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NOMBRE DEL PRODUCTO NÚMERO DE CATÁLOGODESCRIPCIÓNMENCIONESCLASIFICACIÓN
1-Norokadaonesc-287172Shown to exhibit inhibitory effects on Serine/Threonine Phosphatases and potential use as an okadaic acid negative control. NÚMERO DE CAS 131204-29-0

8-MA-cAMPsc-257017A selective cAMP-dependent protein kinase (PKA) activator and a site selective cyclic AMP analog with a similar affinity to site B of both protein kinase A type I and II. A priming analog which acts synergistically together with analogs showing site A preference. Together with e.g. 8-piperidino cAMP, selective stimulation of type I can be achieved NÚMERO DE CAS 33823-18-6

8-PIP-cAMPsc-257021A selective cAMP-dependent protein kinase (PKA) activator which is a site selective cyclic AMP analog with high selectivity for the site A of protein kinase A type I and site B of type II. Acts synergistically together with analog having opposite site-selectivity. NÚMERO DE CAS 31357-06-9

AD 198sc-252351A PKC-delta activator. Phospholipid scramblase 3 (PLS3) is an enzyme which plays a crucial role in mitochondrial morphology, functions, and apoptotic response. During apoptosis, activated protein kinase C-delta (PKC-delta) translocates to mitochondria and phosphorylates PLS3. Used to show that PLS3 is a critical downstream effector of PKC-delta in AD 198-induced apoptosis. NÚMERO DE CAS 98983-21-2

Akt1/2 kinase inhibitorsc-300173An Isozyme selective Akt1/2 kinase inhibitor.

CKI-7 dihydrochloridesc-252621A CK1 inhibitor which also inhibits SGK, S6K1 and MSK1. Inhibits SGK as potently as CK1. NÚMERO DE CAS 1177141-67-1

DCP-LAsc-255068DCP-LA is a selective PKCε activator. NÚMERO DE CAS 28399-31-7

Guanosine 3',5'-cyclic monophosphorothioate, Rp Isomer triethylammonium saltsc-252867cGMPS-dependent protein kinase Iå inhibitor. NÚMERO DE CAS 86562-09-6

KRIBB3sc-252935An inhibitior of PKC-dependent phosphorylation of Hsp27 through its direct binding to Hsp27. Has antimigratory and anti-invasive activities in MDA-MB-231 cells. KRIBB3 blocked phorbol 12-myristate 13-acetate-induced phosphorylation of Hsp27 and tumor cell migration. NÚMERO DE CAS 129414-88-6

Methyl Okadaatesc-295454Serine/Threonine protein phosphatase inhibitor NÚMERO DE CAS 78111-14-5

Okadaic Acid, Potassium Saltsc-202261An inhibitor of PP1, PP2A, PP2B, PP2C and endogenous phosphatase smooth muscle myosin. Additionally used to study tumor promotion, nitric oxide metabolism, apoptosis, cell cycling and calcium signaling. NÚMERO DE CAS 155751-72-7

Staurosporinesc-3510Staurosporine inhibits PKC and most other kinases, including tyrosine kinases; binds to ATP binding domain; inhibits topoisomerase II. NÚMERO DE CAS 62996-74-1

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SB 220025 trihydrochloridesc-253537A potent, specific inhibitor of human p38 mitogen-activated protein (MAP) kinase. NÚMERO DE CAS 197446-75-6

SB 431542 hydratesc-255604A potent and selective inhibitor of transforming growth factor-β superfamily type I activin receptor-like kinase (ALK) receptors. NÚMERO DE CAS 301836-41-9 (anhydrous)

SB-505124sc-362794SB-505124 is an inhibitor of activin receptor-like kinase (ALK-5). SB-505124 is demonstrated to suppress the action of transforming growth factor-B (TGF-B) both in vitro and in vivo. NÚMERO DE CAS 694433-59-5

SB-505124 hydrochloride hydratesc-253542Selective inhibitor of transforming growth factor-β type I receptor NÚMERO DE CAS 694433-59-5 (non-salt)

SIS3 hydrochloridesc-253565A specific inhibitor of Smad3 phosphorylation via inhibiting the effects of TGF-β1. Reestablishes myofibroblast differentiation of scleroderma fibroblasts via reducing expression of α-SMA. NÚMERO DE CAS 521984-48-5

SMER28sc-222320SMER28 is small molecule modulator of mammalian autophagy. NÚMERO DE CAS 307538-42-7

Sp-8-pCPT-cAMPSsc-253602A selective cAMP-dependent protein kinase (PKA) activator. Vial of 5 μmol. NÚMERO DE CAS 129693-13-6 (non-salt)