The Tyr-52, 155 and 187 residues of PKC ∂ reside within a regulatory domain. The residue Ser-643 appears to be an autophosphorylation site.

p-PKC δ Antibody (Thr 507) Menciones del Producto
Vea como otros han usado anticuerpos %catalog_number% y/o anticuerpos conjugados p-PKC δ (Thr 507).


9 menciones totales
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p-PKC δ Antibody (Thr 507) Data
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Western blot detection of PKC δ phosphorylation using untreated (A,C) and PMA-treated (B,D) HeLa cells. Blots were probed with p-PKC δ (Thr 507)-R: sc-11770-R (A,B) and PKC δ (C-20)-G: sc-937-G (C,D).
p-PKC δ (Thr 507): sc-11770. Western blot analysis of PKC δ phosphorylation in RAW 264.7 (A) and RAW 264.7 + PMA (B) whole cell lysates.
p-PKC δ (Thr 507)-R: sc-11770-R. Western blot analysis of PKC δ expression in NIH/3T3 whole cell lysate.
p-PKC δ (Thr 507): sc-11770. Western blot analysis of PKC δ phosphorylation in PMA treated (A) and PMA and lambda protein phosphatase treated (B) RAW 264.7 whole cell lysates.
Western blot analysis of PKC δ phosphorylation in untreated (A, C) and lambda protein phosphatase treated (B, D) RAW 264.7 whole cell lysates. Antibodies tested include p-PKC δ (Thr 507): sc-11770 (A, B) and PKC δ (C-20): sc-937 (D, E).
Western blot analysis of PKC δ phosphorylation in untreated (A, C) and lambda protein phosphatase treated (B, D) HeLa whole cell lysates. Antibodies tested include p-PKC δ (Thr 507)-R: sc-11770-R (A, B) and PKC δ (C-20): sc-937 (C, D).
Western blot analysis of PKC δ phosphorylation in untreated (A, C) and lambda protein phosphatase treated (B, D) RAW 264.7 whole cell lysates. Antibodies tested include p-PKC δ (Thr 507)-R: sc-11770-R (A, B) and PKC δ (C-20): sc-937 (C, D).
Western blot analysis of PKC δ phosphorylation in untreated (A,C) and lambda protein phosphatase (sc-200312A) treated (B,D) RAW 264.7 whole cell lysates. Antibodies tested include p-PKC δ (Thr 507)-R: sc-11770-R (A,B) and PKC δ (C-20): sc-937 (C,D).
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