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PACSIN3 (H-100) Antibody: sc-99128 |
| Datasheet |
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- rabbit polyclonal IgG, 200µg/ml
- epitope corresponding to amino acids 151-250 mapping within an internal region of PACSIN3 of human origin
- recommended for detection of PACSIN3 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
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Ordering Information
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
PACSIN3 |
29763 |
11p11.2 |
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Q9UKS6
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606513 |
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PACSIN3 Background Information
PACSINs are a family of cytoplasm-resisdent phosphoproteins that aid in vesicle formation and transport. It is presumed that all isoforms oligomerize and bind dynamin, synaptojanin 1 and N-WASP through their Src homology 3 domains. Furthermore, PACSINs colocalize with dynamin, but not with clathrin, indicating that the proteins may play a specific role with a defined population of dynamin at distinct cellular locations. PACSIN3 (Protein Kinase C and Casein Kinase Substrate in Neurons 3) contains a short proline-rich region and lacks asparagine-proline-phenylalanine motifs, which differentiates it from the rest of the PACSIN family. Sequence analysis of cDNAs encoding mouse and human PACSIN3 predict that the human protein consists of 424-amino acids and is 94% identical to the mouse protein. Studies of the mouse protein report predominant expression in mouse lung, skeletal muscle, and heart as well as in brain, kidney, and uterus. |
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PACSIN3 (H-100)
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PACSIN3 (H-100): sc-99128. Western blot analysis of PACSIN3 expression in non-transfected 293T: sc-117752 (A), mouse PACSIN3 transfected 293T: sc-127289 (B) and HeLa (C) whole cell lysates. |
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