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NOMBRE DEL PRODUCTO NÚMERO DE CATÁLOGODESCRIPCIÓNMENCIONESCLASIFICACIÓN
2,3-DCPEsc-2001392,3-DCPE displays anticancer agent properties and inhibits Bcl-2 expression in certain cells. It also induces ERK activation, S-phase arrest and upregulates p21. NÚMERO DE CAS 418788-90-6

3
AG-1296sc-200631AG-1296 is a potent and selective inhibitor of PDGFR kinase both in vitro and in Swiss 3T3 cells. AG-1296 also inhibits Bek (FGF receptor) tyrosine kinase and c-kit. NÚMERO DE CAS 146535-11-7

3
Actinomycin Dsc-200906Actinomycin D is a metabolite isolated from Streptomyces parvulus that binds to the GpC steps of DNA. The compound acts as an RNA polymerase inhibitor and an antibiotic. NÚMERO DE CAS 50-76-0

1
8-Bromo-cAMPsc-2015648-Bromo-cAMP is a cell-permeable cAMP analog which activates cAMP-dependent protein kinase (PKA). NÚMERO DE CAS 76939-46-3

3
1-β-D-Arabinofuranosylcytosinesc-201628An antimetabolic agent which inhibits DNA polymerases α, δ, and ε, and RNA polymerases resulting in suppression of DNA synthesis and repair. NÚMERO DE CAS 147-94-4

2-Methoxyestradiolsc-2013712-Methoxyestradiol is an HIF-1 inhibitor of mediated transcriptional activation of target genes without affecting the transcription of HIF-1α itself and also disrupts microtubule function. NÚMERO DE CAS 362-07-2

3
A 419259 trihydrochloridesc-361094A 419259 trihydrochloride has been found to be an apoptosis inducing agent that inhibits Src family kinases (c-Src). NÚMERO DE CAS 364042-47-7

I-BET 151 Hydrochloridesc-391115I-BET 151 Hydrochloride is a BET bromodomain (BRD) inhibitor and blocks recruitment of BET to chromatin. NÚMERO DE CAS 1300031-49-5

Streptochlorinsc-391103Streptochlorin is an inhibitor of TNF-α-induced NF-κB activation and is a potent suppressor of angiogenesis. Possesses anticancer properties and induces apoptosis. NÚMERO DE CAS 120191-51-7

AG-490sc-202046AG-490 is a tyrosine kinase inhibitor of JAK2, EGFR, and Neu that belongs to the family of tyrphostins. NÚMERO DE CAS 134036-52-5

1
1,4-Benzoquinonesc-202873It is one of the major metabolites of benzene. It causes DNA damage and apoptosis through H2O2 generation in cells. NÚMERO DE CAS 106-51-4

AICARsc-200659AICAR strongly inhibits the transcription of PPARα, the coactivation of PPARα, and adipocyte differentiation. Can activate AMPK and mimic insulin activity. NÚMERO DE CAS 2627-69-2

9
13(S)-HPODEsc-20096413(S)-HPODE is a hydroperoxide shown to be a potent suppressor of platelets. NÚMERO DE CAS 33964-75-9

4
Apoptosis Activador 2sc-202956Apoptosis Activator 2 activates caspases in a cytochrome c-dependent manner and induces apoptosis in tumor cells. NÚMERO DE CAS 79183-19-0

BAY 11-7082sc-200615BAY 11-7082 is an irreversible, potent NF κ B inhibitor show to be a potential anti-inflammatory agent and apoptosis inducer. NÚMERO DE CAS 19542-67-7

10
12(S)-HETE sc-20094212(S)-HETE is an arachidonic acid metabolite synthesized in the 12-lipoxygenase pathway in platelets and macrophages. NÚMERO DE CAS 54397-83-0

1
3,5,4'-Trimethoxystilbenesc-201450An antiangiogenic agent and permethylated derivative of Resveratrol (sc-200808) that has been shown to inhibit endothelial cell proliferation, cause microtubule disassembly and tubulin depolymerization. NÚMERO DE CAS 22255-22-7

BX-912sc-364451BX-912 is a potent and selective PDK-1 inhibitor(IC50 = 12 nM). Competitively inhibits PDK-1 by binding to the ATP binding pocket. Slows cell growth and induces apoptosis in a variety of cancer cell lines. NÚMERO DE CAS 702674-56-4

Lovastatin sc-200850Lovastatin inhibits HMGCR (3-hydroxy-3-methylglutaryl coenzyme A reductase), blocking the enzyme-catalyzed transformation of 3-hydroxy-3-methylglutaryl CoA into mevalonate. NÚMERO DE CAS 75330-75-5

3
KN-93sc-202199KN-93 is an effective inhibitor of CaMKII phosphorylating activity. It has been shown to induce cell cycle arrest in HeLa and NIH 3T3 cell fibroblasts. NÚMERO DE CAS 139298-40-1

6
R406sc-364595R406 is an inhibitor to IgE and IgG-mediated to Fc receptor signaling activation, capable of producing apoptosis in certain cancer cell lines. Inhibitor of Syk and Flt-3. NÚMERO DE CAS 841290-81-1

Desipramine HClsc-200158Desipramine HCl is aselective inhibitor of noradrenaline transporters SLC6A2 (NET), ST (SERT; serotonin transporter), and DAT (dopamine transporter). NÚMERO DE CAS 58-28-6

2-Amino-N-quinolin-8-yl-benzenesulfonamidesc-213750An apoptosis inducer that inhibits cell cycle at G2 phase. NÚMERO DE CAS 16082-64-7

2-Chloro-2′-deoxyadenosinesc-202399A deoxyadenosine analog that induces apoptosis in chronic lymphocytic leukemia (CLL) cells. NÚMERO DE CAS 4291-63-8

Caylin-1sc-223878Caylin-1 is a nutlin-3 analog that activates p53 and subsequently induces apoptosis by disrupting MDM2-p53 interaction.

Ceruleninsc-200827Cerulenin is an antibiotic and antifungal agent that potently and specifically inhibits Fatty Acid Synthase (FAS), and has been shown to induce apoptosis in a caspase dependent manner. NÚMERO DE CAS 17397-89-6

Mevastatin (Compactin)sc-200853Mevastatin (Compactin) inhibits HMGCR (HMG-CoA reductase) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation. NÚMERO DE CAS 73573-88-3

9
4-Hydroxyphenylretinamidesc-2009004-Hydroxyphenylretinamide is a synthetic retinoid analog of all trans retinoic acid, which displays antiproliferative effects on cultured human breast cancer cells. NÚMERO DE CAS 65646-68-6

Cyclopaminesc-200929Cyclopamine is a natural product which inhibits the Smo protein of the hedgehog (Hh) signaling pathway, leading to cyclopia. NÚMERO DE CAS 4449-51-8

1
TBBsc-202830TBB is a cell-permeable benzotriazolo compound that acts as a highly selective PK and NS3 viral helicase inhibitor. TBB is also a competitive inhibitor of CK2α. NÚMERO DE CAS 17374-26-4

6
Betulinic Acidsc-200132Betulinic Acid is a cytotoxic agent that upregulates apoptotic proteins and affects mitochondrial membrane permeability. Also acts as a potent inhibitor of Hh/Gli signaling pathway. NÚMERO DE CAS 472-15-1

HLI 373sc-358833HLI 373 is an inhibitor of Hdm2 ubiquitin ligase (E3) which blocks Hdm2-mediated ubiquitylation, proteasomal degradation of p53 and activates p53-dependent transcription. NÚMERO DE CAS 502137-98-6

Imiquimodsc-200385Imiquimod is a TLR7 (toll-like receptor 7) activator. Inhibits angiogenesis, induces apoptosis and modifies the immune response. Suggested to activate caspase-3 and NFκB. NÚMERO DE CAS 99011-02-6

Mevastatin Sodiumsc-205752Mevastatin Sodium is the active carboxylate form of mevastatin (sc-200853) and an HMGCR (HMG-CoA reductase) inhibitor. Mevastatin Sodium is active in whole cells as well as in cell free assays.

PDK1/Akt/Flt Dual Pathway Inhibidorsc-222144PDK1/Akt/FLt dual pathway inhibitor is a potent inhibitor of PDK1, inducing apoptosis in inhibited cells. NÚMERO DE CAS 331253-86-2

Caylin-2sc-223879Caylin-2 disrupts the MDM2-p53 complex by inhibiting MDM2. This promotes apoptosis by increasing the concentration of free p53 in the cytoplasm.

