Date published: 2026-8-21

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DNA Ligase Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of DNA Ligase monoclonal antibodies for various research applications. DNA Ligase monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). DNA ligases play a crucial role in DNA replication and repair by catalyzing the formation of phosphodiester bonds between adjacent nucleotides, thereby sealing nicks in the DNA backbone. Their function is essential for maintaining genomic integrity and facilitating proper cellular responses to DNA damage. Given their importance in various cellular processes, DNA ligases are significant targets for research in cancer biology, genetic disorders, and molecular biology. DNA Ligase monoclonal antibodies enable precise detection and analysis of DNA ligase expression patterns across different cell types and tissues. Studying DNA ligase activity helps advance understanding of DNA repair mechanisms and cell cycle regulation. DNA Ligase monoclonal antibodies support cutting-edge research that contributes to breakthroughs in DNA repair pathways and genome maintenance. Santa Cruz Biotechnology monoclonal antibodies for DNA Ligase research continue to support scientists in advancing our understanding of fundamental cellular processes and disease mechanisms.

SEE ALSO...

DNA Ligase Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

DNA Ligase I Antibody (C-5)

sc-271678mouse IgG1 κ3-21 (h)WB, IP, IF, ELISAm, r, h
4
(6)

DNA Ligase I Antibody (1A9)

sc-47703mouse IgG1 κFL (bovine)WB, IP, ELISAm, r, h
4
(2)

DNA Ligase I Antibody (10H5)

sc-56087mouse IgG11-919 (h)WB, IPh
3
(3)

DNA Ligase I Antibody (A-5)

sc-390235mouse IgG2a κ751-919 (h)WB, IP, IF, ELISAm, r, h
1
(2)

DNA Ligase I Antibody (F-5)

sc-390217mouse IgG2b κ751-919 (h)WB, IP, IF, ELISAm, r, h

new

(1)

DNA Ligase III Antibody (E-7)

sc-390922mouse IgG2a κ181-480 (h)WB, IP, IF, ELISAh
4
(5)

DNA Ligase III Antibody (7)

sc-135883mouse IgG12-115 (h)WB, IPm, r, h and canine
10
(4)

DNA Ligase IV Antibody (D-8)

sc-271299mouse IgG2a κ545-844 (h)WB, IP, IF, ELISAm, r, h
28
(9)

DNA Ligase siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DNA Ligase I siRNA (h)

sc-35198hGene SilencingN/A0
(0)

DNA Ligase I shRNA Plasmid (h)

sc-35198-SHhGene SilencingPuromycin0
(0)

DNA Ligase I shRNA (h) Lentiviral Particles

sc-35198-VhGene SilencingPuromycin0
(0)

DNA Ligase I siRNA (m)

sc-35199mGene SilencingN/A0
(0)

DNA Ligase I shRNA Plasmid (m)

sc-35199-SHmGene SilencingPuromycin0
(0)

DNA Ligase I shRNA (m) Lentiviral Particles

sc-35199-VmGene SilencingPuromycin0
(0)

DNA Ligase III siRNA (h)

sc-72079hGene SilencingN/A0
(0)

DNA Ligase III shRNA Plasmid (h)

sc-72079-SHhGene SilencingPuromycin0
(0)

DNA Ligase III shRNA (h) Lentiviral Particles

sc-72079-VhGene SilencingPuromycin0
(0)

DNA Ligase III siRNA (m)

sc-72086mGene SilencingN/A0
(0)

DNA Ligase III shRNA Plasmid (m)

sc-72086-SHmGene SilencingPuromycin0
(0)

DNA Ligase III shRNA (m) Lentiviral Particles

sc-72086-VmGene SilencingPuromycin0
(0)

DNA Ligase IV siRNA (h)

sc-37394hGene SilencingN/A
1
(0)

DNA Ligase IV shRNA Plasmid (h)

sc-37394-SHhGene SilencingPuromycin
1
(0)

DNA Ligase IV shRNA (h) Lentiviral Particles

sc-37394-VhGene SilencingPuromycin
1
(0)

DNA Ligase IV siRNA (m)

sc-72113mGene SilencingN/A0
(0)

DNA Ligase IV shRNA Plasmid (m)

sc-72113-SHmGene SilencingPuromycin0
(0)

DNA Ligase IV shRNA (m) Lentiviral Particles

sc-72113-VmGene SilencingPuromycin0
(0)

DNA Ligase CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

DNA Ligase I CRISPR/Cas9 KO Plasmid (h)

sc-402830Gene Knockouth0
(0)

DNA Ligase I HDR Plasmid (h)

sc-402830-HDRHomology Directed Repairh0
(0)

DNA Ligase I CRISPR/Cas9 KO Plasmid (m)

sc-421434Gene Knockoutm0
(0)

DNA Ligase I HDR Plasmid (m)

sc-421434-HDRHomology Directed Repairm0
(0)

DNA Ligase III CRISPR/Cas9 KO Plasmid (h)

sc-402841Gene Knockouth0
(0)

DNA Ligase III HDR Plasmid (h)

sc-402841-HDRHomology Directed Repairh0
(0)

DNA Ligase III CRISPR/Cas9 KO Plasmid (m)

sc-421435Gene Knockoutm0
(0)

DNA Ligase III HDR Plasmid (m)

sc-421435-HDRHomology Directed Repairm0
(0)

DNA Ligase IV CRISPR/Cas9 KO Plasmid (h)

sc-401372Gene Knockouth0
(0)

DNA Ligase IV HDR Plasmid (h)

sc-401372-HDRHomology Directed Repairh0
(0)

DNA Ligase IV CRISPR/Cas9 KO Plasmid (m)

sc-435638Gene Knockoutm0
(0)

DNA Ligase IV HDR Plasmid (m)

sc-435638-HDRHomology Directed Repairm0
(0)

DNA Ligase CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

DNA Ligase I Double Nickase Plasmid (h)

sc-402830-NICGene Knockouth0
(0)

DNA Ligase I Double Nickase Plasmid (h2)

sc-402830-NIC-2Gene Knockouth0
(0)

DNA Ligase III Double Nickase Plasmid (h)

sc-402841-NICGene Knockouth0
(0)

DNA Ligase III Double Nickase Plasmid (h2)

sc-402841-NIC-2Gene Knockouth0
(0)

DNA Ligase IV Double Nickase Plasmid (h)

sc-401372-NICGene Knockouth0
(0)

DNA Ligase IV Double Nickase Plasmid (h2)

sc-401372-NIC-2Gene Knockouth0
(0)

DNA Ligase CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

DNA Ligase I CRISPR Activation Plasmid (h)

sc-402830-ACTGene Activationh0
(0)

DNA Ligase I Lentiviral Activation Particles (h)

sc-402830-LACGene Activationh0
(0)

DNA Ligase III CRISPR Activation Plasmid (h)

sc-402841-ACTGene Activationh0
(0)

DNA Ligase III CRISPR Activation Plasmid (h2)

sc-402841-ACT-2Gene Activationh0
(0)