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home » Signaling Intermediates » eIF Antibody / eIF Antibodies » eIF2Bδ (P-6): sc-9981

eIF2Bδ (P-6) Antibody: sc-9981

  |  Datasheet
  • mouse monoclonal IgG2b; 200 µg/ml
  • raised against full length eIF2Bδ
  • recommended for detection of eIF2Bδ of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
 
Additional eIF Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human EIF2B4 8890 2p23.3 NM_001034116, NM_015636, NM_172195 Q9UI10
 606687
Mouse Eif2b4 13667 5 B1 Q61749
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
eIF2Bδ (P-6) sc-9981 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
eIF2Bδ siRNA (h) sc-35276 10 µM $258
eIF2Bδ siRNA (m) sc-35277 10 µM $258
eIF2Bδ (h)-PR sc-35276-PR 10 µM $23
eIF2Bδ (m)-PR sc-35277-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
eIF2Bδ shRNA Plasmid (h) sc-35276-SH 20 µg $520
eIF2Bδ shRNA Plasmid (m) sc-35277-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
eIF2Bδ shRNA (h) Lentiviral Particles sc-35276-V 200 µl $625
eIF2Bδ shRNA (m) Lentiviral Particles sc-35277-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
KNRK Whole Cell Lysate sc-2214 500 µg/200 µl $104
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
eIF2Bδ (h): 293T Lysate sc-111518 100µg/200µl $205

eIF2Bδ Background Information
The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF2B exists as a five subunit complex composed of eIF2Bå, eIF2Bß, eIF2B©, eIF2B∂, and eIF2Bé. The eIF2B complex catalyzes the exchange of GDP for GTP on the eIF2 complex, following the interaction of eIF2/GTP with the 40S ribosomal subunit. Guanine nucleotide exchange factor (GEF) activity is exhibited by the eIF2Bé subunit alone, but is greater in the presence of all five eIF2B subunits. Phosphorylation of eIF2 inhibits GEF activity of eIF2B, an inhibition that requires the eIF2Bå subunit.

eIF2Bδ (P-6) Product Citations
See how others have used eIF2Bδ (P-6): sc-9981 antibody and or eIF2Bδ (P-6) antibody conjugates.


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eIF2Bδ (P-6)
Click on image to enlarge
sc-9981
eIF2Bδ (P-6): sc-9981. Western blot analysis of eIF2Bδ expression in KNRK (A) and K-562 (B) whole cell lysates.
sc-9981
eIF2Bδ (P-6): sc-9981. Immunofluorescence staining of methanol-fixed KNRK cells showing cytoplasmic staining.
sc-9981
eIF2Bδ (P-6): sc-9981. Western blot analysis of eIF2Bδ expression in non-transfected 293T: sc-117752 (A), human eIF2Bδ transfected 293T: sc-111518 (B) and K-562 (C) whole cell lysates.
sc-9981
eIF2Bδ (P-6): sc-9981. Western blot analysis of eIF2Bδ expression in non-transfected 293T: sc-117752 (A), mouse eIF2Bδ transfected 293T: sc-119970 (B), K-562 (C) and COLO 320DM (D) whole cell lysates.
sc-9981
eIF2Bδ (P-6): sc-9981. Immunoperoxidase staining of formalin fixed, paraffin-embedded human smooth muscle tissue showing cytoplasmic staining of smooth muscle cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
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