ABT-888sc-202901ABT-888 has been shown to be a potent PARP (poly(ADP-ribose) polymerase) inhibitor which can result in apoptosis and suppression of cell growth. NÚMERO DE CAS 912445-05-7

4
5-[(1Z)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxy-phenolsc-290709Resveratrol is a natural polyphenolic antioxidant that has anti-cancer properties. This chemical is an analog of resveratrol which is a potent inducer of apoptosis in promyelocytic leukemia HL-60 cells (IC50 = 40 nM versus 50 μM for resveratrol). In addition, it induces apoptosis (IC50 = 30 nM) in HL60R, a cell line derived from HL-60 that expresses a multidrug-resistance phenotype (resistant to daunorubicin, etoposide, and citarabine). NÚMERO DE CAS 586410-08-4

1,5-Isoquinolinediolsc-2001271,5-Isoquinolinediol is an inhibitor of PARP-1, NOS2, and PARS. Presents cellular protective and neuroprotective properties. NÚMERO DE CAS 5154-02-9

2
Borrelidinsc-200379Borrelidin is an anti-angiogenic and anti-microbial compound that disrupts capillary tube formation by activating caspase-3 and caspase-8. It also inhibits ThrRS and HUVEC proliferation. NÚMERO DE CAS 7184-60-3

ICRF-193sc-200889ICRF-193 is a bisdioxopiperazine that is a catalytic noncleavable complex-forming inhibitor of DNA Topo II (topoisomerase II) that induces erythroid differentiation and apoptosis. NÚMERO DE CAS 21416-68-2

5′-Deoxy-5′-methylthioadenosinesc-202427A naturally-occurring co-product of polyamine biosynthesis that acts as a substrate of methylthioadenosine phosphorylase. NÚMERO DE CAS 2457-80-9

Quercetin Dihydratesc-203225Quercetin Dihydrate inhibits PLA2, PI 3-kinase, PI 4-kinase and PI-4-phosphate 5-kinase, and reduces IP3 levels, blocking oncogenic signaling. NÚMERO DE CAS 6151-25-3

Piceatannolsc-200610Piceatannol is a catechol-type polyphenol that preferentially inhibits Syk in comparison to Lyn. Also inhibits NF-κB activation and cyclooxygenase-2 expression. NÚMERO DE CAS 10083-24-6

1
Gliotoxinsc-201299Gliotoxin is a toxic epipolythiodioxopiperazine metabolite shown to be an immunosuppressive mycotoxin. Displays a capacity to induce apoptosis and inhibit NF-κB activation. NÚMERO DE CAS 67-99-2

PHA 767491 hydrochloridesc-204187PHA 767491 is a potent, ATP-competitive inhibitor of cdc7 (IC50: 10 nM) and cdk9 (IC50: 34 nM), and inhibits cell proliferation in multiple human cell lines. NÚMERO DE CAS 845714-00-3

7BIOsc-2211187BIO is a 3′ substituted kinase inhibitory bis-indole, which functions as a caspase independent nonapoptotic cell death inducer. NÚMERO DE CAS 916440-85-2

A23187sc-3591Highly selective calcium ionophore. Tool useful for increasing intracellular Ca2+ concentrations. Shown to induce cell activation, differentiation or proliferation. NÚMERO DE CAS 52665-69-7

10
3-O-Acetyl-β-boswellic acidsc-2028853-O-Acetyl-β-boswellic acid is a potent non-redox, non-competitive 5-LO (5-lipoxygenase) and Topo I (topoisomerase I) and Topo II (topoisomerase II) inhibitor. NÚMERO DE CAS 5968-70-7

CIL-102sc-214722CIL-102 is a semisynthetic alkaloid derivative, which inhibits cell growth in a wide variety of cancer cell lines in a dose dependent manner. NÚMERO DE CAS 479077-76-4

Amonafide-d6sc-217636Amonafide-d6 is a labeled Amonafide (sc-207283). A DNA intercalator and Topo II (topoisomerase II) inhibitor. Amonafide-d6 is also classified as an antitumor agent. NÚMERO DE CAS 69408-81-7 (unlabeled)

BADGEsc-202487BADGE is an inhibitor of the peroxisome proliferator-activated receptor (PPAR)-γ and adipocyte differentiation, and has been shown to induce apoptosis in tumor cells. NÚMERO DE CAS 1675-54-3

1
Simvastatinsc-200829Simvastatin is an HMGCR (HMG-CoA reductase) inhibitor with anti-proliferative properties. NÚMERO DE CAS 79902-63-9

3
1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphocholinesc-2028631-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphocholine is an ether lipid analogue that induces selective apoptosis in tumor cells without affecting normal cells. It has the ability to activate intracellular Fas/CD95 and inhibit activation of p70S6K. NÚMERO DE CAS 77286-66-9

Acyclovirsc-202906Acyclovir is an antiviral compound that can be used to induce apoptosis in cells transfected with HSV-TK, alter the cell cycle, and in gene therapy studies. NÚMERO DE CAS 59277-89-3

1
MG-132 [Z-Leu-Leu-Leu-CHO]sc-201270MG-132 [Z-Leu-Leu-Leu-CHO] is a potent, reversible and selective proteasome inhibitor. It has also been shown to inhibit the activity of NF κB and calpain. NÚMERO DE CAS 133407-82-6

2
DAPTsc-201315DAPT is a potent and specific inhibitor of the γ-secretase complex which is composed of four proteins: presenilin, nicastrin, APH-1 and PEN-2. It blocks the proteolytic processing of NRADD. NÚMERO DE CAS 208255-80-5

9
Pyrrolidinedithiocarbamic acid ammonium saltsc-203224Pyrrolidinedithiocarbamic acid ammonium salt is an NF kappa B inhibitor which suppresses NOS synthase mRNA. Also displays antioxidant and metal-ion chelating characteristics. NÚMERO DE CAS 5108-96-3

Lactacystinsc-3575Lactacystin is a potent and selective irreversible proteasome inhibitor and cathepsin A inhibitor. NÚMERO DE CAS 133343-34-7

11
Baicaleinsc-200494Baicalein has been shown to inhibit platelet 5-LO (5-lipoxygenase) (IC50=9.5 mM) and 12-LO (12-lipoxygenases) (IC50=0.12 mM) and reverse transcriptase. NÚMERO DE CAS 491-67-8

Cisplatinsc-200896Cisplatin is a potent platinum-based antineoplastic agents that is believed to form inter- and intrastrand DNA adducts. It has also been shown to induce apoptosis through caspase-3 activation and XIAP expression. NÚMERO DE CAS 15663-27-1

12
15(S)-HETE sc-20094415(S)-HETE is an arachidonic acid metabolite with immunosuppressive, stimulation of endothelial cellmigration and neovascularization and anti tumor activity. NÚMERO DE CAS 54845-95-3

Simvastatin, Sodium Saltsc-222312Simvastatin, Sodium Salt is the carboxylate form of Simvastatin (sc-200829), a lipophilic HMGCR (3-hydroxy-3-methylglutaryl coenzyme A reductase) inhibitor. NÚMERO DE CAS 12009-77-6

5
Adapalenesc-203803Adapalene is a retinoic acid analog that is a RARβ and RARγ agonist. Adapalene addtionally inhibits proliferation and induces apoptosis in colorectal cancer cells. NÚMERO DE CAS 106685-40-9

MIRA-1sc-204087MIRA-1 restores wild-type conformation, function and DNA binding activity to mutant p53. Induces p53 transcriptional transactivation of p21, MDM2 and PUMA. NÚMERO DE CAS 72835-26-8

PKC-412sc-200691PKC-412 has been reported to be an antiproliferatiive agent which inhibits protein kinase C. Additionally PKC-412 has been shown to increase endothelial nitric oxide (NO) synthase expression and NO production. NÚMERO DE CAS 120685-11-2

β-Lapachonesc-200875β-Lapachone, a novel topoisomerase I (Topo I) inhibitor, does not stabilize the cleavable complex indicating a novel mode of action, unlike Camptothecin (sc-200871). NÚMERO DE CAS 4707-32-8

5
Alendronate, Sodium Saltsc-202049A nitrogen-containing bisphosphate that acts as a robust inhibitor of bone resorption and induces apoptosis, and is a selective inhibitor of farnesyl diphosphate synthase. NÚMERO DE CAS 121268-17-5

2
Fibronectin Inhibidorsc-202156Fibronectin Inhibitor is a tetrapeptide which supports fibroblast attachment and inhibits fibronectin binding to platelets. NÚMERO DE CAS 91037-65-9

1
AM 80sc-203816AM 80 is a retinoic acid receptor α (RARα) agonist that also exhbits antiproliferatve effects against a wide variety of tumor cell lines. NÚMERO DE CAS 94497-51-5

Ozagrelsc-200760Ozagrel, an antithrombic drug, is a potent and selective thromboxane A2 (TXA2R) inhibitor and apoptosis inducer. NÚMERO DE CAS 82571-53-7

4
Antimycin Asc-202467Antimycin A is an antibiotic that induces apoptosis, inhibits the mitochondrial electron transport chain from cytochrome b to cytochrome C1, and generates ROS. NÚMERO DE CAS 1397-94-0

Brefeldin A (BFA)sc-200861Brefeldin A (BFA) blocks the GTP-dependent interaction of ARF with the Golgi membrane and inhibits secretion from the Golgi apparatus. It can induce apoptosis by activating caspase-3 and inhibit cell growth by targeting the cell cycle. NÚMERO DE CAS 20350-15-6

1
MS-1020sc-364120MS-1020 is a selective JAK3 inhibitor. MS-1020 blocks STAT signalMS-1020 is a selective JAK3 inhibitor. MS-1020 blocks STAT signaling and induces apoptosis via down-regulation of anti-apoptotic gene expression.ing and induces apoptosis via down-regulation of anti-apoptotic gene expression.

