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SERGEF Antibody (H-128): sc-98650

 |  Datasheet

(Based on data analysis)

  • SERGEF Antibody (H-128) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 17-144 mapping within an internal region of SERGEF of human origin
  • recommended for detection of SERGEF of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine and porcine
 
Full-length SERGEF protein sequence with immunogen highlighted:
MEREPSASEAAPAAAALFAWGANSYGQLGLGHKEDVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCGLNKDGQLGLGHTEDIPYFTPCKSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVCIAAGLRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGATEVSCGSEHNLAIIGGVCYSWGWNEHGMCGDGTEANVWAPKPVQALLSSSGLLVGCGAGHSLALCQLPAHPALVQDPKVTYLSPDAIEDTESQKAMDKERNWKERQSETSTQSQSDWSRNGGL

See additional SERGEF Antibodies.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
SERGEF Antibody (H-128) sc-98650 200 µg/ml $279
 CRISPR/Cas9 KO and HDR Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
SERGEF CRISPR/Cas9 KO Plasmid (h) sc-411911 20 µg $345
SERGEF HDR Plasmid (h) sc-411911-HDR 20 µg $385
SERGEF CRISPR/Cas9 KO Plasmid (m) sc-424280 20 µg $345
SERGEF HDR Plasmid (m) sc-424280-HDR 20 µg $385
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
SERGEF siRNA (h) sc-96513 10 µM $258
SERGEF siRNA (m) sc-153345 10 µM $258
SERGEF (h)-PR sc-96513-PR 10 µM, 20 µl $23
SERGEF (m)-PR sc-153345-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
SERGEF shRNA Plasmid (h) sc-96513-SH 20 µg $520
SERGEF shRNA Plasmid (m) sc-153345-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
SERGEF shRNA (h) Lentiviral Particles sc-96513-V 200 µl $625
SERGEF shRNA (m) Lentiviral Particles sc-153345-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SERGEF 26297 11p15.1 Q9UGK8
606051
 


SERGEF (secretion-regulating guanine nucleotide exchange factor), also called DelGEF (deafness locus-associated putative guanine nucleotide exchange factor), is a guanine nucleotide exchange factor which is thought to be involved in secretion pathways. SERGEF associates with Sec5, a protein required for secretion, in a magnesium-dependent manner and is stimulated by the presence of deoxycytidine triphosphate (dCTP) or guanosine triphosphate (GTP). A homolog of RanGEF, SERGEF is localized to the nucleus and cytoplasm and is expressed throughout the body with high expression observed in the brain, placenta and skeletal muscle. SERGEF is a 458 amino acid protein which, upon DNA damage, is phosphorylated by Atm or ATR. Two isoforms exist due to alternative splicing.

SERGEF Antibody (H-128) Data
Click on image to enlarge
SERGEF (H-128): sc-98650. Western blot analysis of SERGEF expression in HeLa whole cell lysate.
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