PTER Anticuerpo(G-13): sc-107075

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PTER (phosphotriesterase related), also known as RPR-1, is a 349 amino acid protein that is highly expressed in kidney and, using zinc as a cofactor, is thought to play a role in maintaining kidney function. The gene encoding PTER maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie-Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.