Fumonisin B1sc-201395Fumonisin B1 is a fungal metabolite that inhibits serine/threonine phosphatases. It also inhibits LASS (ceramide synthase), induces apoptosis. NÚMERO DE CAS 116355-83-0

1
Topotecansc-338718Topotecan is a Topo I (topoisomerase I )inhibitor, and semisynthetic derivative of Camptothecin, shown to stabilize topoisomerase I/DNA cleavable complexes. NÚMERO DE CAS 123948-87-8

API-1sc-361106 API-1 is a PKB inhibitor. The compound acts by halting Akt membrane translocation through binding the pleckstrin homology domain of Akt. API-1 also inhibits EGF-induced kinase activity of Akt1, AKT2 and AKT3. Activity results in cell growth arrest and apoptosis in human cancer cells with constitutively active Akt. Both in vivo and in vitro antitumor activity has been observed along with cell arrest and apoptosis in cancer cells with constitutive Akt activity. NÚMERO DE CAS 36707-00-3

Chelerythrine Chloridesc-3547Chelerythrine chloride Is an isoquinoline alkaloid that has It has been reported to be a potent and selective inhibitor of PKC (protein kinase C) as well as inducing apoptosis and preventing platelet aggregation. NÚMERO DE CAS 3895-92-9

8
Apoptolidinsc-202062A selective polyketide, apoptosis inducer produced by Nocardiopsis mainly inducing cell death in E1A-transformed cells and inhibiting the enzymatic activity of mitochondrial F0F1-ATPase. NÚMERO DE CAS 194874-06-1

1
p53 Activador III, RITAsc-202753p53 Activator III, RITA, also referred to as NSC 652287, is a trycyclic thiophene derivative that binds to MDM2 and activates p53, inducing apoptosis. NÚMERO DE CAS 213261-59-7

3
Ursolic Acidsc-200383Ursolic Acid has been reported to be an anti-angiogenic and anti-proliferative compound. Also has been shown to induce cell cycle arrest and apoptosis. NÚMERO DE CAS 77-52-1

Garcinolsc-200891Garcinol is a potent inhibitor of p300 and PCAF histone acetyltransferases. It promotes apoptosis through caspase-3 activation and predominantly down-regulates global gene expression in HeLa cells. NÚMERO DE CAS 78824-30-3

Chromomycin A3sc-200907Chromomycin A3 is a G-C specific DNA ligand which inhibits transcription. Reported to be a DNA stain as well as an antibiotic that prevents neuronal apoptosis induced by oxidative stress or DNA damage. NÚMERO DE CAS 7059-24-7

Apoptosis Activador VII, Apoptozolesc-221257Apoptosis Activator VII, Apoptozole is a cell-permeable imidazole compound that directly binds anti-apoptotic chaperone Hsc70 and its inducible homologue Hsp70.

C2 Phytoceramidesc-223853C2 Phytoceramide has been shown to inhibit yeast growth, and to act as a ceramide-activated protein phosphatase (CAPP) activator. NÚMERO DE CAS 475995-69-8

Adenosine 3′,5′-cyclic monophosphate sodium salt monohydratesc-291840Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate is a PKA activator. NÚMERO DE CAS 37839-81-9

Ara-G hydratesc-214548Ara-G hydrate (9-β-D-Arabinofuranosyl guanine) is an inducer of apoptosis, inhibitor of DNA synthesis, an antimetabolite, and antineoplastic. NÚMERO DE CAS 38819-10-2 (anhydrous)

Tyrphostin 9 (RG-50872, Malonaben, SF 6847)­sc-200568Tyrphostin 9 (RG-50872, Malonaben, SF 6847) is a PDGFR inhibitor and a calcium channel protein inhibitor. NÚMERO DE CAS 10537-47-0

C8 Ceramine, D-erythrosc-223854C8 Ceramine, D-erythro is an analog of ceramide in which the amide is substituted with an amine. This substitution renders it inert to ceramidases. NÚMERO DE CAS 170926-06-4

Ac-VEID-pNA, Colorimetric Substratesc-311281Ac-VEID-pNA, Colorimetric Substrate is a colorimetric substrate for caspase-6 and related cysteine proteases. The sequence is based on the lamin A site of cleavage. NÚMERO DE CAS 189684-54-6

PRIMA-1METsc-361295PRIMA-1MET is a methylated derivative of PRIMA-1 shown to restore mutant p53 activity and inhibit tumor cell proliferation. NÚMERO DE CAS 5291-32-7

Atractyloside Dipotassium Saltsc-363293Atractyloside is a natural compound that functions as a specific inhibitor of the adenine nucleotide translocase (ANT), which is a mitochondrial ADP/ATP carrier. Additionally, Atractyloside is a proapoptotic ligand of ANT that induces pore formation by ANT, and results in permeabilization of the mitochondria membrane. Rat heart studies indicate that Atractyloside inhibits chloride channels from the mitochondrial membrane. We supply the Atractyloside, Dipotassium Salt form. NÚMERO DE CAS 102130-43-8

Auraptenesc-202477Auraptene is a compound with anti-inflammatory, chemopreventive, apoptotic, cancer cell line suppression, PPAR agonist and ACAT inhibitory properties. NÚMERO DE CAS 495-02-3

Dibutyryl-cAMPsc-201567Dibutyryl-cAMP is an analog of cyclic AMP that stimulates PKA (cAMP-dependent protein kinase) and the activity of the Na+, K+-pump. NÚMERO DE CAS 16980-89-5

3
PMAsc-3576Highly potent, reversible PKC activator in vitro and in vivo. Tumor promoting compound that induces apoptosis in HL-60 promyelocytic leukemia cells. NÚMERO DE CAS 16561-29-8

8
Esculetinsc-200486Esculetin is a phenolic compound that acts as an inhibitor of 5-LO (5-lipoxygenase) and 12-LO (12-lipoxygenase). NÚMERO DE CAS 305-01-1

DuP-697sc-200680DuP-697, an anti-inflammatory agent, is an inhibitor of Cox-1 and Cox-2 with 50 fold more selectivity for Cox-2 than for Cox-1. It also suppresses cell growth and induces apoptosis by cell-cycle arrest and caspase-8 activation. NÚMERO DE CAS 88149-94-4

Suberoyl bis-hydroxamic Acidsc-200887Suberoyl bis-hydroxamic Acid, an HDAC (histone deacetylase) inhibitor, inhibits HDAC1 (ID50 = 0.25 μM) and HDAC3 (ID50 = 0.3 μM). NÚMERO DE CAS 38937-66-5

Baccatin IIIsc-204637Baccatin III is the precursor to paclitaxel/ taxol. Antileukaemic and antitumor agent isolated from the bark of the Pacific yew tree (Taxus breviofolia). Baccatin III binds to tubules when they are assembled in the cell and stabilizes the polymerized form of tubules so that they remain assembled even under conditions in which microtubules dissociate into tubulin subunits. Baccatin III is also an inducer of apoptosis and shows antitumor properties in vitro NÚMERO DE CAS 27548-93-2

K-252asc-200517K-252a is an inhibitor of PKA, PKC, Ser/Thr kinase, CaMKII, MYLK, Met, Cdc2, Cdc25, cGKI, PHK Trk A and PKN. NÚMERO DE CAS 99533-80-9

2
Benzalkonium Bromidesc-205600This compound functions as an ulcerative agent and preservative in most ophthalmic topical solutions. On epithelial conjunctival cells in vitro, cells die by necrosis at high concetrations and by apoptosis at low concentration. NÚMERO DE CAS 91080-29-4

Doxorubicin • HCl (Adriamycin)sc-200923Doxorubicin is a DNA intercalator and broad-spectrum antitumor agent. Shown to downregulate expression of the oncogenes c-Myc and c-Jun and inhibit Topo II (Topoisomerase II). NÚMERO DE CAS 25316-40-9

2
Berberine hemisulfatesc-202496Berberine Hemisulfate is a compound that exhibits anti-inflammatory, anti-diabetic, pro-cardiovascular, cholesterol lowering, anti-tumor and anti- depressant activity. NÚMERO DE CAS 633-66-9

Vinblastine Sulfatesc-201447Vinblastine Sulfate is an alkaloid with anti-neoplastic, anti-mitotic, immunosuppressive and apoptotic activity. It triggers Raf-1 activation, phosphorylation of Bcl-2 family proteins, and induces p53 expression. NÚMERO DE CAS 143-67-9

3
3,3'-Diindolylmethanesc-2046243,3′-Diindolylmethane is an anticancer and antineoplastic agent that is also an activator of cytochrome P450 and checkpoint kinase 2 (Chk2). NÚMERO DE CAS 1968-05-4

Bestatin Methyl Estersc-221350Bestatin methyl ester is a cell-permeable derivative of Bestatin which displays slightly stronger inhibition of neutral aminopeptidase than Bestatin, but has much weaker activity against basic aminopeptidase. NÚMERO DE CAS 65322-89-6

1
Astaxanthinsc-391006Astaxanthin is a powerful carotenoid antioxidant with cell-protective, anti-inflammatory, and anti-neoplastic properties. NÚMERO DE CAS 472-61-7

Bestatin hydrochloridesc-200564Bestatin hydrochloride is an inhibitor of aminopeptidases, LAP3, and leukotriene A4 hydrolase (LTA4). NÚMERO DE CAS 65391-42-6

Betamethasonesc-204647Betamethasone is a glucocorticoid that induces gene expression and apoptosis. NÚMERO DE CAS 378-44-9

Miltefosinesc-203135Mitefosine is a PI 3-kinase and Akt inhibitor that also blocks anti-IgE induced histamine release from skin mast cells. It has been shown to also reduce cytokines IL-1β, IL-4, and IL-6 in certain skin tissue cells. NÚMERO DE CAS 58066-85-6

1
BH3I-1sc-221352This is a cell permeable BH3 mimetic that binds to Bcl-XL. NÚMERO DE CAS 300817-68-9

Prodigiosinsc-202298Prodigiosin is a water insoluble, potent proapoptotic compound that belongs to a family of Prodigions isolated from gram-negative bacteria. It is also described as a red-pigmented antibiotic produced by Serratia marcescens strains. NÚMERO DE CAS 82-89-3

1
Ingenol 3,20-dibenzoatesc-202663Activates PKC. Induces apoptosis. Anticancer agent. Has potent antileukemic activity in the P388 mouse assay. Shows unusually high mouse ear inflammatory activity. NÚMERO DE CAS 59086-90-7

Pseudolaric acid Bsc-203221Pseudolaric acid B activates PPARα and the PLC signalling pathway. It also binds Tubulin, inhibits angiogenesis, reduces HIF-1α protein levels, induces apoptosis, and is an antifungal. NÚMERO DE CAS 82508-31-4

BH3I-1"sc-221354This is a cell permeable BH3 mimetic that binds to Bcl-XL.

