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AGA Antibody (H-300): sc-98735

 |  Datasheet

(Based on data analysis)

  • AGA Antibody (H-300) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 47-272 mapping at the C-terminus of AGA of human origin
  • recommended for detection of AGA of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine and porcine
 

See additional AGA Antibodies.

Ordering InformationGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
AGA Antibody (H-300) sc-98735 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AGA siRNA (h) sc-89013 10 µM $258
AGA siRNA (m) sc-105048 10 µM $258
AGA (h)-PR sc-89013-PR 10 µM, 20 µl $23
AGA (m)-PR sc-105048-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AGA shRNA Plasmid (h) sc-89013-SH 20 µg $520
AGA shRNA Plasmid (m) sc-105048-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AGA shRNA (h) Lentiviral Particles sc-89013-V 200 µl $625
AGA shRNA (m) Lentiviral Particles sc-105048-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
AGA (h2): 293T Lysate sc-170753 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human AGA 175 4q34.3 P20933
208400
 


AGA (aspartylglucosaminidase) is a 346 amino acid precursor protein that belongs to the Ntn-hydrolase family and is cleaved to produce an alpha chain and a beta chain. Localized to the lysosome, AGA functions as a heterotetramer composed of two alpha and two beta chains that work together to cleave the GlcNAc-Asn bond that joins oligosaccharides to target glycoproteins. Defects in the gene encoding AGA are the cause of aspartylglucosaminuria (AGU), a lysosomal storage disease that is characterized by severe mental retardation and mild connective tissue abnormalities. The gene encoding AGA maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.

AGA Antibody (H-300) Data
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AGA (H-300): sc-98735. Western blot analysis of AGA expression in non-transfected: sc-117752 (A) and human AGA transfected: sc-112982 (B) 293T whole cell lysates.
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