Melittinsc-200868Melittin causes apoptosis via induction of reactive oxygen species production in cells. Melittin inhibits activator protein-1 as well as NF-κB, and activates PLA2. NÚMERO DE CAS 37231-28-0

Erlotinib Hydrochloridesc-202154Erlotinib Hydrochloride is an inhibitor of human epidermal growth factor receptor (HER-1/EGFR) tyrosine kinase, blocking EGFR signaling. NÚMERO DE CAS 183319-69-9

2
BH3I-2'sc-221355BH3I-2' is a cell-permeable BH3 mimetic that induces apoptosis by specifically preventing BH3 domain-mediated interaction between pro-apoptotic and anti-apoptotic members of the Bcl-2 family. NÚMERO DE CAS 315195-18-7

PLAPsc-200867The phospolipase A2 activating protein (PLAP) is a 21-residue fragment that spans the PLAP-melittin homology sequence and is a member of the β-transducin (Gβ) superfamily. NÚMERO DE CAS 137314-60-4

(±)-Naringeninsc-203155(±)-Naringenin inhibits the activity of PI 3-kinase. It also demonstrates anti-inflammatory and antitumor properties. NÚMERO DE CAS 67604-48-2

Bleomycin Sulfatesc-200134Bleomycin sulfate is a complex natural product antibiotic, approximates metals and dioxygen to produce a species capable of oxidatively damaging DNA and RNA. NÚMERO DE CAS 9041-93-4

7
Proscillaridin Asc-202775Proscillaridin A is a cardiac glycoside which functions as a specific Na+/K+-ATPase inhibitor. Proscillaridin A can increase intracellular Ca2+ concentration, activate caspase-3 and induce apoptosis in human fibroblasts. NÚMERO DE CAS 466-06-8

(+)-Brefeldin Asc-364105 NÚMERO DE CAS 20350-15-6

EGTA/AMsc-203937EGTA/AM is a membrane-permeable form of the EGTA Ca2+-chelating agent. NÚMERO DE CAS 99590-86-0

Busulfansc-204658Antineoplastic bifunctional, DNA alkylating agent that causes DNA damage by cross-linking DNA and proteins. Causes double-base lesions mainly at 5’-GA-3’ and, to a lesser extent, at 5’-GG-3’ sequences. Forms an intrastrand cross-link at the 5’-GA-3’ sequence, and to monoalkylation. Induces normal human fibroblast senescence selectively through Erk and p38 pathways. NÚMERO DE CAS 55-98-1

Rottlerinsc-3550Rottlerin is an inhibitor of eEF2K, PKCδ, PKCα, PKCβ, PKCε, PKCη and PKCζ, but with significantly reduced potency. It is also a HERG activator. NÚMERO DE CAS 82-08-6

4
Gambogic Acid sc-200137Gambogic Acid induces apoptosis without affecting the cell cycle and inhibits Bcl-2 family proteins. Gambogic Acid targets CD71 (transferrin receptors) and activates caspases. NÚMERO DE CAS 2752-65-0

C2 Ceramide (N-Acetylsphingosine, D-erythro)sc-201375C2 Ceramide is a cell-permeable ceramide and potent modulator of cell proliferation and differentiation. Potential activator of ERK 2, PP1, and PP2. NÚMERO DE CAS 3102-57-6

1
Staurosporinesc-3510Staurosporine inhibits PKC and most other kinases, including tyrosine kinases; binds to ATP binding domain; inhibits topoisomerase II. NÚMERO DE CAS 62996-74-1

16
C75sc-202511C75 is an inhibitor of fatty acid synthase (FAS) reducing food intake and body weight in mice. NÚMERO DE CAS 191282-48-1

CD 2665sc-293988A selective RARβ/γ antagonist (KD values are 110, 306 and > 1000 nM for RARγ, RARβ and RARα respectively). Shown to block retinoic acid-induced apoptosis ex vivo NÚMERO DE CAS 170355-78-9

MK-886 sodium saltsc-200608MK-886 sodium salt, also designated L-663,536, is a potent and selective inhibitor of FLAP (5-lipoxygenase-activating protein). NÚMERO DE CAS 118427-55-7

CD 437sc-202527CD 437 is a synthetic, cell-permeable, retinoid-related molecule that induces tumor growth arrest and apoptosis. NÚMERO DE CAS 125316-60-1

Triptolide (PG490)sc-200122Triptolide (PG490) is an immunosuppressive, antiinflammatory antibiotic from Tripterygium wilfordii Hook F herb extracts. It activates caspases, promoting apoptosis in T lymphocytes and rheumatoid synovial fibroblasts. NÚMERO DE CAS 38748-32-2

1
Droxinostatsc-364485Droxinostat is a selective inhibitor to HDAC3, HDAC6, and HDAC8, and sensitizes various cancer cells to apoptosis. NÚMERO DE CAS 99873-43-5

Chaetocinsc-200893Chaetocin is an inhibitor of lysine-specific histone methyltransferase effects, which are essential for gene expression patterns during cell differentiation. Also reported to induce apoptosis in some murine cancer cells. NÚMERO DE CAS 28097-03-2

HC Toxinsc-200884HC Toxin is a potent, cell-permeable HDAC (histone deacetylase) inhibitor. HC Toxin inhibits HDACs in maize, Physarum and chicken. NÚMERO DE CAS 83209-65-8

Valinomycinsc-200991Valinomycin is a dodecadepsipeptide and potassium ionophore shown to induce cell death. It has been reported to promote hemolysis in HK erythrocytes and cell death in CHO cells. NÚMERO DE CAS 2001-95-8

Ingenolsc-202184Extremely weak protein kinase C (PKC) activator. Has been found to induce apoptosis and act as an anticancer agent. Ingenol derivatives have received constant and multidisciplinary attention on account of their pleiotropic pattern of biological activity. This includes activation of protein kinase C (PKC), tumour-promotion, anticancer, and anti-HIV properties, and the possibility of dissecting co-cancerogenic and clinically useful activities has been demonstrated. Certain ingenol esters show powerful anticancer activity, and a structure-activity relationship model to discriminate between their apoptotic and non-apoptotic properties has been developed. NÚMERO DE CAS 30220-46-3

Chlorambucilsc-204682A nitrogen mustard bifunctional alkylating agent. Displays antineoplastic and immunosuppressant effect. Induces apoptosis in chronic lymphocytic leukemia cells. NÚMERO DE CAS 305-03-3

Irinotecan Carboxylate Sodium Saltsc-280848Irinotecan Carboxylate Sodium Salt is the carboxylate form of Irinotecan (sc-202186),

10058-F4sc-21357710058-F4 is a c-Myc inhibitor that prevents c-Myc/Max dimerization. Also shown to arrest cell growth at G0/G1 phase and eventually lead to apoptosis. NÚMERO DE CAS 403811-55-2

Zoledronic acidsc-364663Zoledronic acid is an activator of protein kinase C with apoptotic effects on multiple myeloma cell lines. NÚMERO DE CAS 118072-93-8

Exotoxin A, Pseudomonas aeruginosasc-203949Exotoxin A, Pseudomonas aeruginosa is a bacterial toxin originally derived from Pseudomonas aeruginosa that has been shown to arrest protein synthesis and cause apoptosis. NÚMERO DE CAS 91262-95-2

Zearalenonesc-204943Zearalenone, is a phytoestrogenic mycotoxin usually produced by Fusarium species. It is also shown to be an anti-proliferative agent that causes mitochondrial release of Cytochrome c and production of ROS. NÚMERO DE CAS 17924-92-4

Z-DEVD-pNAsc-296747Z-DEVD-pNA is a caspase-3 chromogenic substrate with increased cell permeability. It is also a substrate for caspase-1,caspase-4 and caspase-7.

CHM-1sc-214686CHM-1 is a potent, selective antitumor agent in human hepatocellular carcinoma. CHM-1 induces apoptosis, and it binds tubulin and inhibits tubulin polymerization. NÚMERO DE CAS 154554-41-3

cis-3,4',5-Trimethoxy-3'-aminostilbenesc-217910A Resveratrol derivative which shows apoptotic activity at nanomolar concentrations. Has an IC50= 0.3. It showed activity toward resistant HL60R cells and their activity was higher than that of several classic chemotherapeutic agents. NÚMERO DE CAS 586410-12-0

Ceramide C6sc-3527Ceramide C6 has shown to activate MAP kinase (ERK) and PP2A along with apoptosis of Molt-4 and HL-60, enhance COX-2 in rats and aortic smooth muscle in bovines. NÚMERO DE CAS 124753-97-5

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Citrininsc-358726Antibiotic which induces mitochondrial permeability pore opening and inhibits respiration by interfering with complex I of the respiratory chain. Mycotoxin acting as nephrotoxin in all species in which has been tested. Been implicated as a cause of Balkan nephropathy and yellow rice fever in humans. Also induces apoptosis. NÚMERO DE CAS 518-75-2

Costunolidesc-203555A sequiterpene lactone isolated from Magnolia sieboldii. Described to act as an antioxidant, anti-mycobacterial, anti-inflammatory, and anti-viral, with cytotoxic activity. NÚMERO DE CAS 553-21-9

Clodronate, Disodium Saltsc-202547A first-generation bisphosphonate and strong inhibitor of osteoclast-mediated bone resorption. Contains cytotoxic effects towards macrophages. NÚMERO DE CAS 22560-50-5

Colcemidsc-202550A cell synchronizing agent that induces coordination of nuclear and cytoplasmic events during cell growth. Also an anti-tubulin agent which blocks cell growth at the mitotic level. NÚMERO DE CAS 477-30-5

Colchicinesc-203005Colchicine is an apoptosis reagent that affects microtubule polymerization and disrupts cytoskeletal formation. Colchicine is also known to interfere with tissue plasminogen activators. NÚMERO DE CAS 64-86-8

Concanavalin Asc-203007A plant lectin that is a T cell mitogen. It induces apoptosis in human fibroblasts. NÚMERO DE CAS 11028-71-0

CX-4945sc-364475CX-4945 is an ATP-competitive CK2 protein kinase inhibitor with anti-proliferative properties against certain cancerous cell lines. NÚMERO DE CAS 1009820-21-6

Camptothecinsc-200871Camptothecin reversibly inhibits Mitochondrial Topo I (nuclear Topo I), inhibits Tat-mediated transactivation of HIV-1 and exhibits intense blue fluorescence when exposed to UV light. NÚMERO DE CAS 7689-03-4

8
Pirarubicinsc-205810Pirarubicin is an analogue of the anthracycline anti-neoplastic doxorubicin (sc-280681). Intercalates into DNA and interacts with Topo II (topoisomerase II) and supressing DNA replication. NÚMERO DE CAS 72496-41-4

Adenosinesc-291838Adenosine is neurotransmitter that acts as the preferred endogenous agonist at all adenosine receptor subtypes. It induces apoptosis in human leukemia HL-60 cells. NÚMERO DE CAS 58-61-7

Cyclophosphamidesc-361165Cyclophosphamide has been reported to be an anti-proliferative agent that regulates Bax and Bcl-2 expression. This compound also inhibits aldehyde dehydrogenase 1 through its degradation product acrolein. NÚMERO DE CAS 50-18-0

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance Psc-361166[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P has been shown to be a broad spectrum neuropeptide antagonist and inverse agonist. This compound has also been reported to be a potent full inverse agonist for the ghrelin receptor (GHS-R1). NÚMERO DE CAS 96736-12-8

Cyclophosphamide Monohydratesc-202117A widely used antineoplastic agent that also displays immuno-suppressant activity. Induces apoptotic cell death in rat thymus throught Fas/Fas ligand pathway. NÚMERO DE CAS 6055-19-2

3
D-erythro-N,N-Dimethylsphingosinesc-201373D-erythro-N,N-Dimethylsphingosine inhibits SphK (sphingosine kinase), blocking the conversion of sphingosine to sphingosine-1 phosphate. NÚMERO DE CAS 119567-63-4

Canavanine sulfatesc-202983Canavanine sulfate is reported to be a selective inhibitor of NOS2 (iNOS) due to its structural mimicry of the native NOS2 substrate L-arginine. NÚMERO DE CAS 2219-31-0

M 344sc-203124M344 is a potent HDAC inhibitor with IC50 of 100 nM. NÚMERO DE CAS 251456-60-7

8
D-α-Tocopheryl Succinatesc-200141D-α-Tocopheryl Succinate is an apoptosis agent that triggers caspase-mediated apoptosis at high concentrations and prevents cell proliferation at low concentrations. NÚMERO DE CAS 4345-03-3

Daunorubicin • HCl (Daunomycin • HCl)sc-200921Daunorubicin (Daunomycin) is a DNA intercalating anthracylcine natural product. Reported to demonstrate anti-proliferative activity against certain leukemias. NÚMERO DE CAS 23541-50-6

Fumonisin B2sc-201393Fumonisin B2 is a structural analog of fumonisin B1 noted to inhibit LASS (sphingosine acyltransferase). NÚMERO DE CAS 116355-84-1

Dexamethasone Sodium Phosphatesc-204715A systemic corticosteroid. It induces apoptosis and inhibits sodium phosphate symporter. Used in the treatment of emetic effects of cancer therapy and epicondylitis. NÚMERO DE CAS 2392-39-4

Actinoninsc-201289Actinonin is an antibiotic shown to inhibit aminopeptidases, PDF (peptide deformylase), meprin A, CD 13 and MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-12 and MMP-13. NÚMERO DE CAS 13434-13-4

Dicoumarolsc-205647Reductase inhibitor possessing anticoagulant properties. Aids in apoptosis induction via stimulation of SAPK-JNK and NF-κB pathway blocking. This has no effect on the phosphorylation of P38 or activation of AKT. Also shown to block brefeldin A-dependent mono-ADP-ribosylation in vitro and Golgi disassembly in living cells. NÚMERO DE CAS 66-76-2

4
Diethylstilbestrolsc-204720A synthetic estrogen that induces apoptosis in hormone-insensitive prostate cancer cells. NÚMERO DE CAS 56-53-1

Difluoromethylornithinesc-204723An irreversible inhibitor of ornithine decarboxylase which has antiangiogenic activity, inhibits carcinogenesis and induces apoptosis. NÚMERO DE CAS 67037-37-0

Perillic Acidsc-200841Shown to elicit cytotoxicity, induce cell cycle arrest, and apoptosis via an increase in expression of p21, Bax, and caspase-3 in cells. Also has been reported to be a major metabolite of d-limonene. NÚMERO DE CAS 23635-14-5

DMXAAsc-207592Apoptosis inducer. Anti-vascular. NÚMERO DE CAS 117570-53-3

SB 202190sc-202334SB 202190 is a pyridinyl imidazole that inhibits the p38 pathway. It can also induce apoptosis, and phosphorylate and activate MLK3. NÚMERO DE CAS 152121-30-7

2
Docetaxelsc-201436A semi-synthetic analog of Taxol. Stabilizes microtubules and inhibits mitosis, leading to apoptosis. NÚMERO DE CAS 114977-28-5

1
Dolastatin 15sc-201449Dolastatin 15 is a marine natural product with anti-neoplastic, Tubulin inhibitor, hematopoietc progenitor cell inhibitor, as well as immunoglobulin production and leukemia cell proliferation inhibitor. NÚMERO DE CAS 123884-00-4

Eeyarestatin Isc-358130An endoplasmic reticulum associated degradation inhibitor that suppresses protein translocation and therefore limits the elimination of misfolded proteins from the ER. NÚMERO DE CAS 412960-54-4

Enhancer for Receptorssc-221586

Enzastaurinsc-364488Enzastaurin is a growth inhibitor to all MM cell lines and induces apoptosis in certain tumor cell lines. NÚMERO DE CAS 170364-57-5

(-)Epicatechin gallatesc-204739A polyphenol apoptosis inducer in tumor cells commonly found in green tea. Studies suggest that (-)Epicatechin gallate causes anti-proliferative and anti-inflammatory effects on pancreatic ductal adenocarcinoma cells. NÚMERO DE CAS 1257-08-5

1
Erucinsc-204741An isothiocyanate from cruciferous vegetable. It is effective inapoptosis induction and mitochondrial potiential dissipation. NÚMERO DE CAS 4430-36-8

Topotecan Hydrochloridesc-204919Topotecan Hydrochloride is a topoisomerase I (Topo I) inhibitor. A water-soluble semisynthetic derivative of Camptothecin (sc-200871). Stabilizes Topo I/DNA cleavable complexes. NÚMERO DE CAS 119413-54-6

Estrensc-204745Estren is a steroid ligand that exhibits lower binding affinity for estrogen receptor and has no classical transcriptional activity. NÚMERO DE CAS 35950-87-9

Topotecan Hydrochloride Labeled d6sc-356167Topotecan Hydrochloride Labeled d6 is an isotope labeled Topo I (topoisomerase I) inhibitor. NÚMERO DE CAS 119413-54-6 (unlabeled)

Farnesolsc-204748Polyprenyl alcohol found in plant essential oils. Induces apoptosis in cell cultures. NÚMERO DE CAS 4602-84-0

1
Fludarabinesc-204755Prodrug converted to free nucleoside 9-β-D-arabinosyl-2-fluoroadenine (F-ara-A). F-ara-A enters cells and accumulates as 5’-triphosphate. Interferes with DNA synthesis and repair. Induces apoptosis of cancer cells and RNA transcription inhibitor. NÚMERO DE CAS 21679-14-1

Folic Acidsc-204758Important cofactor in the transfer of one-carbon moieties and plays big role in formation of S-adenosyl methionine and in the synthesis and repair of DNA and RNA. NÚMERO DE CAS 59-30-3

Gemcitabine Hydrochloridesc-204763Gemcitabine Hydrochloride is a ribonucleotide reductase inhibitor (R1 and R2). NÚMERO DE CAS 122111-03-9

1
Myriocin (ISP-1)sc-201397Myriocin is a small molecule inhibitor of SPTLC (serine palmitoyltransferase), necessary for sphingolipid biosynthesis. A tool for depleting cells of sphingolipids. NÚMERO DE CAS 35891-70-4

Gingerolsc-201519Shown to activate cardiac and skeletal SR Ca2+-ATPase with apoptosis inducing, antiinflammatory, and antioxidant characteristics. NÚMERO DE CAS 23513-14-6

Hexamethonium bromide hydratesc-205712A nicotinic acetyl choline receptor antagonist. Induces apoptosis and inhibits the stimulatory effect of nicotine on endothelial cell DNA synthesis and proliferation. Also effective in preventing organophosphate intoxication. NÚMERO DE CAS 55-97-0

Hexamethylene Biscetamidesc-204772Prototype of hybrid polar inducers of apoptosis of various transformed cells. NÚMERO DE CAS 3073-59-4

Hinokitiolsc-200812Hinokitiol is a potent iron chelator that inhibits UV B-induced apoptosis in keratinocytes of murine skin. Also demonstrates antimicrobial characteristics. NÚMERO DE CAS 499-44-5

HMBAsc-300799HMBA is an inhibitor of microtubule polymerization that interacts with tubulin. It is also an apoptosis inducer that exhibits potent antitumor activity.

Homoharringtoninesc-202652Cephalotaxine alkaloid. Inhibits the formation of diphenylalanine and acetylphenylalanyl-puromycin in liver ribosomes. Has promising activity in hematologic malignancies. Lowers telomerase levels. NÚMERO DE CAS 26833-87-4

Idarubicin Hydrochloridesc-204774A hydrochloride salt preparation of Idarubicin and an anthracycline analog of daunorubicin. Shown to be an apoptosis inducer that triggers ROS production. NÚMERO DE CAS 57852-57-0

Okadaic Acidsc-3513Okadaic acid is a potent and selective inhibitor of PP1 and PP2A-C (PP2A phosphatases); reduces outgrowth of PC12 cells. NÚMERO DE CAS 78111-17-8

10
Sulindac Sulfidesc-200118Sulindac Sulfide, a metabolite of Sulindac (sc-202823), is a non-steroidal anti-inflammatory compound that demonstrates inhibition of Cox, Ras, and γ-secretase. NÚMERO DE CAS 32004-67-4

1
Indanocinesc-221750A potent cytostatic and cytotoxic indanone that inhhibits tubulin polymerization. Induces apoptotic cell death in stationary-phase multidrug-resistant cancer cells. NÚMERO DE CAS 225652-60-8

Ionomycinsc-3592Ionomycin (Ca) is a highly selective and potent calcium ionophore which serves as a useful tool for increasing intracellular Ca2+ concentrations. A non-fluorescent antibiotic and more effective than A23187 (sc-3591). NÚMERO DE CAS 56092-82-1

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Iron Chelator, Dp44mTsc-221764A cell-permeable di-2-pyridyl thiosemicarbazone (DpT) based tridentate ligand that displays potent and selective antiproliferative properties in neoplastic cells and minimally affects normal cells. Prevents aggressive growth of M109 lung carcinoma in mice. Shown to mobilize cellular iron effectively, and generate ROS leading to apoptosis.

Romidepsinsc-364603Romidepsin strongly inhibits HDAC1 and HDAC2 with IC50 of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6. NÚMERO DE CAS 128517-07-7

Isoapoptolidinsc-202187A ring expanded isomer of apoptolidin. In water, an equilibrium mixture of apoptolidin:isoapoptolidin (~1.5:1) is formed within hours. Used for F0F1-ATPase assays. NÚMERO DE CAS 476647-30-0

Tenovin-1sc-222342Tenovin-1 is a compound that belongs to the class of Tenovins, and inhibits SIRT1 and SIRT2. NÚMERO DE CAS 380315-80-0

ITF2357sc-364513ITF2357 reduces the release of NFα, IL-1α, IL-1β, and IFNγ, in PBMCs, activating apoptotic pathways. NÚMERO DE CAS 732302-99-7

Jasplakinolidesc-202191Jasplakinolide is a macrocyclic peptide natural product from the marine sponge Jaspis johnstoni which induces the polymerization of actin into filaments (F-actin). NÚMERO DE CAS 102396-24-7

Glycodeoxycholic Acid, Sodium Saltsc-280755Glycodeoxycholic Acid, Sodium Salt induces apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. NÚMERO DE CAS 16409-34-0

Kainic acidsc-200454An agonist of the glutamate-recognizing ionotropic kainate receptors. Employed as a tool for inducing excitotoxicity and producing seizures in neurotransmission models. NÚMERO DE CAS 487-79-6

9
L-Sulforaphanesc-203099An inducer of apoptosis, phase II detoxification enzyme, as well as xenobiotic enzymes. Also shown to inhibit strains of Helicobacter pylori. NÚMERO DE CAS 142825-10-3

Scriptaidsc-202807Scriptaid is an HDAC inhibitor (histone deacetylase). Nullscript (sc-222084) serves as the negative control for Scriptaid. NÚMERO DE CAS 287383-59-9

1
LE 135sc-204053LE 135 is a retinoic acid receptor antagonist which displays moderate selectivity for RARβ over RAR&alpha NÚMERO DE CAS 155877-83-1

Bafilomycin B1sc-202072Bafilomycin B1 has been shown to be a potent and specific inhibitor of vacuolar (V-type) ATPase enzymes and displays antifungal characteristics. NÚMERO DE CAS 88899-56-3

Lipopolysaccharide, Salmonella typhimuriumsc-221857Lipopolysaccharide, Salmonella typhimurium stimulates the activity of inducible nitric oxide synthase. Also induces apoptosis in mouse thymus and swine lymphocytes. Contaminants: protein 1.5%; nucleic acid; 1.2%.

Sodium Butyratesc-202341Sodium Butyrate has been reported to cause hyperacetylation of histones due to its role as an HDAC (histone deacetylase) inhibitor. NÚMERO DE CAS 156-54-7

7
Methylprednisolonesc-205749An apoptosis inducer used in the treatment of lupus nephritis and was also found to inhibit human small cell lung cancer cell growth. NÚMERO DE CAS 83-43-2

Mitomycin C (4% in NaCl)sc-286964A reagent used to generate mitotically inactive feeder cells in culture. Mitomycin C (4% in NaCl) is a DNA crosslinking agent which inhibits DNA synthesis and causes apoptosis via a p53-dependent pathway. NÚMERO DE CAS 50-07-7 (non-salt)

Narciclasinesc-361271Exhibits antiproliferative and pro-apoptotic effects in carcinoma cells and displays cytotoxic activity against a panel of 60 cancer cell lines (mean IC50 = 47 nM). Activity decreases rate of cell division and increases mitosis duration in vitro. Also modulates the Rho/ROCK/LIM kinase/cofilin pathway; stimulates RhoA activation and induces actin polymerization. NÚMERO DE CAS 29477-83-6

Necrosis Inhibidor, IM-54sc-222053Necrosis Inhibitor, IM-54 is a cell-permeable mono-indolylmaleimide compound that selectively blocks oxidative stress-induced necrotic cell death . NÚMERO DE CAS 861891-50-1

Nigericin•Nasc-201518Nigericin, a polyether antibioitc K+ and Na+ ionophore, stimulates Ca2+ release from mitochondria and stimulates ATPase activity. NÚMERO DE CAS 28380-24-7

1
Valproic Acid, Sodium Saltsc-202378Valproic Acid, Sodium Salt is a potent inhibitor of HDAC (histone deacetylase) in vitro (IC50 = 400 μM for HDAC1). NÚMERO DE CAS 1069-66-5

4
Oligomycinsc-203342A macrolide that acts as a specific inhibitor of the mitochondrial ATP-synthase and blocks oxidative phosphorylation. NÚMERO DE CAS 1404-19-9

Oncrasin 1sc-204146Proapoptotic substance. Induces abnormal nuclear aggregation of PKCι and suppressing RNA transcription. Displays antiproliferative effects against various human tumor cell lines. Shown to inhibit human xenograft growth by 75% in vivo. NÚMERO DE CAS 75629-57-1

PAC 1sc-203174PAC 1 is a procaspase-activating compound, which induces the production of caspase-3. Caspases play a role in regulating apoptosis by cleaving proteins that are vital to cell viability. NÚMERO DE CAS 315183-21-2

1
(-)-Perillyl Alcoholsc-205798A monoterpene derived from Lavender, that induces apoptosis in colon tumor cells. Inhibits mammary cancer by inducing hepatocyte phase II enzymes, glutathione-S-transferase. NÚMERO DE CAS 18457-55-1

(+)-Perillyl alcoholsc-362189 NÚMERO DE CAS 57717-97-2

Phenylethyl 3-methylcaffeatesc-205804Has chemopreventive property against chemically induced colon carcinogenesis. Also amplifies apoptosis in azoxymethane induced colon tumors. NÚMERO DE CAS 71835-85-3

PPAHVsc-202296PPAHV is a non-pungent resiniferatoxin-type phorboid vanilloid. NÚMERO DE CAS 175796-50-6

Pregnenolonesc-204860Endogenous neurosteroid that inhibits GABA-gated chloride currents by enhancing receptor desensitization. Modulates NMDA receptors resulting in delayed apoptotic retinal cell death.Stimulates prostate LNCaP cell proliferation through binding to the mutated androgen receptor. NÚMERO DE CAS 145-13-1

R(-) Iberinsc-364348

Raltitrexed monohydratesc-311520This is a folate-based inhibitor of thymidylate synthase (TS) that is rapidly metabolized to its more potent polyglutamate derivatives.

Reveromycin Asc-202314The dominant analogue of a complex of spiroketals isolated from Streptomyces. Inhibits the mitogenic activity of EGF. G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. NÚMERO DE CAS 134615-37-5

1
Rocaglamide Csc-202793A derivative of Rocaglamide with apoptotic effects on leukemic cells, leukemic T cells, inhibiton of NF-κB in non-leukemic T cells as well as insecticide activity towards the larvae Spodoptera littoralis. NÚMERO DE CAS 189322-67-6

(±)-S-Nitroso-N-acetylpenicillamine (SNAP)sc-200319(±)-S-Nitroso-N-acetylpenicillamine (SNAP) is a cysteine protease inhibitor and NO donor which spontaneously releases NO under physiological conditions. NÚMERO DE CAS 79032-48-7

3
Rocaglaolsc-202322An active derivative of rocaglamide. The compound has antifungal activity and can induce apoptosis and cell cycle arrest in LNCaP cells. NÚMERO DE CAS 147059-46-9

1
(S)-a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acidsc-203250An active enantiomer of AMPA ((R,S)-AMPA) that induces apoptotic cell death in cortical neurons. Does not exhibit any affinity for NMDA receptors. NÚMERO DE CAS 83643-88-3

S-Nitrosoglutathione (GSNO)sc-200349S-Nitrosoglutathione (GSNO) inhibits platelet activation and displays cardioprotective effects. Inhibits NF-κB activation and endothelial cell proliferation. Shows a dose dependent effect on Thymocyte apoptosis. NÚMERO DE CAS 57564-91-7

S14161sc-364134 NÚMERO DE CAS 883046-50-2

Saikosaponin Dsc-301786Saikosaponin D inhibits cell growth of human cancer cells by inducing apoptosis and blocking cell cycle progression in the G1 phase. Saikosaponin D was found to stimulate corticotropin-releasing factor (CRF) gene expression and CRF release. NÚMERO DE CAS 20874-52-6

4-Hydroxynonenalsc-2020194-Hydroxynonenal has been shown to irreversibly inhibit Na+-K+-ATPase activity. Also an inhibitor of JNK and an activator of ANKTM1. NÚMERO DE CAS 75899-68-2

3
SU11652sc-204310SU11652 is a potent cell-permeable pyrrole-indolinone compound that acts as an ATP-competitive tyrosine kinase receptor and angiogenic inhibitor NÚMERO DE CAS 326914-10-7

Sulindac Sulfonesc-200120Sulindac Sulfone induces apoptosis but does not inhibit Cox (cyclooxygenase). Sulindac Sulfone is a metabolite of Sulindac (sc-202823). NÚMERO DE CAS 59864-04-9

2
Taxolsc-201439Taxol is an antineoplastic and microtubule affecting agent that causes apoptotic cell death, internucleosomal DNA fragmentation, and inhibition of protein isoprenylation. NÚMERO DE CAS 33069-62-4

Teniposidesc-204910Glycoside-derivative of podophyllotoxin. Has cytostatic effect. Inhibits topoisomerase II while induces apoptosis. NÚMERO DE CAS 29767-20-2

Tetracyclinesc-205858Used for treatment of chronic inflammatory cells. Tetracycline derivatives induce apoptosis in osteoclasts, Jurkat T lymphocyte cells and in cultured monocytes and macrophages. NÚMERO DE CAS 60-54-8

Ro 31-8220sc-200619Ro 31-8220 is a cell-permeable PKC inhibitor, that is selective for PKC-α, PKC-βI, PKC-βII, PKC-γ, and PKC-&epsilon isoforms. Shown to induce apoptosis in a variety of cell lines, and inhibit glycogen synthase kinase 3. NÚMERO DE CAS 138489-18-6

1
Thiocolchicinesc-202838Inhibitor of microtubules by specific binding to tubulin. Modulator of axonal cytoskeleton. Induces apoptosis. Topoisomerase I inhibitor. NÚMERO DE CAS 2730-71-4

TPENsc-200131TPEN is a cell permeable, high-affinity heavy metal chelator that exhibits low affinity for Mg2+ and Ca2+. TPEN is a useful tool for chelation of intracellular Zn2+. NÚMERO DE CAS 16858-02-9

Triamcinolonesc-204924A glucocorticoid capable of sustaining neuromuscular transmission during early motor nerve degeneration. It is also known to induce apoptosis in T lymphocytes. NÚMERO DE CAS 124-94-7

Tubeimoside Isc-204931A triterpenoid saponin isolated from tubers of bolbostemma paniculatum, Franquet, a traditional Chinese medicine "Tu-Bei-Mu". Used as anti-tumor agent, induces cell cycle arrest and apoptosis. NÚMERO DE CAS 102040-03-9

UA62784sc-216036A fluorenone specific inhibitor of CENP-E (centromere protein E), which is a kinesin-like motor protein. Induces cell cycle arrest via inhibiting chromosome congregation at the metaphase plate. NÚMERO DE CAS 313367-92-9

VER-49009sc-357409A pyrazole compound that inhibits Hsp90 with an IC50 value of 47 nM; produces a cellular antiproliferative GI50 value of 685 nM when tested against a human cancer cell line panel. NÚMERO DE CAS 940289-57-6

Vincristine Sulfatesc-201434Vincristine Sulfate has been shown to bind Tubulin via a protein self association reaction. Vincristine Sulfate has also shown to contain anti-proliferative characteristics via induction of apoptosis of cells. NÚMERO DE CAS 2068-78-2

2
Xanthorrhizolsc-202855An antibacterial and an anti-inflammatory compound that can induce apoptosis. NÚMERO DE CAS 30199-26-9

1
6-ECDCAsc-2805386-ECDCA, or 6-Ethylchenodeoxycholic acid, is a cholic acid derivative which behaves as a potent and selective FXR (farnesoid X receptor) agonist. NÚMERO DE CAS 459789-99-2

Lipopolysaccharide, Salmonella minnesota Re 595sc-221856Lipopolysaccharide, Salmonella minnesota Re 595 is an activator of TLR4.

Chrysinsc-204686Chrysin is an antioxidant flavonoid. Chrysin displays anti-inflammatory and antitumor properties. Chrysin inhibits HIF-1α (hypoxia-inducible factor-1α) and induces apoptosis. NÚMERO DE CAS 480-40-0

Morinsc-205955Antioxidant flavonoid. Shows anti-proliferative and antitumor properties. Induces apoptosis. Induces cell cycle arrest at the G2/M phase. Anti-inflammatory compound. Suppresses NF-κB activation. Induces lipid peroxidation and DNA strand breaks. NÚMERO DE CAS 654055-01-3

17-AAGsc-20064117-AAG is an HSP 90 inhibitor that displays a 100-fold higher affinity for HSP 90 derived from tumor cells compared to HSP 90 from normal cells. 17-AAG is an inhibitor of K-Ras and N-Ras. NÚMERO DE CAS 75747-14-7

Cyproterone Acetatesc-204703A hepatomitogen and tumor promoter. Induces apoptosis in hepatocytes. NÚMERO DE CAS 427-51-0

MT-21sc-221959MT-21 is an activator of caspase-3, JNK and Krs.

Deguelinsc-200657Deguelin inhibits AKT by both PI 3-kinase dependent and PI 3-kinase independent pathways. It has also been shown to inhibit Cox-2 expression. NÚMERO DE CAS 522-17-8

Buteinsc-202510Butein is a plant polyphenol which acts as a specific protein tyrosine kinase inhibitor which potently inhibits the EGF receptor. Also inhibits IKK, GST, CYP19, and glutathione reductase. NÚMERO DE CAS 487-52-5

Mastoparan (Vespula lewisii)sc-200831Mastoparan (Vespula lewisii) has been shown to be capable of directly activating G proteins by a mechanism analogous to that of G protein-coupled receptors. Also found to stimulate insulin release by pancreatic islets. NÚMERO DE CAS 72093-21-1

Disulfiramsc-205654Disulfiram inhibits ALDH (aldehyde dehydrogenase). NÚMERO DE CAS 97-77-8

Embelinsc-201555Embelin has been shown to be an antinociceptive and antiinflammatory agent with antioxidative capabilities. This compound has also been reported to induce apoptosis. NÚMERO DE CAS 550-24-3

1
Sphingosine Kinase Inhibidorsc-208400Sphingosine Kinase Inhibitor is an inhibitor of SphK. NÚMERO DE CAS 1177741-83-1

Geranylgeraniolsc-200858Geranylgeraniol, is an intermediate in the mevalonate pathway, that has been shown to prevent bone re-adsorption, inhibition of osteoclast formation, and kinase activation in vitro. NÚMERO DE CAS 24034-73-9

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Temozolomidesc-203292An antitumor and antiangiogenic compound that is believed to work by alkylating DNA, thereby triggering apoptosis. NÚMERO DE CAS 85622-93-1

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Quinomycin Asc-202306Quinomycin A exhibits various antibiotic, antiviral, and antitumor activity. Quinomycin A reportedly inhibits HIF by blocking binding of HIF-1α and HIF-1β proteins to a HRE sequence. NÚMERO DE CAS 512-64-1

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Tubulin Polymerization Inhibidorsc-222377Tubulin Polymerization Inhibitor is a low molecular weight, cell-permeable, benzylidene-anthracenone antimicrotubule agent that exhibits potent antitumor activity.

MG-115sc-221940A potent, reversible proteasome inhibitor. MG-115 specifically inhibits the chymotrypsin-like activity of the proteasome. NÚMERO DE CAS 133407-86-0

TNF-α Antagonist III, R-7050sc-356159TNF-α Antagonist III, R-7050 has been reported to act as a TNF-α receptor antagonist. It also selectively inhibit TNF-α-, but not Fas- or C6-ceramide induced caspase activation and cell death. NÚMERO DE CAS 303997-35-5

Honokiolsc-202653Honokiol is a biphenyl neolignan and active part of Magnolia extract that inhibits phosphorylation of Akt, p44/42 mitogen-activated protein kinase (MAPK), and src. NÚMERO DE CAS 35354-74-6

20-Hydroxyecdysonesc-20240720-Hydroxyecdysone is the most widely occurring ecdysteroid in both plant and animal species. Controls cell death during metamorphosis of Drosophila melanogaster. NÚMERO DE CAS 5289-74-7

Concanamycin Bsc-221434An antibiotic that specifically inhibits vacuolar type H+-ATPase. Also has been shown to cause destruction of cytotoxic granules and inhibition of acidification of intracellular organelles. NÚMERO DE CAS 81552-33-2

Nutlin-3sc-45061Nutlin-3, the most commonly used form of nutlin exhibits potent antiproliferative activity in cells with functional p53, but not in cells with mutated p53 NÚMERO DE CAS 548472-68-0

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Noscapine hydrochloridesc-203650Noscapine hydrochloride is a bradykinin B receptor inhibitor and tubulin inhibitor. NÚMERO DE CAS 912-60-7

P-Glycoprotein Inhibidor, C-4sc-222109P-Glycoprotein Inhibitor, C-4 is a cell-permeable cinnamoyl compound that inhibits Mdr-1 (P-gp). This in turn inhibits cellular efflux of active compounds, effectively reversing multidrug resistance in cells.

Indirubin-3'-monoximesc-202660Indirubin-3'-monoxime is a potent inhibitor of GSK-3β, CDK1, CDK5, and reversibly arrests asynchronous HBL-100 cells at G22. NÚMERO DE CAS 160807-49-8

PIT 1sc-361293This compound is an apoptosis inducing selective PIP3 antagonist. NÚMERO DE CAS 53501-41-0

Reveromycin Csc-202316A member of the Reveromycin antibiotic family isolated from Streptomyces culture broth. Demonstrates inhibition of mitogenic activity in response to EGF signaling. NÚMERO DE CAS 144860-69-5

β-Sitosterolsc-204432β-Sitosterol is a common plant steroid that possesses anticholesteremic properties. NÚMERO DE CAS 83-46-5

RGD péptido (GRGDNP)sc-201176RGD peptide (GRGDNP) is an inhibitor of integrin-ligand interactions. It can induce apoptosis in the absence of signals and integrin-mediated cell clustering. NÚMERO DE CAS 114681-65-1

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SJ 172550sc-357403SJ 172550 is an MDMX inhibitor which reversibly binds MDMX and inhibits MDMX-p53 interaction in cell cultures. NÚMERO DE CAS 431979-47-4

Sulindacsc-202823Sulindac inhibits the NF-κB pathway. Sulindac metabolizes to sulindac sulfide (sc-200118), a Cox (cyclooxygenase) inhibitor, and sulindac sulfone (sc-200120). NÚMERO DE CAS 38194-50-2

Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3)sc-200766Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) (EPA) inhibits amino acid oxygenation by PG endoperoxide H synthase-1 and 5-LO (5-lipoxygenase). NÚMERO DE CAS 10417-94-4

Curcumin (Synthetic)sc-294110Major curcumoid isolated from tumeric with antioxidant, anticancer and anti-inflammatory activities. Reported to supress NF-κB, COX-1, COX-2 and TNF-α. Upregulates PPARγ, p53 and Nrf2. NÚMERO DE CAS 458-37-7

Δ12-PGJ2 (Δ12-Prostaglandin J2) sc-201257δ12-PGJ2 (δ12-Prostaglandin J2) is decomposition product of PGD2 (sc-201221) that has shown potent antiviral and anti-proliferative activity, and has also been shown to induce apoptosis, and to inhibit phosphoinositide turnover. NÚMERO DE CAS 87893-54-7

Dihydrokainic acidsc-200442Dihydrokainic acid is an EAAT2 (GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake. NÚMERO DE CAS 52497-36-6

PGA2 (Prostaglandin A2)sc-201215Shown to possess antitumor activity, induce γ-glutamylcysteine synthetase and apoptosis in L-1210 cells, and to activate intrinsic apoptotic pathways by directly stimulating mitochondrial outer membrane permeabilization. NÚMERO DE CAS 13345-50-1

eIF4E/eIF4G Interaction Inhibidor, 4EGI-1sc-202597Reported to inhibit cap-dependent protein translation and also induce apoptosis in cells via down-regulations of FLIPS/L and induction of DR5. NÚMERO DE CAS 315706-13-9

RO-3306sc-358700RO-3306 is shown to be an inhibitor of CDK1/cyclin B1 and CDK1/cyclin A. RO-3306 allows for effective cell synchronisation in early mitosis. NÚMERO DE CAS 872573-93-8

Roscovitinesc-24002Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases. Selective for Cdk1, Cdk2, and Cdk5; Roscovitine also inhibits M-phase promoting factor kinase activity, and effects calcium channel gating. NÚMERO DE CAS 186692-46-6

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SU 9516sc-222330SU 9516 is a cell permeable, potent, selective and ATP-competitive inhibitor of CDK2/cyclin A, CDK1/cyclin B, and CDK4/cyclin D1. NÚMERO DE CAS 377090-84-1

Linoleic Acidsc-200788Linoleic Acid is a fatty acid that has been observed to influence the inflammatory process and regulate the functions of neutrophils. NÚMERO DE CAS 60-33-3

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Triciribinesc-200661Triciribine (also: API-2) is known to suppress the phosphorylation level and kinase activity of Akt. Selectively inhibits Akt1, Akt2, and Akt3 without inhibiting known upstream activators, PDK1 and PI 3-Kinase, of Akt. NÚMERO DE CAS 35943-35-2

D-myo-Inositol 1,3,4,5,6-pentakisphosphate pentapotassium saltsc-221502

Naltrindole Hydrochloridesc-202236Naltrindole Hydrochloride is an apoptotic agent and a cell growth inhibitor. It also has been shown to be a highly potent and selective antagonist of δ opioids (DOR). NÚMERO DE CAS 111469-81-9

NSC 632839 hydrochloridesc-204138NSC 632839 hydrochloride is an inhibitor of USP (ubiquitin isopeptidase) activity that displays no effect on the proteolytic activity of the proteasome. NÚMERO DE CAS 157654-67-6

TMSsc-203708TMS is a strong, selective and competitive inhibitor of cytochrome P450 1B1, an overexpressed enzyme in particular tumors (IC50 = 6 nM). 50- and 520-fold selective over P450 1A1 and 1A2 respectively. TMS inhibits cancer cell growth in vitro. NÚMERO DE CAS 24144-92-1

Ubiquitin Isopeptidase Inhibidor II, F6sc-296678Ubiquitin Isopeptidase Inhibitor II, F6 is a cell-permeable cross-conjugated α,β-unsaturated dienone compound that induces caspase activation and apoptosis via the apoptosome-independent mitochondrial pathway. NÚMERO DE CAS 157654-67-6 (HCl salt)

Betamethasone-d5sc-217751Betamethasone-d5 is a deuterated glucocorticoid that induces gene expression and apoptosis. NÚMERO DE CAS 378-44-9 (unlabeled)

Tazarotenesc-220193Tazarotene is an acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. T NÚMERO DE CAS 118292-40-3

Ganglioside GD3 disodium salt (bovino brain)sc-202623Induces mitochondrial permeability transition (MPT) without requiring elevated Ca2+ levels and thus triggers Fas-mediated apoptosis. NÚMERO DE CAS 62010-37-1

Ganglioside GD3, Disialo, Diammonium Salt, Bovine Buttermilksc-221658Ganglioside GD3, Disialo, Diammonium Salt, Bovine Buttermilk has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma.

Polyinosinic Acid • Polycytidylic Acid, Sodium Salt, Double-Strandedsc-204854Polyinosinic Acid • Polycytidylic Acid, Sodium Salt, Double-Stranded is a TLR3 (Toll-like receptor 3) agonist. NÚMERO DE CAS 42424-50-0

3-Deazaneplanocin, HCl saltsc-3518563-Deazaneplanocin, HCl salt is a carbocyclic analog of adenosine that acts as an effective SAHH (S-adenosylhomocysteine hydrolase) inhibitor. NÚMERO DE CAS 102052-95-9

Epothilone B, Syntheticsc-203944Epothilone B, Synthetic is a structural analog of Epothilone A (sc-207628) with similar biological properties.